Drug & supplement interaction

Beeswax + Ofatumumab

Ofatumumab brand name: Kesimpta.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Beeswax and Ofatumumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Beeswax and Ofatumumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ofatumumab and Beeswax in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Beeswax at all — not against Ofatumumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Beeswax safety at a glance

Beeswax overall Use caution Topical use is generally well tolerated, but oral use is less studied and people with bee product allergies should be careful.
Pregnancy Use caution Topical use is likely fine, but oral medicinal use during pregnancy has not been well studied, so check with your doctor.
Breastfeeding Use caution Topical use is likely fine, but there is not enough information on oral medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ofatumumab and Beeswax? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Beeswax Itself Has Been Linked To

This is not an interaction — nothing below involves Ofatumumab. It is the side-effect record for Beeswax on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Beeswax, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on Additional detail

    “Orally, beeswax is well tolerated. Allergic reactions to beeswax are possible in some patients (11).

    Topically, beeswax may cause allergic contact dermatitis. In most cases, this reaction is likely caused by the propolis component of beeswax.”

    Beeswax · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 11. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
    2. 55245. Abdulrhman M., El Barbary N. S., Ahmed Amin D., and Saeid Ebrahim R. Honey and a mixture of honey, beeswax, and olive oil-propolis extract in treatment of chemotherapy-induced oral mucositis: a randomized controlled pilot study. Pediatr Hematol Oncol 2012 PubMed
    3. 102517. Nyman GSA, Tang M, Inerot A, Osmancevic A, Malmberg P, Hagvall L. Contact allergy to beeswax and propolis among patients with cheilitis or facial dermatitis. Contact Dermatitis 2019;81(2):110-6. PubMed

    “Orally, beeswax may cause allergic reactions (11). Topically, beeswax may cause allergic contact dermatitis. In most cases, this reaction is likely caused by the propolis component of beeswax.”

    Beeswax · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 11. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
    2. 102517. Nyman GSA, Tang M, Inerot A, Osmancevic A, Malmberg P, Hagvall L. Contact allergy to beeswax and propolis among patients with cheilitis or facial dermatitis. Contact Dermatitis 2019;81(2):110-6. PubMed
  • A skin rash Additional detail

    Recorded for Beeswax in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

Everything above comes from the Natural Medicines adverse-effect record for Beeswax — expand a row for the licensed statement it rests on. We haven’t matched Ofatumumab to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Ofatumumab.

Everything else you take

See Every Supplement That Interacts With Ofatumumab

This page covers Beeswax only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ofatumumab page lists 53 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Active Hexose Correlated Compound (ahcc) (moderate), Alfalfa (moderate), American Ginseng (moderate), Andrographis (moderate) and Ashwagandha (moderate).

By severity: 52 moderate · 1 minor.

From our pharmacist’s overview on the Ofatumumab page

“Kesimpta (ofatumumab) treats multiple sclerosis by deliberately quieting part of the immune system, and all 53 supplements on this page raise the same worry from the opposite direction. Each is thought to stimulate immune activity, which could in theory blunt what the drug is trying to do.”

Reviewed by 2 · Jul 18, 2026

Open the Ofatumumab interaction page

One more smart check

Taking Beeswax as Part of a Dietary Supplement Product? Check It for Interactions

We hold 34 real supplement products containing Beeswax, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Beeswax. Even though Beeswax itself has no known interaction with Ofatumumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Beeswax and Ofatumumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Beeswax
Top half

#533 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ofatumumab
Steady interest

#1,909 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Beeswax reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Beeswax and Ofatumumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Beeswax

What is Beeswax?

Beeswax
  • Skin protection and moisturizing
  • Anal fissures and hemorrhoids
  • High cholesterol (oral fatty alcohols)
  • Minor burns and wounds
  • Diaper rash

Beeswax is a natural wax made by honey bees and is most widely and safely used in topical products to soothe and protect the skin. There is some preliminary research on beeswax-derived fatty alcohols for cholesterol and on beeswax mixtures for skin and stomach conditions, but the evidence is limited. It is generally considered safe on the skin for most people, while oral uses are less well studied.

Wax produced by honey bees (Apis mellifera) to build honeycombs · Topical balms, ointments, lip balms, creams, candles; sometimes in oral mixtures and food-grade coatings

An interaction check asks whether these two react with each other — it does not ask whether Beeswax is a good idea for someone in your situation. Here is what our Beeswax record says about it on its own.

