Voclosporin

Name: Voclosporin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

92 interactions 7 explained in plain English

Also sold as: Lupkynis Lupkynis®

About Voclosporin

Voclosporin is used in combination with other mycophenolate mofetil (Cellcept) and corticosteroids like methylprednisolone or prednisone for treatment of lupus nephritis (an autoimmune disease in which the immune system attacks the kidneys) in adults. Voclosporin is in a class of medications called immunosupressants. I… Read the full Voclosporin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Lefamulin Ketoconazole Topical Oxaliplatin Injection Hydroxychloroquine Atogepant Ivabradine

2 Contraindicated 89 Major 1 Moderate

All (92) Contraindicated (2) Major (89) Moderate (1)

Contraindicated

Voclosporin Ketoconazole Topical Extina® Foam Increased voclosporin exposure and an increased risk of QT interval prolongation Details Voclosporin Lefamulin Xenleta Increased lefamulin exposure, an increased risk of lefamulin-related adverse reactions, increased voclosporin exposure, an increas... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.