Sulfinpyrazone

Name: Sulfinpyrazone Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

69 interactions 5 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abrocitinib Defibrotide Injection Sertraline Fondaparinux Melphalan Injection Enoxaparin Injection

2 Contraindicated 49 Major 16 Moderate 2 Minor

All (69) Contraindicated (2) Major (49) Moderate (16) Minor (2)

Major

Sulfinpyrazone Mefenamic Acid Ponstel® An increased risk of bleeding Details Sulfinpyrazone Meloxicam Alloxate An increased risk of bleeding Details Sulfinpyrazone Meloxicam Injection Alloxate An increased risk of bleeding Details Sulfinpyrazone Melphalan Alkeran An increased risk of bleeding Details Sulfinpyrazone Melphalan Injection Alkeran An increased risk of bleeding Details Sulfinpyrazone Nabumetone Relafen An increased risk of bleeding Details Sulfinpyrazone Naproxen Aleve An increased risk of bleeding Details Sulfinpyrazone Nifedipine Adalat® Reduced NIFEdipine exposure Details Sulfinpyrazone Pegloticase Injection Krystexxa Increased risk of anaphylaxis and infusion reactions Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.