Drug & supplement interaction

Acupuncture + Tenapanor Hydrochloride

Tenapanor Hydrochloride brand name: Ibsrela.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Acupuncture and Tenapanor Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Acupuncture and Tenapanor Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tenapanor Hydrochloride and Acupuncture in our sources. This does not guarantee that the combination is completely free of risk — research on Acupuncture alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Acupuncture at all — not against Tenapanor Hydrochloride, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Acupuncture is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Acupuncture safety at a glance

Acupuncture overall Use caution Generally safe when performed by a licensed practitioner with sterile, single-use needles.

Pregnancy Possibly Safe When used appropriately at most acupoints and performed with sterile needles. Some clinical research shows that acupuncture has been used during pregnancy and l... Read the full pregnancy detail

Breastfeeding Possibly Safe When used appropriately at most acupoints and performed with sterile needles. Some clinical research shows that acupuncture has been used during pregnancy and l... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tenapanor Hydrochloride and Acupuncture? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

No Interaction Found — But Data Suggests Acupuncture and Tenapanor Hydrochloride May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so having Acupuncture while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do.

Dizziness Additional detail
Acupuncture
“Fainting and dizziness have been reported rarely. Tiredness, transient sedation, and vasovagal shock have also been reported rarely. Numbness has been reported rarely. Crying and irritability have been reported.”

Acupuncture · Natural Medicines adverse-effect record, reported in vertigo.
6 sources cited

102639. Fan W, Kuang X, Hu J, et al. Acupuncture therapy for poststroke spastic hemiplegia: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Clin Pract. 2020;40:101176. PubMed

102646. Zhang L, Tang Y, Hui R, et al. The effects of active acupuncture and placebo acupuncture on insomnia patients: a randomized controlled trial. Psychol Health Med. 2020:1-15. PubMed

103432. Qin X, Coyle ME, Yang L, et al. Acupuncture for recurrent urinary tract infection in women: a systematic review and meta-analysis. BJOG. 2020.

103435. Fan SQ, Jin S, Tang TC, Chen M, Zheng H. Efficacy of acupuncture for migraine prophylaxis: a trial sequential meta-analysis. J Neurol. 2020. PubMed

105403. Jang A, Brown C, Lamoury G, et al. The effects of acupuncture on cancer-related fatigue: updated systematic review and meta-analysis. Integr Cancer Ther. 2020;19:1534735420949679. PubMed

104723. Yang XY, Yang NB, Huang FF, Ren S, Li ZJ. Effectiveness of acupuncture on anxiety disorder: a systematic review and meta-analysis of randomised controlled trials. Ann Gen Psychiatry. 2021;20(1):9. PubMed
Tenapanor Hydrochloride

Listed in the ADVERSE REACTIONS section of the FDA label for Tenapanor Hydrochloride. Read the label on DailyMed ›

Reported for Acupuncture but not commonly for Tenapanor Hydrochloride: stomach upset, back pain, constipation and mood changes or irritability.

Effects for Tenapanor Hydrochloride come from the ADVERSE REACTIONS section of its FDA label; effects for Acupuncture come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 1,216 voluntary FDA FAERS reports for Tenapanor Hydrochloride that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Acupuncture in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Safe

When used appropriately at most acupoints and performed with sterile needles. Some clinical research shows that acupuncture has been used during pregnancy and labor without reports of significant adverse effects. POSSIBLY UNSAFE...when acupuncture at the SP6 acupoint is used. There is some concern that this acupoint can increase the risk of early contractions and miscarriage. Most evidence also suggests that acupuncture is safe for patients undergoing in vitro fertilization (IVF). One large clinical study and a meta-analysis show that receiving acupuncture one or more times between follicle stimulation and pregnancy testing does not affect the pregnancy or live birth rate when compared with sham acupuncture or no intervention. However, a smaller study shows that acupuncture performed off-site immediately before and after IVF embryo transfer reduces the pregnancy rate by 21% when compared to no additional intervention. Use caution until more is known about the safety of acupuncture during IVF. There is insufficient reliable information available about the use of electroacupuncture or laser acupuncture during pregnancy; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Tenapanor Hydrochloride

This page covers Acupuncture only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tenapanor Hydrochloride page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Tenapanor Hydrochloride page

“Tenapanor hydrochloride (Ibsrela) works in the gut to relieve irritable bowel syndrome with constipation, and its supplement interaction list deserves genuine care rather than a quick skim. Three of the 138 ingredients on file rate major: grapefruit, St.”

