Drug & supplement interaction

Bayberry + Econazole

Econazole brand name: Spectazole.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Bayberry and Econazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Bayberry and Econazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Econazole and Bayberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Bayberry at all — not against Econazole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Bayberry safety at a glance

Bayberry overall Use caution Limited safety data; large amounts may irritate the stomach and the bark contains compounds of concern.
Pregnancy Possibly Unsafe When used orally or topically because of possible carcinogenic, or mineralocorticoid activities; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or topically because of possible carcinogenic, or mineralocorticoid activities; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Econazole and Bayberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Bayberry Itself Has Been Linked To

This is not an interaction — nothing below involves Econazole. It is the side-effect record for Bayberry on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Bayberry, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on Additional detail

    “Orally, bayberry can cause gastrointestinal irritation, vomiting, and liver damage, possibly due to its tannin content. It can also act as an irritant and sensitizer (6).”

    Bayberry · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  • Vomiting Additional detail

    “Orally, bayberry can cause gastrointestinal irritation and vomiting, possibly due to its tannin content (6).”

    Bayberry · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

Everything above comes from the Natural Medicines adverse-effect record for Bayberry — expand a row for the licensed statement it rests on. We haven’t matched Econazole to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Econazole.

Special populations

Bayberry in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or topically because of possible carcinogenic, or mineralocorticoid activities; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Econazole

This page covers Bayberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Econazole page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 12 minor.

From our pharmacist’s overview on the Econazole page

“Econazole (Spectazole) is an antifungal cream for skin infections like athlete's foot and ringworm, and its interaction list is one to treat with real care. The priority is activated charcoal, the lone major-rated entry, which can soak up medications and lower their levels even when a drug is not taken by mouth.”

Reviewed by 2 · Jul 18, 2026

Open the Econazole interaction page

One more smart check

Taking Bayberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 257 real supplement products containing Bayberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Bayberry. Even though Bayberry itself has no known interaction with Econazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Bayberry and Econazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Bayberry
Top half

#507 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Econazole
Top 25%

#428 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bayberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Bayberry and Econazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Bayberry

What is Bayberry?

Bayberry
  • Diarrhea and digestive upset
  • Sore throat and cold symptoms
  • Gum and mouth rinse (gargle)
  • Skin and wound care
  • General "astringent" tonic

Bayberry is a traditional herb used mainly as an astringent for diarrhea, sore throats, and minor skin or gum problems, but there is very little modern human research to confirm it works. Its bark contains tannins and other compounds that may cause stomach upset and could be harmful in large amounts. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Morella cerifera · Myricaceae · Root bark, leaves, and stem bark; berries (for wax) · Dried root bark, powder, capsules, tea, tincture, and topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Bayberry is a good idea for someone in your situation. Here is what our Bayberry record says about it on its own.

Bayberry: dosing

There is no well-established or standardized dose for bayberry. Because human studies are lacking, no reliable "safe and effective" amount has been set.If you choose to use a bayberry product, follow the directions on the product label and do not exceed the suggested amount.

From our Bayberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Bayberry monograph & all interactions
Medication

About Econazole Topical

What Is Econazole Topical Used For?

Brand name: Spectazole

Econazole nitrate is used to treat interdigital tinea pedis (athlete's foot — the kind that affects the skin between the toes), caused by specific fungi including Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. It is approved for patients 12 years of age and older.

Econazole nitrate cream is also used for tinea cruris (jock itch), tinea corporis (ringworm), tinea versicolor (a patchy skin discoloration caused by yeast), and cutaneous candidiasis (a skin infection caused by Candida yeast).

See full Econazole Topical drug information
Keep checking

Other Drugs & Bayberry

Browse every other medication we’ve checked against Bayberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Bayberry References

The 3 references that drive our Bayberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Bayberry and Econazole Together: Common Questions

Is it safe to take Bayberry with Econazole?
We do not list a known interaction between Bayberry and Econazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Econazole interact with any supplements?
Yes. Econazole has documented interactions with 20 supplements in our database — Bayberry is not one of them. The Econazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Econazole and Bayberry?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.