Drug & supplement interaction

Amaranth + Amylase, Lipase, Protease

Amylase, Lipase, Protease brand names: Pangestyme MT 16, Pangestyme CN 10, Pangestyme CN 20, Pangestyme EC, Pangestyme UL 12, and others.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Amaranth and Amylase, Lipase, Protease in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Amaranth and Amylase, Lipase, Protease

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Amylase, Lipase, Protease and Amaranth in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Amaranth at all — not against Amylase, Lipase, Protease, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Amaranth safety at a glance

Amaranth overall Use caution Generally safe as a food, but medicinal supplement doses are not well studied.
Pregnancy Use caution Food amounts are likely fine, but avoid concentrated medicinal doses due to lack of safety data.
Breastfeeding Use caution Food amounts are likely fine, but supplement-level doses have not been studied.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Amylase, Lipase, Protease and Amaranth? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Amylase, Lipase, Protease’s Own FDA Label Lists

This is not an interaction — none of it involves Amaranth. These are the most notable effects listed in the ADVERSE REACTIONS section of Amylase, Lipase, Protease’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • A bowel blockage Worth acting on
  • Wheezing Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Bleeding or bruising Worth acting on
  • An allergic reaction Worth acting on
  • Bloating or gas
  • Blurred vision
  • Cough
  • Muscle pain

Showing the 10 most notable of 16 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Amylase, Lipase, Protease. Read the label on DailyMed › Amaranth’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Amaranth side to compare — that is a limit of the record, not a statement that Amaranth has no side effects.

Everything else you take

See Every Supplement That Interacts With Amylase, Lipase, Protease

This page covers Amaranth only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amylase, Lipase, Protease page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Amylase, Lipase, Protease page

“Pancreatic enzyme replacements (amylase, lipase, and protease, the Pangestyme brands) only work if the capsules reach your gut and mix with food, and all 17 supplements listed here can interfere with that, so the list deserves real care. Activated charcoal is the one major-rated entry; it soaks up medicines in the digestive tract befor…”

Reviewed by 2 · Jul 18, 2026

Open the Amylase, Lipase, Protease interaction page

One more smart check

Taking Amaranth as Part of a Dietary Supplement Product? Check It for Interactions

We hold 404 real supplement products containing Amaranth, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Amaranth. Even though Amaranth itself has no known interaction with Amylase, Lipase, Protease, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Amaranth and Amylase, Lipase, Protease Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Amaranth
Top half

#414 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Amylase, Lipase, Protease
Top 10%

#261 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Amaranth reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Amaranth and Amylase, Lipase, Protease records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Amaranth

What is Amaranth?

Amaranth
  • Nutrition and as a gluten-free grain
  • High cholesterol
  • Diarrhea and digestive upset
  • Mouth and throat irritation (gargle)
  • Wound and skin care (traditional)

Amaranth is a nutritious plant whose seeds are used as a gluten-free pseudocereal and whose leaves are eaten as a vegetable. It is generally considered safe as a food, but evidence for its medicinal benefits (such as lowering cholesterol) is limited and mostly preliminary. Talk to your pharmacist or doctor before using concentrated supplements.

Amaranthus spp. · Amaranthaceae · Leaves, seeds, seed oil, roots, and whole plant · Seeds and flour (pseudocereal), leafy vegetable, seed oil, capsules, powders, and teas

An interaction check asks whether these two react with each other — it does not ask whether Amaranth is a good idea for someone in your situation. Here is what our Amaranth record says about it on its own.

Amaranth: dosing

There is no established standardized medicinal dose for amaranth. As a food, it is simply prepared and eaten like other grains or leafy vegetables.If you choose a supplement, oil, or capsule, follow the directions on the product label, since the amount of active ingredients can vary widely between products.

From our Amaranth monograph — the full record covers uses, side effects and every documented interaction.

Read the full Amaranth monograph & all interactions
Medication

About Pancrelipase

What Is Pancrelipase Used For?

Brand names: Pangestyme MT 16, Pangestyme CN 10, Pangestyme CN 20, Pangestyme EC, Pangestyme UL 12, Pangestyme UL 18, Pangestyme UL 20, Pancrelipase, Pancrelipase 10,000, Lipram 10,000, Pancrecarb Ms-4, Ku-Zyme, Kutrase, Digepepsin, Pancrecarb Ms-8, Pancrelipase 16,000, Pancrelipase 20,000, Pancron 20, Festal II, Microspheres, Zymase, Entozyme, Ku-Zyme HP, Protilase, Ilozyme, Plaretase, Ultresa

Pancrelipase is used to treat exocrine pancreatic insufficiency (EPI) — a condition where the pancreas doesn't produce enough digestive enzymes. Without these enzymes, the body struggles to break down and absorb nutrients from food.

It is indicated for adults with EPI caused by chronic pancreatitis (long-term pancreas inflammation) or pancreatectomy (surgical removal of the pancreas, in whole or in part). It is also used in people with cystic fibrosis who develop EPI.

See full Pancrelipase drug information
Keep checking

Other Drugs & Amaranth

Browse every other medication we’ve checked against Amaranth — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Amaranth against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Amaranth list.

See the full Amaranth interactions page
See every supplement checked against Amylase, Lipase, Protease, ranked by severity
Evidence & sources

Amaranth References

The 6 references that drive our Amaranth monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Maier SM, Turner ND, Lupton JR. Serum lipids in hypercholesterolemic men and women consuming oat bran and amaranth products. Cereal Chem 2000:77;297-302. DOI
  2. Martirosyan, D. M., Miroshnichenko, L. A., Kulakova, S. N., Pogojeva, A. V., and Zoloedov, V. I. Amaranth oil application for coronary heart disease and hypertension. Lipids Health Dis. 2007;6:1.
  3. Cherkas A, Zarkovic K, Cipak Gasparovic A, et al. Amaranth oil reduces accumulation of 4-hydroxynonenal-histidine adducts in gastric mucosa and improves heart rate variability in duodenal peptic ulcer patients undergoing Helicobacter pylori eradication. F
  4. Dus-Zuchowska M, Walkowiak J, Morawska A, et al. Amaranth oil increases total and LDL cholesterol levels without influencing early markers of atherosclerosis in an overweight and obese population: A randomized double-blind cross-over study in comparison w
  5. Orsango AZ, Loha E, Lindtjørn B, Engebretsen IMS. Efficacy of processed amaranth-containing bread compared to maize bread on hemoglobin, anemia and iron deficiency anemia prevalence among two-to-five year-old anemic children in Southern Ethiopia: A cluste
  6. Moszak M, Zawada A, Juchacz A, Grzymislawski M, Bogdanski P. Comparison of the effect of rapeseed oil or amaranth seed oil supplementation on weight loss, body composition, and changes in the metabolic profile of obese patients following 3-week body mass

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Amaranth and Amylase, Lipase, Protease Together: Common Questions

Is it safe to take Amaranth with Amylase, Lipase, Protease?
We do not list a known interaction between Amaranth and Amylase, Lipase, Protease. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Amylase, Lipase, Protease interact with any supplements?
Yes. Amylase, Lipase, Protease has documented interactions with 17 supplements in our database — Amaranth is not one of them. The Amylase, Lipase, Protease interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Amaranth monograph Uses, safety profile, and every drug interaction in one place Pancrelipase drug information The full plain-English guide to this medication Amylase, Lipase, Protease supplement interactions Every supplement checked against Amylase, Lipase, Protease, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Amylase, Lipase, Protease and Amaranth?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.