Tafamidis

Name: Tafamidis Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

4 interactions

Also sold as: Vyndamax Vyndamax® Vyndaqel Vyndaqel® (tafamadis meglumine)

About Tafamidis

Tafamidis is used to treat transthyretin amyloid cardiomyopathy (ATTR-CM; a condition in which a protein (transthyretin) builds up in the wall of the heart making it thicker which makes it difficult for the heart to pump blood adequately). Tafamidis is in a class of medications called transthyretin stabilizers. It work… Read the full Tafamidis drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Irinotecan Irinotecan Injection Methotrexate Methotrexate Injection

4 Major

All (4) Major (4)

Major

Tafamidis Irinotecan Camptosar Increased BCRP substrate exposure and an increased risk of the substrate-related toxicities Details Tafamidis Irinotecan Injection Camptosar Increased BCRP substrate exposure and an increased risk of the substrate-related toxicities Details Tafamidis Methotrexate Jylamvo Increased BCRP substrate exposure and an increased risk of the substrate-related toxicities Details Tafamidis Methotrexate Injection Abitrexate® Increased BCRP substrate exposure and an increased risk of the substrate-related toxicities Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.