Reviewed by 2 · Jul 18, 2026

Open the Tenapanor Hydrochloride interaction page

How much people look this up

Where Acupuncture and Tenapanor Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Acupuncture

Steady interest

#743 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Tenapanor Hydrochloride

Top 5%

#83 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Acupuncture reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Acupuncture and Tenapanor Hydrochloride records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Treatment approach

About Acupuncture

What is Acupuncture?

Chronic pain
Low back and neck pain
Osteoarthritis (especially knee)
Headache and migraine
Nausea and vomiting
Stress and well-being

Acupuncture is a traditional Chinese medicine practice that involves inserting thin needles into specific points on the body. There is moderate evidence it may help certain types of chronic pain and nausea, while evidence for many other uses is weak or unclear. When done by a licensed, trained practitioner using sterile, single-use needles, it is generally considered safe for most people.

Not applicable (a physical therapy, not an herb or supplement) · Manual needling, electroacupuncture, ear (auricular) acupuncture, acupressure, laser acupuncture

An interaction check asks whether these two react with each other — it does not ask whether Acupuncture is a good idea for someone in your situation. Here is what our Acupuncture record says about it on its own.

Acupuncture: dosing

There is no standard "dose" for acupuncture the way there is for a pill. Treatment plans differ by practitioner and condition. If you are not seeing benefit after a reasonable trial, discuss whether to continue.

From our Acupuncture monograph — the full record covers uses, side effects and every documented interaction.

Read the full Acupuncture monograph & all interactions

Medication

About Tenapanor

What Is Tenapanor Used For?

Brand name: Ibsrela

Tenapanor is approved for two distinct conditions, each under a separate brand. Ibsrela is used to treat irritable bowel syndrome with constipation (IBS-C) in adults. XPHOZAH is used to reduce high phosphorus levels (hyperphosphatemia) in adults with chronic kidney disease (CKD) who are on dialysis — specifically as an add-on when phosphate binders haven't worked well enough or aren't tolerated.

Most-Reported Side Effects for Tenapanor Hydrochloride

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 1,239 reports

Therapy interrupted 292 reports

Abdominal distension 234 reports

Insurance issue 184 reports

Intentional underdose 167 reports

See full Tenapanor drug information

Keep checking

Other Drugs & Acupuncture

Browse every other medication we’ve checked against Acupuncture — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Acupuncture against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Acupuncture list.