Beeswax: dosing

There is no standardized medicinal dose for beeswax. The amount in a product depends on whether it is a balm, ointment, cosmetic, or oral mixture, and on the other ingredients used.For topical products, follow the directions on the label and apply a thin layer to the affected area.

From our Beeswax monograph — the full record covers uses, side effects and every documented interaction.

Read the full Beeswax monograph & all interactions
Medication

About Ofatumumab Injection (Multiple Sclerosis)

What Is Ofatumumab Injection (Multiple Sclerosis) Used For?

Brand name: Kesimpta

Kesimpta is used to treat relapsing forms of multiple sclerosis (MS) in adults. This includes clinically isolated syndrome (a first MS episode), relapsing-remitting MS (the most common form, with flares followed by recovery periods), and active secondary progressive MS (when the disease slowly worsens but still has active flares).

It is designed to reduce relapses and slow disease activity by targeting certain immune cells believed to drive MS damage.

Most-Reported Side Effects for Ofatumumab

From FAERS, the FDA’s public side-effect reporting system (33,037 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 5,534 reports
Headache 4,633 reports
Fever 3,579 reports
Chills 3,483 reports
Influenza like illness 2,900 reports
See full Ofatumumab Injection (Multiple Sclerosis) drug information
Keep checking

Other Drugs & Beeswax

Browse every other medication we’ve checked against Beeswax — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Beeswax against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Beeswax list.

See the full Beeswax interactions page
See every supplement checked against Ofatumumab, ranked by severity
Evidence & sources

Beeswax References

The 9 references that drive our Beeswax monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Al-Waili, N. S. An alternative treatment for pityriasis versicolor, tinea cruris, tinea corporis and tinea faciei with topical application of honey, olive oil and beeswax mixture: an open pilot study. Complement Ther Med 2004;12(1):45-47. PubMed
  3. Al-Waili, N. S. Clinical and mycological benefits of topical application of honey, olive oil and beeswax in diaper dermatitis. Clin Microbiol.Infect. 2005;11(2):160-163. PubMed
  4. Al-Waili, N. S., Saloom, K. S., Al-Waili, T. N., and Al-Waili, A. N. The safety and efficacy of a mixture of honey, olive oil, and beeswax for the management of hemorrhoids and anal fissure: a pilot study. ScientificWorldJournal 2006;6:1998-2005. PubMed
  5. Abdulrhman M., El Barbary N. S., Ahmed Amin D., and Saeid Ebrahim R. Honey and a mixture of honey, beeswax, and olive oil-propolis extract in treatment of chemotherapy-induced oral mucositis: a randomized controlled pilot study. Pediatr Hematol Oncol 2012 PubMed
  6. Gümüs K, Özlü ZK. The effect of a beeswax, olive oil and Alkanna tinctorial (L.) Tausch mixture on burn injuries: An experimental study with a control group. Complement Ther Med. 2017;34:66-73.
  7. Lewis PA, Wright K, Webster A, et al. A randomized controlled pilot study comparing aqueous cream with a beeswax and herbal oil cream in the provision of relief from postburn pruritus. J Burn Care Res 2012;33(4):e195-200.
  8. Nyman GSA, Tang M, Inerot A, Osmancevic A, Malmberg P, Hagvall L. Contact allergy to beeswax and propolis among patients with cheilitis or facial dermatitis. Contact Dermatitis 2019;81(2):110-6. PubMed
  9. Koukourakis G, Pissakas G, Ganos CG, Sivolapenko G, Kardamakis D. Effectiveness and tolerability of natural herbal formulations in the prevention of radiation-induced skin toxicity in patients undergoing radiotherapy. Int J Low Extrem Wounds 2020:15347346 PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Beeswax and Ofatumumab Together: Common Questions

Is it safe to take Beeswax with Ofatumumab?
We do not list a known interaction between Beeswax and Ofatumumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Ofatumumab interact with any supplements?
Yes. Ofatumumab has documented interactions with 53 supplements in our database — Beeswax is not one of them. The Ofatumumab interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Beeswax monograph Uses, safety profile, and every drug interaction in one place Ofatumumab Injection (Multiple Sclerosis) drug information The full plain-English guide to this medication Ofatumumab supplement interactions Every supplement checked against Ofatumumab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 9 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ofatumumab and Beeswax?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.