Drug & supplement interaction

Asparagus Racemosus + Quinethazone

Quinethazone brand name: Hydromox.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

Asparagus Racemosus has a moderate interaction with Quinethazone. Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Asparagus Racemosus and Quinethazone

Here is the interaction we found between these two, with the evidence behind it.

Moderate

DIURETIC DRUGS

Why this applies to Quinethazone

Quinethazone falls under DIURETIC DRUGS — the group Asparagus Racemosus interacts with.

Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Quinethazone is a thiazide-type water pill that helps your body get rid of extra fluid and salt, which is how it lowers blood pressure and reduces swelling. The concern here is simple: shatavari (asparagus racemosus) may also have a mild water-pill effect of its own. So in theory, stacking the two could push fluid and electrolyte loss a little further than the medication alone.

Here's my honest take. This interaction comes only from animal studies using high doses, and it has not been shown in people, so I wouldn't lose sleep over it. Still, if you do combine them, watch for signs of going too far: dizziness, lightheadedness when standing, leg cramps, or feeling weak or tired, which can signal low potassium or sodium. Please run it by your pharmacist or doctor first, especially if you already have low electrolytes.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Satish Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59(1):3-6.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Asparagus Racemosus Also Interacts With Other Medications

Asparagus Racemosus has 75 moderate known drug interactions in our database — the Quinethazone one above is one of them. If you take anything else, check it against the full list below.

Moderate 75 No known interaction 2,755 (incl. Quinethazone)
Taking anything else?

Check Another of Your Medications Against Asparagus Racemosus

Covers the 2,830 medications we’ve checked against Asparagus Racemosus. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Quinethazone

This page covers Asparagus Racemosus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Quinethazone page lists 217 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Lithium (major) and Oleander (major).

By severity: 7 major · 186 moderate · 24 minor.

From our pharmacist’s overview on the Quinethazone page

“Quinethazone (Hydromox) is a thiazide-type water pill for high blood pressure and fluid buildup, and its supplement list calls for genuine care, starting with the seven entries rated major among the 217 on file. Most of the 186 moderate interactions come from herbs and foods that also lower blood pressure, so stacking them can drop you…”

Reviewed by 2 · Jul 18, 2026

Open the Quinethazone interaction page

One more smart check

Taking Asparagus Racemosus as Part of a Dietary Supplement Product? Check It for Interactions

We hold 330 real supplement products containing Asparagus Racemosus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Asparagus Racemosus. Your product may carry other ingredients that interact with Quinethazone too, on top of Asparagus Racemosus — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Asparagus Racemosus and Quinethazone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Asparagus Racemosus
Top 25%

#357 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Quinethazone
Top half

#1,198 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Asparagus Racemosus

What is Asparagus Racemosus?

Asparagus Racemosus
  • Women's reproductive health
  • Promoting breast milk supply
  • Digestive complaints
  • General tonic and stress support
  • Menopausal symptoms

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limited and preliminary, so benefits are not well proven. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have hormone-sensitive conditions.

Read the full Asparagus Racemosus monograph & all interactions
Keep checking

Other Drugs & Asparagus Racemosus

Browse every other medication we’ve checked against Asparagus Racemosus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
75Moderate
0Minor
2,754No known interaction
75 Moderate 2,754 No interaction
Moderate

75 interactions

Showing 60 of 75 moderate interactions — see all 75 on the Asparagus Racemosus page.

No interaction 2,754 drugs checked — show the list

We also checked Asparagus Racemosus against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,754 medications checked with no known interaction — see the full Asparagus Racemosus list.

See the full Asparagus Racemosus interactions page
See every supplement checked against Quinethazone, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Asparagus Racemosus monograph › Uses, safety, and every drug interaction in one place Quinethazone supplement interactions › Every supplement checked against Quinethazone, ranked by severity Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Asparagus Racemosus and Quinethazone Together: Common Questions

Can you take Asparagus Racemosus with Quinethazone?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Asparagus Racemosus and Quinethazone interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Quinethazone and Asparagus Racemosus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.