See the full Acupuncture interactions page

See every supplement checked against Tenapanor Hydrochloride, ranked by severity

Evidence & sources

Acupuncture References

The 99 references that drive our Acupuncture monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Smith CA, Collins CT, Cyna AM, Crowther CA. Complementary and alternative therapies for pain management in labour. Cochrane Database Syst Rev 2006;(4):CD003521. PubMed
Smith, C., Crowther, C., and Beilby, J. Acupuncture to treat nausea and vomiting in early pregnancy: a randomized controlled trial. Birth 2002;29(1):1-9. PubMed
Helmreich, R. J., Shiao, S. Y., and Dune, L. S. Meta-analysis of acustimulation effects on nausea and vomiting in pregnant women. Explore (NY) 2006;2(5):412-421. PubMed
Carlsson, C. P., Axemo, P., Bodin, A., Carstensen, H., Ehrenroth, B., Madegard-Lind, I., and Navander, C. Manual acupuncture reduces hyperemesis gravidarum: a placebo- controlled, randomized, single-blind, crossover study. J Pain Symptom Manage 2000;20(4) PubMed
Habek, D., Barbir, A., Habek, J. C., Janculiak, D., and Bobic-Vukovic, M. Success of acupuncture and acupressure of the Pc 6 acupoint in the treatment of hyperemesis gravidarum. Forsch Komplementarmed Klass Naturheilkd 2004;11(1):20-23. PubMed
Guerreiro da Silva, J. B., Nakamura, M. U., Cordeiro, J. A., and Kulay, L., Jr. Acupuncture for low back pain in pregnancy--a prospective, quasi-randomised, controlled study. Acupunct Med 2004;22(2):60-67. PubMed
Hantoushzadeh, S., Alhusseini, N., and Lebaschi, A. H. The effects of acupuncture during labour on nulliparous women: a randomised controlled trial. Aust N Z J Obstet Gynaecol 2007;47(1):26-30. PubMed
Selmer-Olsen, T., Lydersen, S., and Morkved, S. Does acupuncture used in nulliparous women reduce time from prelabour rupture of membranes at term to active phase of labour? A randomised controlled trial. Acta Obstet Gynecol Scand 2007;86(12):1447-1452. PubMed
Craig LB, Rubin LE, Peck JD, Anderson M, Marshall LA, Soules MR. Acupuncture performed before and after embryo transfer: a randomized controlled trial. J Reprod Med. 2014;59(5-6):313-20.
Smith CA, de Lacey S, Chapman M, et al. Effect of Acupuncture vs Sham Acupuncture on Live Births Among Women Undergoing In Vitro Fertilization: A Randomized Clinical Trial. JAMA. 2018;319(19):1990-1998. PubMed
Choi ME, Jung CJ, Won CH, et al. Case report of cutaneous nodule caused by Gordonia bronchialis in an immunocompetent patient after receiving acupuncture. J Dermatol. 2019;46(4):343-346.
Domenicucci M, Marruzzo D, Pesce A, Raco A, Missori P. Acute Spinal Epidural Hematoma After Acupuncture: Personal Case and Literature Review. World Neurosurg. 2017;102:695.e11-695.e14. PubMed
Eghbal K, Ghaffarpasand F. An Acute Cervical Subdural Hematoma as the Complication of Acupuncture: Case Report and Literature Review. World Neurosurg. 2016 Nov;95:616.e11-616.e13. PubMed
Glas AW, Jüttner AM, Kooter AJ. Necrotising fasciitis after acupuncture treatment in an immunocompetent patient. BMJ Case Rep. 2016;2016. pii: bcr2016216405. PubMed
Jian J, Shao Y, Wan L, et al. Autopsy diagnosis of acupuncture-induced bilateral tension pneumothorax using whole-body postmortem computed tomography: A case report. Medicine (Baltimore). 2018;97(44):e13059. PubMed
Kim D, Lee S. An autopsy case of fatal acute peritonitis complicated by illegal acupuncture therapy. Forensic Sci Int. 2017;276:e13-e15. PubMed
Narasimhalu K, Ting SKS, Lim SH. Post-acupuncture headache: an unfortunate case of an inadvertent lumbar puncture. Singapore Med J. 2018;59(10):557-558. PubMed
Oskarsson P, Walker CA, Leigh-Smith S. Bilateral pneumothoraces following acupuncture. BMJ Case Rep. 2017. pii: bcr-2017-221310. PubMed
Sanchez DR, Bradfield JS, Traina MI, Wachsner RY. Acupuncture Needle in the Heart. Tex Heart Inst J. 2017;44(6):426-428. PubMed
Shuang H, Yichun K. A case of perforating injury of eyeball and traumatic cataract caused by acupuncture. Indian J Ophthalmol. 2016;64(4):326-7. PubMed
