Quinapril

62 interactions 1 explained in plain English
Also sold as: Accupril Accupril®
About Quinapril

Quinapril is an ACE inhibitor used to treat high blood pressure and heart failure. Read the full Quinapril drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Quinapril Aspirin Acuprin® Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Quinapril Aspirin Rectal Aspirin Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Quinapril Azathioprine Azasan Myelosuppression Details Quinapril Azilsartan Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Quinapril Cyclosporine Injection Atopica Acute renal dysfunction and an increased risk of hyperkalemia Details Quinapril Cyclosporine Ophthalmic Cequa Acute renal dysfunction and an increased risk of hyperkalemia Details Quinapril Digoxin Cardoxin® An increased digoxin exposure Details Quinapril Eprosartan Teveten® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Quinapril Everolimus Afinitor Increased risk of angioedema Details Quinapril Furosemide Injection Disal An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Quinapril Irbesartan Avapro Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Quinapril Lithium Carbonate Lithobid Increased risk of lithium toxicity Details Quinapril Losartan Arbli Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Quinapril Melphalan Alkeran An increased risk of severe hypotension Details Quinapril Melphalan Injection Alkeran An increased risk of severe hypotension Details Quinapril Mercaptopurine Purinethol® Myelosuppression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.