Cade + Buspirone
Buspirone brand name: BuSpar.
We found no known interaction between Cade and Buspirone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Cade and Buspirone
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Buspirone and Cade in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Cade at all — not against Buspirone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Cade safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Questions About Cade or Buspirone
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Cade or Buspirone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- How Long Does Buspirone Stay in Your System? ›
- Questions About Combining Hydroxyzine And Buspirone ›
- Does Buspar (Buspirone) Work Right Away? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Buspirone
This page covers Cade only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Buspirone page lists 155 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), Lithium (major), St. John's Wort (major) and 5-htp (moderate).
By severity: 4 major · 108 moderate · 43 minor.
From our pharmacist’s overview on the Buspirone page
“I counsel genuine caution when supplements meet buspirone (BuSpar), the anxiety medication, because four of its 155 documented interactions are rated major. The bulk of the list, 121 ingredients, changes how your liver clears buspirone through the CYP3A4 enzyme, pushing its level up toward dizziness and drowsiness or down until the anx…”
Reviewed by 2 · Jul 18, 2026
Where Cade and Buspirone Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,212 of 1,452 supplements looked up here in the last 7 days
#54 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cade reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Cade and Buspirone records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Cade
What is Cade?
- Psoriasis and eczema
- Itchy or scaly scalp (dandruff)
- Minor skin irritation
- Antiseptic for the skin
- Hair and scalp care
Cade oil (juniper tar) is a dark, tar-like oil distilled from the wood of the prickly juniper and is used almost entirely on the skin and scalp for conditions like psoriasis, eczema, and dandruff. Good-quality human research is limited, and there are real safety concerns, so it should only be used on the skin, carefully and in small amounts. Talk with a pharmacist or doctor before using it, and never take it by mouth.
Juniperus oxycedrus · Cupressaceae · Wood and branches, used to make cade oil (juniper tar) · Cade oil (juniper tar), topical creams, ointments, shampoos, and soaps
An interaction check asks whether these two react with each other — it does not ask whether Cade is a good idea for someone in your situation. Here is what our Cade record says about it on its own.
Cade: dosing
There is no established standard dose for cade oil. It is most often found already mixed into shampoos, soaps, creams, or ointments at low concentrations rather than used as a pure oil.The best approach is to follow the directions on the product label and not apply more or more often than recommended.
From our Cade monograph — the full record covers uses, side effects and every documented interaction.
About Buspirone
What Is Buspirone Used For?
Brand name: BuSpar
Buspirone tablets and capsules are used to manage anxiety disorders or to relieve anxiety symptoms in the short term. Its effectiveness has been shown in clinical trials focused on Generalized Anxiety Disorder (GAD) — a condition marked by persistent, hard-to-control worry along with physical symptoms like muscle tension, restlessness, difficulty concentrating, and sleep problems.
Buspirone has also been shown to relieve anxiety in people who have mild depressive symptoms alongside their anxiety. Everyday stress and tension, on their own, generally do not require treatment with a medicine like buspirone.
Other Drugs & Cade
Browse every other medication we’ve checked against Cade — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Cade against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Ibuprofen ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Cade list.
Cade References
The 5 references that drive our Cade monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Koruk, S. T., Ozyilkan, E., Kaya, P., Colak, D., Donderici, O., and Cesaretli, Y. Juniper tar poisoning. Clin.Toxicol.(Phila) 2005;43(1):47-49. PubMed
- Achour S, Abourazzak S, Mokhtari A, et al. Juniper tar (cade oil) poisoning in new born after a cutaneous application. BMJ Case Reports 2011 Oct 28;2011. PubMed
- Skalli S, Chebat A, Badrane N, Bencheikh RS. Side effects of cade oil in Morocco: an analysis of reports in the Moroccan herbal products database from 2004 to 2012. Food Chem Toxicol 2014;64:81-5. PubMed
- Rahmani H, Leonhardt S, Beladdale D, et al. Severe acute lung oedema after rectal enema with cade oil (abstract). European Association of Poisons Centres and Clinical Toxicologists XXIV International Congress, Strasbourg, 2004. Clin Toxicol 2004;42(4):487
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Cade and Buspirone Together: Common Questions
Is it safe to take Cade with Buspirone?
Do Cade and Buspirone have any of the same side effects?
Does Buspirone interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Buspirone and Cade?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.