Wigger O, Stortecky S, Most H, Englberger L. Cardiac perforation as a rare complication of acupuncture. Eur Heart J. 2016;37(17):1383. PubMed
Hou W, Pei L, Song Y, et al. Acupuncture therapy for breast cancer-related lymphedema: A systematic review and meta-analysis. J Obstet Gynaecol Res. 2019;45(12):2307-2317. PubMed
Yu S, Zhu L, Xie P, et al. Effects of acupuncture on breast cancer-related lymphoedema: A systematic review and meta-analysis. Explore (NY). 2020;16(2):97-102. PubMed
He Y, Guo X, May BH, et al. Clinical evidence for association of acupuncture and acupressure with improved cancer pain: A systematic review and meta-analysis. JAMA Oncol. 2019;6(2):271-8. PubMed
Hwang MS, Lee HY, Choi TY, et al. A systematic review and meta-analysis of the efficacy of acupuncture and electroacupuncture against chemotherapy-induced peripheral neuropathy. Medicine (Baltimore). 2020;99(17):e19837. PubMed
Wang L, Xu J, Zhan Y, Pei J. Acupuncture for obstructive sleep apnea (OSA) in adults: A systematic review and meta-analysis. Biomed Res Int. 2020;2020:6972327. PubMed
Fan W, Kuang X, Hu J, et al. Acupuncture therapy for poststroke spastic hemiplegia: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Clin Pract. 2020;40:101176. PubMed
Zhang J, Liu Y, Huang X, et al. Efficacy comparison of different acupuncture treatments for functional dyspepsia: A systematic review with network meta-analysis. Evid Based Complement Alternat Med. 2020;2020:3872919. PubMed
Huang Z, Liu S, Zhou J, Yao Q, Liu Z. Efficacy and safety of acupuncture for chronic discogenic sciatica, a randomized controlled sham acupuncture trial. Pain Med. 2019;20(11):2303-2310. PubMed
Garland SN, Xie SX, DuHamel K, et al. Acupuncture versus cognitive behavioral therapy for insomnia in cancer survivors: A randomized clinical trial. J Natl Cancer Inst. 2019;111(12):1323-1331. PubMed
Garcia MK, Meng Z, Rosenthal DI, et al. Effect of true and sham acupuncture on radiation-induced xerostomia among patients with head and neck cancer: A randomized clinical trial. JAMA Netw Open. 2019;2(12):e1916910. PubMed
Zhang L, Tang Y, Hui R, et al. The effects of active acupuncture and placebo acupuncture on insomnia patients: a randomized controlled trial. Psychol Health Med. 2020:1-15. PubMed
Mak TC, Chen HY, Cho WC. Acupuncture for overactive bladder in adults: a systematic review and meta-analysis. Acupunct Med. 2019;37(6):321-331. PubMed
Foroughinia S, Hessami K, Asadi N, et al. Effect of acupuncture on pregnancy-related insomnia and melatonin: A single-blinded, randomized, placebo-controlled trial. Nat Sci Sleep. 2020;12:271-278.
Pei L, Geng H, Guo J, et al. Effect of acupuncture in patients with irritable bowel syndrome: A randomized controlled trial. Mayo Clin Proc. 2020;95(8):1671-1683. PubMed
Qin X, Coyle ME, Yang L, et al. Acupuncture for recurrent urinary tract infection in women: a systematic review and meta-analysis. BJOG. 2020.
Huang K, Liang S, Chen L, Grellet A. Acupuncture for tinnitus: a systematic review and meta-analysis of randomized controlled trials. Acupunct Med. 2020:964528420938380. PubMed
Fan SQ, Jin S, Tang TC, Chen M, Zheng H. Efficacy of acupuncture for migraine prophylaxis: a trial sequential meta-analysis. J Neurol. 2020. PubMed
Zhong L, Wang J, Li F, Bao X, Liu H, Wang P. The effectiveness of acupuncture for dysphagia after stroke: A systematic review and meta-analysis. Evid Based Complement Alternat Med. 2021;2021:8837625. DOI
Yang XY, Yang NB, Huang FF, Ren S, Li ZJ. Effectiveness of acupuncture on anxiety disorder: a systematic review and meta-analysis of randomised controlled trials. Ann Gen Psychiatry. 2021;20(1):9. PubMed
Tu JF, Yang JW, Shi GX, et al. Efficacy of intensive acupuncture versus sham acupuncture in knee osteoarthritis: A randomized controlled trial. Arthritis Rheumatol. 2021;73(3):448-458. PubMed
