Drug & supplement interaction

Caralluma + Ferric Citrate

Ferric Citrate brand name: Auryxia.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Caralluma and Ferric Citrate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ferric Citrate states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Caralluma and Ferric Citrate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ferric Citrate and Caralluma in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Caralluma at all — not against Ferric Citrate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Caralluma safety at a glance

Caralluma overall Use caution Generally tolerated short-term in studies, but long-term safety is not well established.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ferric Citrate and Caralluma? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Caralluma and Ferric Citrate May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Constipation Additional detail

    Caralluma

    “Orally, in clinical trials, side effects have included gastrointestinal upset, abdominal distention, flatulence, constipation, and gastritis. These side effects appeared to subside within the first two weeks of use and have also been reported in patients taking placebo.”

    Caralluma · Natural Medicines adverse-effect record, reported in constipation.

    Ferric Citrate

    Listed in the ADVERSE REACTIONS section of the FDA label for Ferric Citrate. Read the label on DailyMed ›

Reported for Caralluma but not commonly for Ferric Citrate: stomach upset, raised blood pressure and bloating or gas.

Effects for Ferric Citrate come from the ADVERSE REACTIONS section of its FDA label; effects for Caralluma come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Ferric Citrate Products Have a Food Rule — Caralluma Should Not Break It

At least one FDA label for a product containing Ferric Citrate says to take it with food. If you take Caralluma on an empty stomach out of habit, keep them separate — and take Ferric Citrate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ferric Citrate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.2 ) 2.1 Dosage for Hyperphosphatemia in Chronic Kidney Disease on Dialysis The recommended starting dose is 2 tablets, swallowed whole, 3 times per day with meals.

From the Dosage and Administration section of the FDA label we read for Ferric Citrate — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Ferric Citrate

This page covers Caralluma only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ferric Citrate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Ferric Citrate page

“Ferric citrate (Auryxia) does its work in the gut, binding dietary phosphate in kidney disease or supplying iron, and all 17 supplements on this list can interfere with how oral medicines get absorbed. That is worth real caution, starting with the single major-rated entry, activated charcoal, which adsorbs many drugs directly and can m…”

Reviewed by 2 · Jul 18, 2026

Open the Ferric Citrate interaction page

One more smart check

Taking Caralluma as Part of a Dietary Supplement Product? Check It for Interactions

We hold 151 real supplement products containing Caralluma, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Caralluma. Even though Caralluma itself has no known interaction with Ferric Citrate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Caralluma and Ferric Citrate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Caralluma
Top half

#671 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ferric Citrate
Steady interest

#2,380 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Caralluma reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Caralluma and Ferric Citrate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Caralluma

What is Caralluma?

  • Appetite suppression
  • Weight management
  • Reducing waist circumference
  • Boosting energy/endurance

Caralluma fimbriata is an edible succulent plant from India that is marketed mainly as an appetite suppressant and weight-loss aid. Some small studies suggest it may modestly reduce appetite or waist size, but the overall evidence is limited and not strong. Talk to your pharmacist or doctor before trying it, and avoid it during pregnancy and breastfeeding.

Caralluma fimbriata · Apocynaceae · Aerial parts (stems) and whole-plant extract · Capsules, tablets, powder, standardized extract

An interaction check asks whether these two react with each other — it does not ask whether Caralluma is a good idea for someone in your situation. Here is what our Caralluma record says about it on its own.

Caralluma: dosing

There is no official or well-established standard dose for Caralluma. Studies have used standardized extracts, but the amounts varied, and there is not enough consistent evidence to recommend a specific milligram dose.The best approach is to follow the directions on the product label and not exceed the recommended amount. Because supplement strengths differ, it is a good idea to review the specific product with your pharmacist or doctor before using it.

From our Caralluma monograph — the full record covers uses, side effects and every documented interaction.

Read the full Caralluma monograph & all interactions
Medication

About Ferric Citrate

What Is Ferric Citrate Used For?

Brand name: Auryxia

Ferric citrate tablets — sold as Auryxia and under the generic name Ferric Citrate — are approved for two related uses in adults with chronic kidney disease (CKD).

For patients on dialysis, they work as a phosphate binder to control high phosphorus (hyperphosphatemia) levels in the blood. For patients with CKD who are not on dialysis, they serve as an iron replacement to treat iron deficiency anemia.

Most-Reported Side Effects for Ferric Citrate

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 307 reports
Serum ferritin increased 228 reports
Transferrin saturation increased 169 reports
Faeces discoloured 118 reports
Constipation 83 reports
See full Ferric Citrate drug information
Keep checking

Other Drugs & Caralluma

Browse every other medication we’ve checked against Caralluma — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Caralluma against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Caralluma list.

See the full Caralluma interactions page
See every supplement checked against Ferric Citrate, ranked by severity
Evidence & sources

Caralluma References

The 1 references that drive our Caralluma monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Arora E, Khajuria V, Tandon VR, et al. To evaluate efficacy and safety of Caralluma fimbriata in overweight and obese patients: a randomized, single blinded, placebo control trial. Perspect Clin Res 2015;6(1):39-44. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Caralluma and Ferric Citrate Together: Common Questions

Is it safe to take Caralluma with Ferric Citrate?
We do not list a known interaction between Caralluma and Ferric Citrate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Caralluma and Ferric Citrate have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Caralluma and Ferric Citrate at the same time of day?
At least one FDA label for a product containing Ferric Citrate says to take it with food. If you take Caralluma on an empty stomach out of habit, keep them separate and take Ferric Citrate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Ferric Citrate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Ferric Citrate interact with any supplements?
Yes. Ferric Citrate has documented interactions with 17 supplements in our database — Caralluma is not one of them. The Ferric Citrate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Caralluma monograph Uses, safety profile, and every drug interaction in one place Ferric Citrate drug information The full plain-English guide to this medication Ferric Citrate supplement interactions Every supplement checked against Ferric Citrate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ferric Citrate and Caralluma?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.