Drug & supplement interaction

Anti-inflammatory Diet + Lidocaine

Lidocaine brand names: Xylocaine, Dilocaine, Lidoject-1, Xylocaine MPF, Nervocaine, and others.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Anti-inflammatory Diet and Lidocaine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Anti-inflammatory Diet and Lidocaine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lidocaine and Anti-inflammatory Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Anti-inflammatory Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Anti-inflammatory Diet at all — not against Lidocaine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Anti-inflammatory Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Anti-inflammatory Diet safety at a glance

Anti-inflammatory... overall Generally safe For most people, this is a balanced, nutritious eating pattern that is safe to follow.
Pregnancy Use caution Generally healthy during pregnancy, but discuss nutrient needs and any restrictive changes with your doctor.
Breastfeeding Use caution A balanced version is usually fine, but avoid overly restrictive plans and check with your provider.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lidocaine and Anti-inflammatory Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Anti-inflammatory Diet and Lidocaine May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so following Anti-inflammatory Diet while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Nausea reported in 5.2% of FDA reports for Lidocaine Additional detail

    Anti-inflammatory Diet

    “Gastrointestinal symptoms such as upset stomach with diarrhea, gas, heartburn, and nausea have been reported.”

    Anti-inflammatory Diet · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 104690. Vadell AKE, Bärebring L, Hulander E, et al. Anti-inflammatory diet in rheumatoid arthritis (ADIRA)-a randomized, controlled crossover trial indicating effects on disease activity. Am J Clin Nutr. 2020;111(6):1203-1213.

    Lidocaine

    Listed in the ADVERSE REACTIONS section of the FDA label for Lidocaine, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Anti-inflammatory Diet but not commonly for Lidocaine: stomach upset, heartburn and diarrhea.

Effects for Lidocaine come from the ADVERSE REACTIONS section of its FDA label; effects for Anti-inflammatory Diet come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 96,036 voluntary FDA FAERS reports for Lidocaine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Lidocaine

This page covers Anti-inflammatory Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lidocaine page lists 145 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Fever Bark (major), Grapefruit (major), St. John's Wort (major), 1,3-dmaa (moderate) and Acacia Rigidula (moderate).

By severity: 3 major · 111 moderate · 31 minor.

From our pharmacist’s overview on the Lidocaine page

“Lidocaine (Xylocaine) deserves genuine care on this page, and I would learn its three major-rated entries first. Grapefruit and St.”

Reviewed by 2 · Jul 18, 2026

Open the Lidocaine interaction page

How much people look this up

Where Anti-inflammatory Diet and Lidocaine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Anti-inflammatory Diet
Steady interest

#1,369 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lidocaine
Top 25%

#586 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Anti-inflammatory Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Anti-inflammatory Diet and Lidocaine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Anti-inflammatory Diet

What is Anti-inflammatory Diet?

  • Joint pain and arthritis
  • Heart health
  • Reducing chronic inflammation
  • Weight management
  • General wellness and disease prevention

An anti-inflammatory diet is an eating pattern that emphasizes vegetables, fruits, whole grains, beans, nuts, fish, and olive oil while limiting processed foods, added sugar, and refined carbohydrates. It is generally safe and broadly healthy, and some evidence links it to lower inflammation markers and better heart and joint health, though it is a supportive lifestyle approach rather than a cure. Talk with your doctor or a registered dietitian before making major changes, especially if you have a medical condition.

Whole-food eating pattern (meal plans, recipes, dietary guidelines)

An interaction check asks whether these two react with each other — it does not ask whether Anti-inflammatory Diet is a good idea for someone in your situation. Here is what our Anti-inflammatory Diet record says about it on its own.

Anti-inflammatory Diet: dosing

There is no set "dose" for an anti-inflammatory diet because it is an eating pattern, not a supplement. A common approach is to fill most of your plate with vegetables, fruits, whole grains, and beans; choose fish, nuts, and olive oil as main fat and protein sources; and limit sugary drinks, refined grains, processed meats, and ultra-processed snacks.If you buy any branded "anti-inflammatory" supplements or meal products, follow the label and do not assume more is better. A registered dietitian can help tailor the plan to your needs, and your pharmacist or doctor can help if you have health conditions.

From our Anti-inflammatory Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Anti-inflammatory Diet monograph & all interactions
Medication

About Lidocaine Transdermal Patch

What Is Lidocaine Transdermal Patch Used For?

Brand names: Xylocaine, Dilocaine, Lidoject-1, Xylocaine MPF, Nervocaine, Lidoject-2, Duo-Trach Kit, Octocaine, Lidoderm, Ztlido

Lidocaine skin patches are applied directly to the painful area to treat post-herpetic neuralgia (PHN) — the persistent burning or aching nerve pain that can remain after a shingles outbreak.

Lidoderm (lidocaine patch 5%) and ZTlido (lidocaine topical system 1.8%) are both indicated for this use in adults. Note that despite their different strengths, one ZTlido topical system provides equivalent lidocaine exposure to one Lidoderm patch.

Most-Reported Side Effects for Lidocaine

From FAERS, the FDA’s public side-effect reporting system (96,036 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 4,961 reports
Fatigue 4,867 reports
Headache 4,439 reports
Product quality issue 3,920 reports
Dyspnea 3,658 reports
See full Lidocaine Transdermal Patch drug information
Keep checking

Other Drugs & Anti-inflammatory Diet

Browse every other medication we’ve checked against Anti-inflammatory Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Anti-inflammatory Diet References

The 1 references that drive our Anti-inflammatory Diet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Vadell AKE, Bärebring L, Hulander E, et al. Anti-inflammatory diet in rheumatoid arthritis (ADIRA)-a randomized, controlled crossover trial indicating effects on disease activity. Am J Clin Nutr. 2020;111(6):1203-1213.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Anti-inflammatory Diet While Taking Lidocaine: Common Questions

Is it safe to follow Anti-inflammatory Diet while taking Lidocaine?
We do not list a known interaction between Anti-inflammatory Diet and Lidocaine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Anti-inflammatory Diet and Lidocaine have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Lidocaine interact with any supplements?
Yes. Lidocaine has documented interactions with 145 supplements in our database — Anti-inflammatory Diet is not one of them. The Lidocaine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Lidocaine and Anti-inflammatory Diet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.