Lee B, Lee J, Cheon JH, Sung HK, Cho SH, Chang GT. The efficacy and safety of acupuncture for the treatment of children with autism spectrum disorder: A systematic review and meta-analysis. Evid Based Complement Alternat Med. 2018;2018:1057539. PubMed
Zhang Q, Gong J, Dong H, Xu S, Wang W, Huang G. Acupuncture for chronic fatigue syndrome: a systematic review and meta-analysis. Acupunct Med. 2019;37(4):211-222. PubMed
Jang A, Brown C, Lamoury G, et al. The effects of acupuncture on cancer-related fatigue: updated systematic review and meta-analysis. Integr Cancer Ther. 2020;19:1534735420949679. PubMed
Weagle K, Henneberry RJ, Atkinson P. Pneumothorax Following Acupuncture. Cureus 2021;13(3):e14207. PubMed
Bäumler P, Zhang W, Stübinger T, Irnich D. Acupuncture-related adverse events: systematic review and meta-analyses of prospective clinical studies. BMJ Open 2021;11(9):e045961. PubMed
Yamaguchi R, Makino Y, Torimitsu S, Chiba F, Kihara Y, Iwase H. Fatal bilateral pneumothoraces after electroacupuncture treatment: A case report and literature review. J Forensic Sci 2021. PubMed
Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Comparative Study of the Effect of Licorice Muco-adhesive Film on Radiotherapy Induced Oral Mucositis, A Randomized Controlled Clinical Trial. Gulf J Oncolog 2021;1(37):42-47.
He M, Qin W, Qin Z, Zhao C. Acupuncture for allergic rhinitis: a systematic review and meta-analysis. Eur J Med Res 2022;27(1):58. PubMed
Hullender Rubin LE, Smith CA, Schnyer RN, Tahir P, Pasch LA. Effect of acupuncture on IVF-related anxiety: a systematic review and meta-analysis. Reprod Biomed Online 2022;45(1):69-80. PubMed
Zhang J, Zhang Z, Huang S, et al. Acupuncture for cancer-related insomnia: A systematic review and meta-analysis. Phytomedicine 2022;102:154160. PubMed
Wan OYK, Cheung RYK, Law MPM, Lee LL, Wang RCC, Chan SSC. Effect of additional acupuncture to pelvic floor exercise on urinary incontinence: A randomized controlled trial. Neurourol Urodyn 2022;41(5):1097-1108.
Fan JQ, Lu WJ, Tan WQ, et al. Effectiveness of Acupuncture for Anxiety Among Patients With Parkinson Disease: A Randomized Clinical Trial. JAMA Netw Open 2022;5(9):e2232133. PubMed
Lee B, Ko MM, Lee SH, Chang GT. Acupuncture for the treatment of childhood anorexia: A systematic review and meta-analysis. Complement Ther Med 2022;71:102893. PubMed
Han KH, Cho KH, Han C, et al. The effectiveness and safety of acupuncture treatment on sciatica: A systematic review and meta-analysis. Complement Ther Med 2022;71:102872. PubMed
Rotter G, Ahnert MW, Geue AV, et al. Acupuncture and osteopathic medicine for atopic dermatitis: a three-armed, randomized controlled explorative clinical trial. Clin Exp Dermatol 2022;47(12):2166-2175. PubMed
Hargreaves E, Baker K, Barry G, et al. Acupuncture for treating overactive bladder in adults. Cochrane Database Syst Rev 2022;9(9):CD013519. DOI
Zhu C, Xia W, Huang J, et al. Effects of acupuncture on the pregnancy outcomes of frozen-thawed embryo transfer: A systematic review and meta-analysis. Front Public Health 2022;10:987276. PubMed
Stringer J, Ryder WD, Mackereth PA, Misra V, Wardley AM. A randomised, pragmatic clinical trial of ACUpuncture plus standard care versus standard care alone FOr Chemotherapy Induced peripheral Neuropathy (ACUFOCIN). Eur J Oncol Nurs 2022;60:102171. PubMed
Lee SS. Acupuncture-induced hemopneumothorax: a case report. Acupunct Med 2022;40(6):559-560. PubMed
Qi LY, Yang JW, Yan SY, et al. Acupuncture for the treatment of diarrhea-predominant irritable bowel syndrome: A pilot randomized clinical trial. JAMA Netw Open. 2022;5(12):e2248817. PubMed
Pan J, Jin S, Xie Q, et al. Acupuncture for chronic prostatitis or chronic pelvic pain syndrome: An updated systematic review and meta-analysis. Pain Res Manag 2023;2023:7754876. PubMed
Lun T, Lin S, Chen Y, et al. Acupuncture for children with autism spectrum disorder: A systematic review and meta-analysis. Medicine (Baltimore) 2023;102(8):e33079. PubMed
