Drug & supplement interaction

Asparagus Racemosus + Amitriptyline

Amitriptyline brand name: Elavil.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Asparagus Racemosus and Amitriptyline in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Asparagus Racemosus and Amitriptyline

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Amitriptyline and Asparagus Racemosus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Asparagus Racemosus safety at a glance

Asparagus Racemosu... overall Use caution Generally considered well tolerated in traditional use, but high-quality safety data are limited.
Pregnancy Avoid Safety during pregnancy is not well established, so it is best avoided unless a doctor advises otherwise.
Breastfeeding Use caution It is traditionally used to support milk supply, but reliable safety data are lacking, so use only under professional guidance.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Amitriptyline and Asparagus Racemosus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Amitriptyline

Interactions in our licensed database are recorded against drug classes, not just single drug names. Amitriptyline is filed under 15 classifications — including tricyclic antidepressants (tcas), antidepressant drugs, cytochrome p450 2c19 (cyp2c19) substrates. Asparagus Racemosus has documented interactions with 2 drug classes — the most serious being diuretic drugs (moderate) and lithium (moderate) — and none of Amitriptyline’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Asparagus Racemosus Does Interact With Other Medications

Asparagus Racemosus has 76 moderate known drug interactions in our database — Amitriptyline isn’t one of them. If you take anything else, check it against the full list below.

Moderate 76 No known interaction 2,754 (incl. Amitriptyline)
Taking anything else?

Check Another of Your Medications Against Asparagus Racemosus

Covers the 2,830 medications we’ve checked against Asparagus Racemosus. Pick one to open its full report.

What to actually watch for

What Amitriptyline’s Own FDA Label Lists

This is not an interaction — none of it involves Asparagus Racemosus. These are the most notable effects listed in the ADVERSE REACTIONS section of Amitriptyline’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Dependence or withdrawal symptoms Worth acting on
  • Serotonin syndrome Worth acting on
  • A bowel blockage Worth acting on
  • Trouble passing urine Worth acting on
  • Unsteadiness Worth acting on
  • A heart attack Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Fainting Worth acting on

Showing the 10 most notable of 51 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Amitriptyline. Read the label on DailyMed › Where a percentage is shown, it is the share of 17,459 voluntary FDA FAERS reports for Amitriptyline that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Asparagus Racemosus’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Asparagus Racemosus side to compare — that is a limit of the record, not a statement that Asparagus Racemosus has no side effects.

From our Q&A

Questions About Asparagus Racemosus or Amitriptyline

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Asparagus Racemosus or Amitriptyline, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Amitriptyline

This page covers Asparagus Racemosus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amitriptyline page lists 296 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), American Hellebore (major), Arsenic (major) and Beer (major).

By severity: 17 major · 228 moderate · 51 minor.

From our pharmacist’s overview on the Amitriptyline page

“Amitriptyline (Elavil), an older antidepressant now often prescribed for nerve pain, migraines, and sleep, is one of the drugs I genuinely want patients to be careful with, and 17 of the 296 supplement and herbal ingredients on this list carry a major rating. Most of the serious ones deepen the drowsiness amitriptyline already causes,…”

Reviewed by 2 · Jul 18, 2026

Open the Amitriptyline interaction page

One more smart check

Taking Asparagus Racemosus as Part of a Dietary Supplement Product? Check It for Interactions

We hold 330 real supplement products containing Asparagus Racemosus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Asparagus Racemosus. Even though Asparagus Racemosus itself has no known interaction with Amitriptyline, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Asparagus Racemosus and Amitriptyline Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Asparagus Racemosus
Top half

#384 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Amitriptyline
Top 5%

#52 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Asparagus Racemosus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Asparagus Racemosus and Amitriptyline records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Asparagus Racemosus

What is Asparagus Racemosus?

Asparagus Racemosus
  • Women's reproductive health
  • Promoting breast milk supply
  • Digestive complaints
  • General tonic and stress support
  • Menopausal symptoms

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limited and preliminary, so benefits are not well proven. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have hormone-sensitive conditions.

Asparagus racemosus · Asparagaceae · Roots (tuberous roots) · Capsules, tablets, powder (churna), liquid extracts, syrups

An interaction check asks whether these two react with each other — it does not ask whether Asparagus Racemosus is a good idea for someone in your situation. Here is what our Asparagus Racemosus record says about it on its own.

Asparagus Racemosus: dosing

There is no official, standardized dose for Asparagus racemosus. Products vary widely in strength and form, from powders to capsules to liquid extracts.The best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Asparagus Racemosus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Asparagus Racemosus monograph & all interactions
Medication

About Amitriptyline

What Is Amitriptyline Used For?

Brand name: Elavil

Amitriptyline HCL and Amitriptyline Hydrochloride tablets are used to relieve symptoms of depression. Depression that originates from within the body (called endogenous depression) tends to respond better than other types of depression.

Most-Reported Side Effects for Amitriptyline

From FAERS, the FDA’s public side-effect reporting system (17,459 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 1,535 reports
Headache 1,476 reports
Fatigue 1,448 reports
Dyspnea 1,442 reports
Dizziness 1,227 reports
See full Amitriptyline drug information
Keep checking

Other Drugs & Asparagus Racemosus

Browse every other medication we’ve checked against Asparagus Racemosus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
76Moderate
0Minor
2,753No known interaction
76 Moderate 2,753 No interaction
Moderate

76 interactions

Showing 60 of 76 moderate interactions — see all 76 on the Asparagus Racemosus page.

No interaction 2,753 drugs checked — show the list

We also checked Asparagus Racemosus against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,753 medications checked with no known interaction — see the full Asparagus Racemosus list.

See the full Asparagus Racemosus interactions page
See every supplement checked against Amitriptyline, ranked by severity
Evidence & sources

Asparagus Racemosus References

The 1 references that drive our Asparagus Racemosus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Satish Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59(1):3-6.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Asparagus Racemosus and Amitriptyline Together: Common Questions

Is it safe to take Asparagus Racemosus with Amitriptyline?
We do not list a known interaction between Asparagus Racemosus and Amitriptyline. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Asparagus Racemosus and Amitriptyline combination checked?
Interactions in our licensed database are recorded against drug classes. Amitriptyline is filed under 15 classifications, and Asparagus Racemosus has documented interactions with 2 drug classes — none of Amitriptyline's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Asparagus Racemosus interact with any other medications?
Yes. Asparagus Racemosus has 76 documented drug interactions in our database — Amitriptyline is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Amitriptyline interact with any supplements?
Yes. Amitriptyline has documented interactions with 296 supplements in our database — Asparagus Racemosus is not one of them. The Amitriptyline interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Asparagus Racemosus monograph Uses, safety profile, and every drug interaction in one place Amitriptyline drug information The full plain-English guide to this medication Amitriptyline supplement interactions Every supplement checked against Amitriptyline, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Amitriptyline and Asparagus Racemosus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.