Tenofovir Disoproxil Fumarate

Name: Tenofovir Disoproxil Fumarate Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

31 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aspirin Etodolac Bromfenac Ophthalmic Diclofenac Ophthalmic Mefenamic Acid Ibuprofen

25 Major 6 Moderate

All (31) Major (25) Moderate (6)

Moderate

Tenofovir Disoproxil Fumarate Cyclosporine Injection Atopica Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details Tenofovir Disoproxil Fumarate Cyclosporine Ophthalmic Cequa Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details Tenofovir Disoproxil Fumarate Elacestrant Orserdu Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details Tenofovir Disoproxil Fumarate Fostamatinib Tavalisse Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details Tenofovir Disoproxil Fumarate Lenacapavir Injection Sunlenca Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details Tenofovir Disoproxil Fumarate Lenacapavir Oral Sunlenca Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.