Jianyu Y, Haiyan LI, Dingyi X, Mingren C, Rixin C. Efficacy of acupuncture therapy for post-stroke fatigue: a systematic review and Meta-analysis. J Tradit Chin Med 2023;43(1):27-33.
Chen M, Xu Y, Fu X, Xie J, Cao X, Xu Y. Wrist-ankle acupuncture for the treatment of acute orthopedic pain after surgery: a meta-analysis. J Orthop Surg Res 2023;18(1):106. PubMed
Lyu J, Wang S, Zhang H, Liu S. Acupuncture-exacerbated pyoderma gangrenosum associated with IgG multiple myeloma. Wounds 2022;34(11):E108-E111. PubMed
Sun W, Zhao Y, Liao L, et al. Effects of acupuncture on age-related macular degeneration: A systematic review and meta-analysis of randomized controlled trials. PLoS One 2023;18(3):e0283375. PubMed
Kwak SG, Kwon JB, Seo YW, Choi WK. The effectiveness of acupuncture as an adjunctive therapy to oral pharmacological medication in patient with knee osteoarthritis: A systematic review and meta-analysis. Medicine (Baltimore) 2023;102(11):e33262. PubMed
Cheng TY, Chiu AW, Chen M. Kidney laceration after acupuncture and Tuina: A case report. Asian J Surg 2023;46(4):1667-1668. PubMed
Xu L, Tan X, Chen X, Du S, Yue X, Qiao D. Rare, fatal pulmonary fat embolism after acupuncture therapy: A case report and literature review. Forensic Sci Int 2023;345:111619. PubMed
Wang Z, Wang Y, Wang C, et al. Systematic review and network meta-analysis of acupuncture combined with massage in treating knee osteoarthritis. Biomed Res Int. 2022;2022:4048550. PubMed
Wu XK, Gao JS, Ma HL, et al. Acupuncture and doxylamine-pyridoxine for nausea and vomiting in pregnancy : A randomized, controlled, 2?×?2 factorial trial. Ann Intern Med 2023;176(7):922-933. PubMed
Wang J, Wu B, Li Y, Wang X, Lu Z, Wang W. Acupuncture in the treatment of post-stroke hiccup: A systematic Review and meta-analysis. Libyan J Med 2023;18(1):2251640. PubMed
Zhan J, Luo Y, Mao W, et al. Efficacy of acupuncture versus rehabilitation therapy on post-stroke shoulder pain: A systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore) 2023;102(29):e34266. PubMed
Chiu WS, Lu YW, Lien TH. Iatrogenic pneumothorax during acupuncture: Case report. Medicina (Kaunas) 2023;59(6):1100. PubMed
Li N, Li O, Sha Z, et al. Efficacy and safety of acupuncture combined with yishen granule in elderly adults with mild cognitive impairment: A multicenter, randomized controlled trial. Altern Ther Health Med 2023;29(6):340-349.
Yan S, Xu M, Zou X, et al. Acupuncture combined with ondansetron for prevention of postoperative nausea and vomiting in high-risk patients undergoing laparoscopic gynaecological surgery: A randomised controlled trial. United European Gastroenterol J 2023; PubMed
Lagerstedt K, Efverman A. A randomized sham-controlled mixed methods pilot study of the feasibility of acupuncture for chemotherapy-induced neuropathy: Lessons learned from patient experiences in integrative cancer care. Integr Cancer Ther 2023;22:1534735 PubMed
Pang J, Shergis JL, Zheng L, et al. Clinical evidence for acupuncture for adult asthma: Systematic review and meta-analysis of randomised sham/placebo-controlled trials. Complement Ther Med 2023;75:102956. PubMed
Yan Y, López-Alcalde J, Zhang L, Siebenhüner AR, Witt CM, Barth J. Acupuncture for the prevention of chemotherapy-induced nausea and vomiting in cancer patients: A systematic review and meta-analysis. Cancer Med 2023;12(11):12504-12517. PubMed
Park EY, Cho JH, Lee SH, Kim KW, Ha IH, Lee YJ. Is acupuncture an effective treatment for temporomandibular disorder?: A systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore) 2023;102(38):e34950. PubMed
Hyun MH, Kim JH, Jang JW, et al. Risk of Hepatitis C Virus Transmission through acupuncture: A systematic review and meta-analysis. Korean J Gastroenterol 2023;82(3):127-136. PubMed
Lin J, Kong Y, Chen H, Ding X, Zhou W. Effects of acupuncture on sleep quality in patients with Parkinson's disease: A systematic review and meta-analysis. Clin Rehabil 2024;38(4):478-496. PubMed
