Toloxatone

Name: Toloxatone Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

4 interactions 2 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Amitriptyline Sertraline Diethylpropion Levodopa Oral Inhalation

4 Contraindicated

All (4) Contraindicated (4)

Contraindicated

Toloxatone Amitriptyline Elavil Explained Neurotoxicity, seizures, or serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Toloxatone Sertraline Explained CNS toxicity or serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Toloxatone Diethylpropion Tenuate Hypertensive crisis (headache, hyperpyrexia, hypertension) Details Toloxatone Levodopa Oral Inhalation Inbrija Hypertension Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.