Drug & supplement interaction

Caffeic Acid + Colistin, Neomycin, Hydrocortisone

Colistin, Neomycin, Hydrocortisone brand name: Coly-Mycin S Otic.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Caffeic Acid and Colistin, Neomycin, Hydrocortisone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Caffeic Acid and Colistin, Neomycin, Hydrocortisone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Colistin, Neomycin, Hydrocortisone and Caffeic Acid in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Caffeic Acid safety at a glance

Caffeic Acid overall Use caution Generally well tolerated in food amounts, but concentrated supplement doses are not well studied in humans.
Pregnancy Avoid Not enough safety data on supplement doses; best to avoid beyond normal dietary intake.
Breastfeeding Avoid Safety of supplement doses is unknown, so avoid unless your doctor advises otherwise.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Colistin, Neomycin, Hydrocortisone and Caffeic Acid? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Keep it in perspective

Caffeic Acid Does Interact With Other Medications

Caffeic Acid has 177 moderate, 5 minor known drug interactions in our database — Colistin, Neomycin, Hydrocortisone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 177 Minor 5 No known interaction 2,648 (incl. Colistin, Neomycin, Hydrocortisone)
Taking anything else?

Check Another of Your Medications Against Caffeic Acid

Covers the 2,830 medications we’ve checked against Caffeic Acid. Pick one to open its full report.

One more smart check

Taking Caffeic Acid as Part of a Dietary Supplement Product? Check It for Interactions

We hold 20 real supplement products containing Caffeic Acid, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Caffeic Acid. Even though Caffeic Acid itself has no known interaction with Colistin, Neomycin, Hydrocortisone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Caffeic Acid and Colistin, Neomycin, Hydrocortisone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Caffeic Acid
Steady interest

#1,274 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Colistin, Neomycin, Hydrocortisone
Top half

#1,277 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Caffeic Acid reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Caffeic Acid and Colistin, Neomycin, Hydrocortisone records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Caffeic Acid

What is Caffeic Acid?

  • Antioxidant support
  • General anti-inflammatory use
  • Skin and sun protection (topical)
  • Immune support
  • Cancer-prevention interest (research stage)

Caffeic acid is a natural plant compound found in coffee, many fruits, vegetables, and herbs, and it is studied mainly for its antioxidant and anti-inflammatory properties. Most evidence comes from laboratory and animal research, so its benefits in people are not yet proven. If you want to take it as a supplement, talk with your pharmacist or doctor first.

Naturally occurring plant compound (found in coffee, fruits, and many herbs) · Capsules, tablets, powders, and as part of plant extracts (such as coffee or propolis)

An interaction check asks whether these two react with each other — it does not ask whether Caffeic Acid is a good idea for someone in your situation. Here is what our Caffeic Acid record says about it on its own.

Caffeic Acid: dosing

There is no established standard dose of caffeic acid as a supplement. Research studies have used different amounts, and a safe, effective dose for general use has not been confirmed.If you choose to use a product that contains caffeic acid, follow the directions on the label and do not exceed the recommended amount.

From our Caffeic Acid monograph — the full record covers uses, side effects and every documented interaction.

Read the full Caffeic Acid monograph & all interactions
Keep checking

Other Drugs & Caffeic Acid

Browse every other medication we’ve checked against Caffeic Acid — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
177Moderate
5Minor
2,647No known interaction
177 Moderate 5 Minor 2,647 No interaction
Moderate

177 interactions

Showing 60 of 177 moderate interactions — see all 177 on the Caffeic Acid page.

Minor

5 interactions

No interaction 2,647 drugs checked — show the list

We also checked Caffeic Acid against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Caffeic Acid list.

See the full Caffeic Acid interactions page
See every supplement checked against Colistin, Neomycin, Hydrocortisone, ranked by severity
Evidence & sources

Caffeic Acid References

The 2 references that drive our Caffeic Acid monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Uwai Y, Ozeki Y, Isaka T, et al. Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction. Drug Metab Pharmacokinet 2011;26:486-93. PubMed
  2. Wang LH, Hsu KY, Uang YS, et al. Caffeic acid improves the bioavailability of L-dopa in rabbit plasma. Phytother Res 2010;24:852-8.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Caffeic Acid and Colistin, Neomycin, Hydrocortisone Together: Common Questions

Is it safe to take Caffeic Acid with Colistin, Neomycin, Hydrocortisone?
We do not list a known interaction between Caffeic Acid and Colistin, Neomycin, Hydrocortisone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Caffeic Acid interact with any other medications?
Yes. Caffeic Acid has 182 documented drug interactions in our database — Colistin, Neomycin, Hydrocortisone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Caffeic Acid monograph Uses, safety profile, and every drug interaction in one place Colistin, Neomycin, Hydrocortisone supplement interactions Every supplement checked against Colistin, Neomycin, Hydrocortisone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Colistin, Neomycin, Hydrocortisone and Caffeic Acid?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.