Propyphenazone

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Ophthalmic Ketorolac Injection Ketorolac Nasal Spray Ketorolac Pemetrexed Injection Cyclosporine Ophthalmic
4 Contraindicated 59 Major 28 Moderate
All (91) Contraindicated (4) Major (59) Moderate (28)

Moderate

Propyphenazone Lisinopril Prinivil Explained Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Atenolol Tenormin Explained Reduced antihypertensive effect Details Propyphenazone Acebutolol Sectral® Reduced antihypertensive effect Details Propyphenazone Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Betaxolol Betoptic S Reduced antihypertensive effect Details Propyphenazone Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Propyphenazone Bisoprolol Zebeta® Reduced antihypertensive effect Details Propyphenazone Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Propyphenazone Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Esmolol Brevibloc Reduced antihypertensive effect Details Propyphenazone Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Labetalol Normodyne® Reduced antihypertensive effect Details Propyphenazone Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect Details Propyphenazone Levofloxacin Levaquin An increased risk of seizures Details Propyphenazone Levofloxacin Injection Levaquin An increased risk of seizures Details Propyphenazone Losartan Arbli Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Moexipril Univasc® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Propyphenazone Nadolol Corgard Reduced antihypertensive effect Details Propyphenazone Nebivolol Bystolic Reduced antihypertensive effect Details Propyphenazone Ofloxacin Floxin® An increased risk of seizures Details Propyphenazone Ofloxacin Ophthalmic Ocuflox An increased risk of seizures Details Propyphenazone Ofloxacin Otic Floxin® Otic An increased risk of seizures Details Propyphenazone Penbutolol Levatol® Reduced antihypertensive effect Details Propyphenazone Perindopril Aceon Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.