Drug & supplement interaction

Abscess Root + Roflumilast

Roflumilast brand names: Daliresp, Zoryve.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Abscess Root and Roflumilast in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Abscess Root and Roflumilast

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Roflumilast and Abscess Root in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Abscess Root at all — not against Roflumilast, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Abscess Root safety at a glance

Abscess Root overall Use caution There is little modern safety data, so use cautiously and only under guidance.
Pregnancy Avoid Not enough safety information exists, so avoid during pregnancy.
Breastfeeding Avoid Safety is unknown, so it is best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Roflumilast and Abscess Root? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Roflumilast’s Own FDA Label Lists

This is not an interaction — none of it involves Abscess Root. These are the most notable effects listed in the ADVERSE REACTIONS section of Roflumilast’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Hives Worth acting on
  • A higher chance of infection Worth acting on
  • A stuffy or runny nose
  • Trouble sleeping
  • Diarrhea
  • A skin rash
  • Vomiting
  • Headache
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Roflumilast. Read the label on DailyMed › Abscess Root’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Abscess Root side to compare — that is a limit of the record, not a statement that Abscess Root has no side effects.

Everything else you take

See Every Supplement That Interacts With Roflumilast

This page covers Abscess Root only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Roflumilast page lists 141 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 96 moderate · 42 minor.

From our pharmacist’s overview on the Roflumilast page

“Roflumilast (Daliresp for severe COPD, Zoryve as a cream for skin conditions) is cleared almost entirely by one liver enzyme, CYP3A4, which is why 121 of the 141 supplements on this page can push its level up or down, and why real caution is warranted here. Start with the three rated major: grapefruit blocks that enzyme and can raise r…”

Reviewed by 2 · Jul 18, 2026

Open the Roflumilast interaction page

How much people look this up

Where Abscess Root and Roflumilast Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Abscess Root
Steady interest

#727 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Roflumilast
Top half

#1,225 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Abscess Root is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Abscess Root reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Abscess Root and Roflumilast records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Abscess Root

What is Abscess Root?

Abscess Root
  • Coughs and bronchitis
  • Fever and promoting sweating
  • Skin sores and inflammation
  • Astringent for mucous membranes

Abscess Root (Polemonium reptans) is a North American herb used in traditional medicine for coughs, fevers, and skin problems, but there is very little modern scientific research to support these uses. Because its safety has not been well studied, it is best to use it cautiously and to talk with a pharmacist or doctor before trying it.

Polemonium reptans · Polemoniaceae · Root and rhizome · Tea (decoction), tincture, dried root, occasionally capsules

An interaction check asks whether these two react with each other — it does not ask whether Abscess Root is a good idea for someone in your situation. Here is what our Abscess Root record says about it on its own.

Abscess Root: dosing

There is no established or standardized dose for Abscess Root. Traditional use involved teas or tinctures made from the dried root, but reliable, modern dosing guidance does not exist.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Abscess Root monograph — the full record covers uses, side effects and every documented interaction.

Read the full Abscess Root monograph & all interactions
Medication

About Roflumilast

What Is Roflumilast Used For?

Brand names: Daliresp, Zoryve

Daliresp and roflumilast tablets are used to reduce the risk of COPD (chronic obstructive pulmonary disease) flare-ups in adults with severe COPD linked to chronic bronchitis who have had flare-ups in the past. They are not rescue inhalers and will not relieve a sudden breathing attack.

Zoryve cream is used topically to treat plaque psoriasis (adults and children 2+) and mild to moderate atopic dermatitis (eczema) in adults and children as young as 2. Zoryve topical foam is used to treat seborrheic dermatitis (adults and children 9+) and plaque psoriasis of the scalp and body (adults and children 12+).

Most-Reported Side Effects for Roflumilast

From FAERS, the FDA’s public side-effect reporting system (6,927 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 1,054 reports
Chronic obstructive pulmonary disease 657 reports
Diarrhea 596 reports
Nausea 491 reports
Pneumonia 476 reports
See full Roflumilast drug information
Keep checking

Other Drugs & Abscess Root

Browse every other medication we’ve checked against Abscess Root — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Abscess Root against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Abscess Root list.

See the full Abscess Root interactions page
See every supplement checked against Roflumilast, ranked by severity
Evidence & sources

Abscess Root References

The 2 sources that drive our Abscess Root monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Abscess Root is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Abscess Root and Roflumilast Together: Common Questions

Is it safe to take Abscess Root with Roflumilast?
We do not list a known interaction between Abscess Root and Roflumilast. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Roflumilast interact with any supplements?
Yes. Roflumilast has documented interactions with 141 supplements in our database — Abscess Root is not one of them. The Roflumilast interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Abscess Root monograph Uses, safety profile, and every drug interaction in one place Roflumilast drug information The full plain-English guide to this medication Roflumilast supplement interactions Every supplement checked against Roflumilast, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Roflumilast and Abscess Root?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.