Yu Y, Hu G, Yang X, Yin Y, Tong K, Yu R. A strategic study of acupuncture for diabetic kidney disease based on meta-analysis and data mining. Front Endocrinol (Lausanne) 2024;15:1273265. PubMed
Wang Y, Peng J, Xiao L, et al. Effectiveness of acupuncture combined with artificial tears in managing dry eye syndrome: A systematic review and meta-analysis. Medicine (Baltimore) 2024;103(1):e36374. PubMed
Ghanad E, Reissfelder C, Yang C. Acupuncture-induced hemothorax with hypovolemic shock: A case report. J Integr Complement Med 2024;30(3):310-312. PubMed
Chon SH. Intrathoracic migration of an acupuncture needle causing chronic empyema: a case report. Acupunct Med 2024;42(1):54-55. PubMed
Li S, Sun S, Wang G. Endoscopic treatment for a hematoma-mediated colon obstruction caused by acupuncture: A rare case report. Endoscopy. 2023;55(S 01):E713-E714. PubMed
Su Q, Wang L, Yu H, Li H, Zou D, Ni X. Chinese herbal medicine and acupuncture for insomnia in stroke patients: A systematic review and meta-analysis of randomised controlled trials. Sleep Med 2024;120:65-84. PubMed
Yeh ML, Liao RW, Yeh PH, Lin CJ, Wang YJ. Acupuncture-related interventions improve chemotherapy-induced peripheral neuropathy: A systematic review and network meta-analysis. BMC Complement Med Ther 2024;24(1):310. PubMed
Bao QN, Yin ZH, Zhou YF, et al. Efficacy and safety of acupuncture for postpartum hypogalactia: A systematic review and meta-analysis of randomized controlled trials. PLoS One 2024;19(6):e0303948. PubMed
Cao H, Li H, Lin G, et al. The clinical value of acupuncture for women with premature ovarian insufficiency: a systematic review and meta-analysis of randomized controlled trials. Front Endocrinol (Lausanne) 2024;15:1361573. PubMed
Lu L, Chen C, Chen Y, et al. Effect of acupuncture for methadone reduction : A randomized clinical trial. Ann Intern Med 2024;177(8):1039-1047. PubMed
Liu L, Chen Q, Zhao L, et al. Acupuncture plus topiramate placebo versus topiramate plus sham acupuncture for the preventive treatment of chronic migraine: A single-blind, double-dummy, randomized controlled trial. Cephalalgia 2024;44(6):3331024241261080. PubMed
Yuan J, Goh AGW, Mohamed Shah MTB. Bilateral facet joint septic arthritis induced by acupuncture: A case report highlighting diagnostic challenges and the importance of early intervention. Am J Case Rep 2024;25:e944596. PubMed
Shirota S, Oka S, Terasawa Y, Nishioka H. Multiple embedded acupuncture needles removed using image-guided percutaneous approach. BMJ Case Rep 2024;17(6):e260303. PubMed
Seah EZ. Traditional Chinese acupuncture causing acute hemoperitoneum from direct liver injury. J Radiol Case Rep. 2023 Aug 31;17(8):15-20. doi: 10.3941/jrcr.v17i8.5100. PubMed
Yang R, Hu Y, Liu S, Wang H. Subcutaneous and paravertebral abscess following massage and acupuncture with cupping: A case report and literature review. Asian J Surg. 2024 Jun;47(6):2632-2634. doi: 10.1016/j.asjsur.2023.08.210. Epub 2023 Sep 7. PubMed
Liu Y, Wang Y, Mi C, Wang Z, Han Y, Qi X, Ding X. Efficacy of acupuncture-related therapy for migraine: A systematic review and network meta-analysis. J Pain Res. 2024 Mar 15;17:1107-1132. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Acupuncture While Taking Tenapanor Hydrochloride: Common Questions

Is it safe to have Acupuncture while taking Tenapanor Hydrochloride?

We do not list a known interaction between Acupuncture and Tenapanor Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Acupuncture and Tenapanor Hydrochloride have any of the same side effects?

Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Does Tenapanor Hydrochloride interact with any supplements?

Yes. Tenapanor Hydrochloride has documented interactions with 138 supplements in our database — Acupuncture is not one of them. The Tenapanor Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.