Arum + Pimecrolimus
Pimecrolimus brand name: Elidel.
We found no known interaction between Arum and Pimecrolimus in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Arum and Pimecrolimus
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Pimecrolimus and Arum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Arum safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Pimecrolimus
Interactions in our licensed database are recorded against drug classes, not just single drug names. Pimecrolimus is filed under a single classification — topical drugs. Arum has documented interactions with 1 drug class — the most serious being iron (minor) — and none of Pimecrolimus’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Arum Does Interact With Other Medications
Arum has 1 minor known drug interaction in our database — Pimecrolimus isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Arum
We haven’t checked that one against Arum yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Arum. Pick one to open its full report.
Arum in Pregnancy & Breastfeeding
When used orally because of its toxicity; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Pimecrolimus
This page covers Arum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pimecrolimus page lists 3 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).
By severity: 2 moderate · 1 minor.
From our pharmacist’s overview on the Pimecrolimus page
“Pimecrolimus (Elidel) is an eczema cream, applied to the skin rather than swallowed, so its supplement interactions are few and they follow one pattern. All three ingredients on file are also used topically, and the two rated moderate, DMSO and turpentine oil, may pull more of the drug through the skin, amplifying both its benefit and…”
Reviewed by 2 · Jul 18, 2026
Where Arum and Pimecrolimus Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#693 of 1,452 supplements looked up here in the last 7 days
#1,669 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Arum reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Arum and Pimecrolimus records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Arum
What is Arum?
- Coughs and chest congestion
- Sore throat
- Promoting sweating (diaphoretic)
- Skin and wart remedies (topical folk use)
- Digestive complaints
Arum is a traditional European plant whose root has been used in folk medicine, but there is essentially no reliable human research to support any health benefit. The raw plant is toxic and irritating because of calcium oxalate crystals, so it should not be eaten or used casually. We do not recommend using Arum as a supplement, especially during pregnancy or breastfeeding.
Arum maculatum · Araceae · Root (tuber), and sometimes leaves · Dried root preparations, tinctures, and traditional folk remedies
An interaction check asks whether these two react with each other — it does not ask whether Arum is a good idea for someone in your situation. Here is what our Arum record says about it on its own.
Arum: dosing
There is no established or standardized safe dose for Arum. Because the plant is toxic and human research is lacking, no trustworthy dosing guidelines exist.We do not recommend taking Arum. If you encounter a product that contains it, do not use it without first checking with a pharmacist or doctor, and never prepare or eat the raw plant yourself.
From our Arum monograph — the full record covers uses, side effects and every documented interaction.
About Pimecrolimus Topical
What Is Pimecrolimus Topical Used For?
Brand name: Elidel
Pimecrolimus cream 1% is used to treat mild to moderate atopic dermatitis (eczema) in adults and children aged 2 and older. It is a second-line option — meaning it's tried when other topical prescription treatments haven't worked well enough, or when those treatments aren't a good fit.
It is intended for short-term and non-continuous use only, applied only to the affected areas. It is not approved for use in children under 2 years of age, and it should only be used in people with healthy immune systems.
Most-Reported Side Effects for Pimecrolimus
From FAERS, the FDA’s public side-effect reporting system (1,704 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Arum
Browse every other medication we’ve checked against Arum — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
No interaction 2,828 drugs checked — show the list
We also checked Arum against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Ivermectin ›
- Testosterone ›
- Losartan Potassium ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Escitalopram ›
- Rivaroxaban ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tirzepatide ›
- Methamphetamine ›
- Tadalafil ›
- Ibuprofen ›
- Valacyclovir ›
- Warfarin Sodium ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Amitriptyline ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Amphetamine ›
- Bupropion ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Quetiapine ›
- Naproxen ›
- Clonazepam ›
- Omeprazole ›
- Duloxetine ›
- Letrozole ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Arum list.
Arum References
The 3 references that drive our Arum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Mrvos, R., Dean, B. S., and Krenzelok, E. P. Philodendron/dieffenbachia ingestions: are they a problem? J Toxicol Clin Toxicol 1991;29(4):485-491. PubMed
- Prakash Raju KNJ, Goel K, Anandhi D, Pandit VR, Surendar R, Sasikumar M. Wild tuber poisoning: Arum maculatum - A rare case report. Int J Crit Illn Inj Sci. 2018;8(2):111-114. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Arum and Pimecrolimus Together: Common Questions
Is it safe to take Arum with Pimecrolimus?
How was the Arum and Pimecrolimus combination checked?
Does Arum interact with any other medications?
Does Pimecrolimus interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Pimecrolimus and Arum?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.