Cade + Ketoprofen
Ketoprofen brand names: Orudis, Oruvail Gel, Powergel, Oruvail Injection.
We found no known interaction between Cade and Ketoprofen in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ketoprofen states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Cade and Ketoprofen
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Ketoprofen and Cade in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Cade at all — not against Ketoprofen, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Cade safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Ketoprofen Products Have a Food Rule — Cade Should Not Break It
At least one FDA label for a product containing Ketoprofen says to take it with food. If you take Cade on an empty stomach out of habit, keep them separate — and take Ketoprofen with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ketoprofen products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Although food delays the absorption of both formulations (see CLINICAL PHARMACOLOGY ) in most of the clinical trials ketoprofen was taken with food or milk.
From the Dosage and Administration section of the FDA label we read for Ketoprofen — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Ketoprofen
This page covers Cade only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ketoprofen page lists 252 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Danshen (major) and Piracetam (major).
By severity: 7 major · 217 moderate · 28 minor.
From our pharmacist’s overview on the Ketoprofen page
“Bleeding is what worries me most with ketoprofen (Orudis, Oruvail Gel). As an NSAID, it already irritates the stomach lining and slows clotting, and 202 of the 252 supplements and herbs on this page can push that bleeding risk further.”
Reviewed by 2 · Jul 18, 2026
Where Cade and Ketoprofen Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#870 of 1,452 supplements looked up here in the last 7 days
#1,411 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cade reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cade and Ketoprofen records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Cade
What is Cade?
- Psoriasis and eczema
- Itchy or scaly scalp (dandruff)
- Minor skin irritation
- Antiseptic for the skin
- Hair and scalp care
Cade oil (juniper tar) is a dark, tar-like oil distilled from the wood of the prickly juniper and is used almost entirely on the skin and scalp for conditions like psoriasis, eczema, and dandruff. Good-quality human research is limited, and there are real safety concerns, so it should only be used on the skin, carefully and in small amounts. Talk with a pharmacist or doctor before using it, and never take it by mouth.
Juniperus oxycedrus · Cupressaceae · Wood and branches, used to make cade oil (juniper tar) · Cade oil (juniper tar), topical creams, ointments, shampoos, and soaps
An interaction check asks whether these two react with each other — it does not ask whether Cade is a good idea for someone in your situation. Here is what our Cade record says about it on its own.
Cade: dosing
There is no established standard dose for cade oil. It is most often found already mixed into shampoos, soaps, creams, or ointments at low concentrations rather than used as a pure oil.The best approach is to follow the directions on the product label and not apply more or more often than recommended.
From our Cade monograph — the full record covers uses, side effects and every documented interaction.
About Ketoprofen
What Is Ketoprofen Used For?
Brand names: Orudis, Oruvail Gel, Powergel, Oruvail Injection
Ketoprofen capsules (including the brand Orudis) are used to manage the signs and symptoms of rheumatoid arthritis and osteoarthritis, to treat pain, and to treat primary dysmenorrhea (painful menstrual periods).
Ketoprofen extended-release capsules are approved for rheumatoid arthritis and osteoarthritis only. Because of the way they slowly release the drug, ketoprofen extended-release capsules are not recommended for treating acute (sudden) pain.
Most-Reported Side Effects for Ketoprofen
From FAERS, the FDA’s public side-effect reporting system (13,040 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Cade
Browse every other medication we’ve checked against Cade — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Cade against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Valacyclovir ›
- Warfarin Sodium ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Cade list.
Cade References
The 5 references that drive our Cade monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Koruk, S. T., Ozyilkan, E., Kaya, P., Colak, D., Donderici, O., and Cesaretli, Y. Juniper tar poisoning. Clin.Toxicol.(Phila) 2005;43(1):47-49. PubMed
- Achour S, Abourazzak S, Mokhtari A, et al. Juniper tar (cade oil) poisoning in new born after a cutaneous application. BMJ Case Reports 2011 Oct 28;2011. PubMed
- Skalli S, Chebat A, Badrane N, Bencheikh RS. Side effects of cade oil in Morocco: an analysis of reports in the Moroccan herbal products database from 2004 to 2012. Food Chem Toxicol 2014;64:81-5. PubMed
- Rahmani H, Leonhardt S, Beladdale D, et al. Severe acute lung oedema after rectal enema with cade oil (abstract). European Association of Poisons Centres and Clinical Toxicologists XXIV International Congress, Strasbourg, 2004. Clin Toxicol 2004;42(4):487
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Ketoprofen Is Linked to Lower Levels of One Nutrient
Natural Medicines records Ketoprofen as a medicine that can lower these. This is not an interaction with Cade — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Ketoprofen nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Cade and Ketoprofen Together: Common Questions
Is it safe to take Cade with Ketoprofen?
Do Cade and Ketoprofen have any of the same side effects?
Should I take Cade and Ketoprofen at the same time of day?
Does Ketoprofen interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Ketoprofen and Cade?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.