Drug & supplement interaction

Butylated Hydroxytoluene (bht) + Mobocertinib Succinate

Mobocertinib Succinate brand name: Exkivity.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Butylated Hydroxytoluene (bht) and Mobocertinib Succinate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Interaction report

Butylated Hydroxytoluene (bht) and Mobocertinib Succinate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mobocertinib Succinate and Butylated Hydroxytoluene (bht) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Butylated Hydroxytoluene (bht) at all — not against Mobocertinib Succinate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Butylated Hydroxytoluene (bht) safety at a glance

Butylated Hydroxyt... overall Use caution Approved as a food preservative in small amounts, but using concentrated BHT as a supplement is not well studied and may be harmful.
Pregnancy Likely Safe When used orally as a food additive. Read the full pregnancy detail
Breastfeeding Likely Safe When used orally as a food additive. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mobocertinib Succinate and Butylated Hydroxytoluene (bht)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Butylated Hydroxytoluene (bht) Itself Has Been Linked To

This is not an interaction — nothing below involves Mobocertinib Succinate. It is the side-effect record for Butylated Hydroxytoluene (bht) on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Butylated Hydroxytoluene (bht), this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Fainting / Confusion Worth acting on Additional detail

    “Orally, BHT can cause severe gastritis characterized by severe epigastric pain, nausea, and vomiting. Symptoms may progress to weakness, dizziness, confusion, slurred speech, unsteady gait, and loss of consciousness. BHT is highly lipid soluble. It may cross the blood brain barrier, causing psychotropic symptoms. BHT has been associated with development of cancer;”

    Butylated Hydroxytoluene (bht) · Natural Medicines adverse-effect record, reported in cancer.

    5 sources cited
    1. 10303. Shlian DM, Goldstone J. Toxicity of butylated hydroxytoluene. N Engl J Med 1986;314:648-9. DOI
    2. 10698. Grogan MW. Toxicity from BHT ingestion. West J Med 1986;145:245-6.
    3. 10699. Shlian DM, Goldstone J. More on BHT toxicity. West J Med 1986;145:699.
    4. 10292. Williams GM, Iatropoulos MJ, Whysner J. Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives. Food Chem Toxicol 1999;37:1027-38.. PubMed
    5. 10293. Botterweck AA, Verhagen H, Goldbohm RA, et al. Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study. Food Chem Toxicol 2000;38:599-605.. PubMed
  • Stomach upset / Dizziness / Vomiting / Nausea Additional detail

    Recorded for Butylated Hydroxytoluene (bht) in the same Natural Medicines adverse-effect record shown under Fainting / Confusion above.

Everything above comes from the Natural Medicines adverse-effect record for Butylated Hydroxytoluene (bht) — expand a row for the licensed statement it rests on. We haven’t matched Mobocertinib Succinate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Mobocertinib Succinate.

Special populations

Butylated Hydroxytoluene (bht) in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally as a food additive.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Mobocertinib Succinate

This page covers Butylated Hydroxytoluene (bht) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mobocertinib Succinate page lists 146 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 98 moderate · 40 minor.

From our pharmacist’s overview on the Mobocertinib Succinate page

“Mobocertinib (Exkivity) is a targeted therapy for a hard-to-treat lung cancer, which makes dosing precision matter and this list worth real caution. Most of the 146 supplements on file can shift the drug's blood level, because mobocertinib is cleared by CYP3A4, an enzyme many botanicals speed up or slow down.”

Reviewed by 2 · Jul 18, 2026

Open the Mobocertinib Succinate interaction page

How much people look this up

Where Butylated Hydroxytoluene (bht) and Mobocertinib Succinate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Butylated Hydroxytoluene (bht)
Steady interest

#1,248 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mobocertinib Succinate
Steady interest

#2,517 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Butylated Hydroxytoluene (bht) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Butylated Hydroxytoluene (bht) and Mobocertinib Succinate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Butylated Hydroxytoluene (bht)

What is Butylated Hydroxytoluene (bht)?

  • Antioxidant supplement
  • Antiviral (popular self-treatment for herpes-type viruses)
  • Food and supplement preservative
  • General 'anti-aging' use

Butylated hydroxytoluene (BHT) is a man-made antioxidant used mainly as a preservative in foods, cosmetics, and supplements. Some people take it as a supplement hoping for antiviral or anti-aging effects, but human evidence for these uses is very weak, and taking concentrated BHT carries real safety concerns. Talk with a pharmacist or doctor before using it as a supplement.

Synthetic compound (not from a plant) · Capsules, tablets, liquid drops, powder

An interaction check asks whether these two react with each other — it does not ask whether Butylated Hydroxytoluene (bht) is a good idea for someone in your situation. Here is what our Butylated Hydroxytoluene (bht) record says about it on its own.

Butylated Hydroxytoluene (bht): dosing

There is no established or proven safe supplement dose of BHT. It is not a standardized medical treatment, and doses found in supplements vary widely.If you choose to use a BHT product, follow the directions on the label and do not exceed them.

From our Butylated Hydroxytoluene (bht) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Butylated Hydroxytoluene (bht) monograph & all interactions
Medication

About Mobocertinib

What Is Mobocertinib Used For?

Brand name: Exkivity

  • Mobocertinib is used to treat a certain type of non-small cell lung cancer (NSCLC) that cannot be removed by surgery and has spread to other parts of the body either during or after treatment with platinum chemotherapy medications. Mobocertinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells and may help shrink tumors.

See full Mobocertinib drug information
Keep checking

Other Drugs & Butylated Hydroxytoluene (bht)

Browse every other medication we’ve checked against Butylated Hydroxytoluene (bht) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Butylated Hydroxytoluene (bht) References

The 6 references that drive our Butylated Hydroxytoluene (bht) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Williams GM, Iatropoulos MJ, Whysner J. Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives. Food Chem Toxicol 1999;37:1027-38.. PubMed
  2. Botterweck AA, Verhagen H, Goldbohm RA, et al. Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study. Food Chem Toxicol 2000;38:599-605.. PubMed
  3. Freeman DJ, Wenerstrom G, Spruance SL. Treatment of recurrent herpes simplex labialis with topical butylated hydroxytoluene. Clin Pharmacol Ther 1985;38:56-9.. PubMed
  4. Shlian DM, Goldstone J. Toxicity of butylated hydroxytoluene. N Engl J Med 1986;314:648-9. DOI
  5. Grogan MW. Toxicity from BHT ingestion. West J Med 1986;145:245-6.
  6. Shlian DM, Goldstone J. More on BHT toxicity. West J Med 1986;145:699.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Butylated Hydroxytoluene (bht) and Mobocertinib Succinate Together: Common Questions

Is it safe to take Butylated Hydroxytoluene (bht) with Mobocertinib Succinate?
We do not list a known interaction between Butylated Hydroxytoluene (bht) and Mobocertinib Succinate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Mobocertinib Succinate interact with any supplements?
Yes. Mobocertinib Succinate has documented interactions with 146 supplements in our database — Butylated Hydroxytoluene (bht) is not one of them. The Mobocertinib Succinate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Mobocertinib Succinate and Butylated Hydroxytoluene (bht)?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.