Drug & supplement interaction

Cardamom + Gabapentin

Gabapentin brand names: Neurontin, Gralise.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Cardamom and Gabapentin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Cardamom and Gabapentin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Gabapentin and Cardamom in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Cardamom at all — not against Gabapentin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cardamom safety at a glance

Cardamom overall Generally safe Amounts used in food are generally well tolerated by most people.
Pregnancy Use caution Food amounts are likely fine, but avoid concentrated supplement or essential oil doses without medical advice.
Breastfeeding Likely Safe When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of cardamom when used in medicinal am... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Gabapentin and Cardamom? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Cardamom Itself Has Been Linked To

This is not an interaction — nothing below involves Gabapentin. It is the side-effect record for Cardamom on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Cardamom, this list is the first place to look.

  • A skin rash Additional detail

    “Orally, mild skin inflammation due to cardamom has been reported in one participant of a clinical trial. Topically, a case report describes chronic hand dermatitis in a confectioner frequently exposed to cardamom. Skin patch tests were positive for cardamom, and for terpenoids present in the seeds.”

    Cardamom · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 101887. Aghasi M, Koohdani F, Qorbani M, et al. Beneficial effects of green cardamom on serum SIRT1, glycemic indices and triglyceride levels in patients with type 2 diabetes mellitus: a randomized double-blind placebo controlled clinical trial. J Sci Food Agri PubMed
    2. 39875. Mobacken, H. and Fregert, S. Allergic contact dermatitis from cardamom. Contact Dermatitis 1975;1(3):175-176. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Cardamom — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Gabapentin’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Gabapentin column appears here.

Special populations

Cardamom in Pregnancy & Breastfeeding

Lactation Likely Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of cardamom when used in medicinal amounts. Avoid using amounts greater than those used in food.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Gabapentin Is Prescribed For, and What Cardamom Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Gabapentin is a prescription medicine with approved uses on its FDA label. Cardamom is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Gabapentin is prescribed for: Gabapentin (brands include Neurontin, Relgaabi, Gabarone, Gralise, and Horizant) is primarily used to manage postherpetic neuralgia (PHN) — the nerve pain that lingers after a shingles outbreak — in adults. Neurontin, Relgaabi, Gabarone, and gabapentin capsules, tablets, and oral solution are also used as add-on therapy for partial onset seizures (a type of epilepsy) in adults and children aged 3 and older. Horizant (gabapentin enacarbil extended-release tablet) has two specific approvals: treatment of moderate-to-severe primary restless legs syndrome (RLS) in adults, and management of postherpetic neuralgia in adults. Horizant is not recommended for people who need to sleep during the day and stay awake at night.

Read the rest of what Gabapentin is prescribed for

Gralise is approved only for postherpetic neuralgia and cannot be substituted for other gabapentin products due to its different release profile.

Cardamom has been studied for:

  • Epilepsy studied, not established Cardamom has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Cardamom for epilepsy

    Although there has been interest in using oral cardamom essential oil for epilepsy, there is insufficient reliable information about the clinical effects of cardamom for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Gabapentin on your own; if you are taking Cardamom for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Cardamom or Gabapentin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Cardamom or Gabapentin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Gabapentin

This page covers Cardamom only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Gabapentin page lists 106 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 82 moderate · 17 minor.

From our pharmacist’s overview on the Gabapentin page

“Gabapentin (Neurontin, Gralise) calms overactive nerves, which means it already slows your nervous system down, and that is exactly what 78 of the 106 supplements on this list also do. So the dominant risk here is sedation stacked on sedation, extra drowsiness at best and dangerously slowed breathing at worst, and with seven entries ra…”

Reviewed by 2 · Jul 18, 2026

Open the Gabapentin interaction page

One more smart check

Taking Cardamom as Part of a Dietary Supplement Product? Check It for Interactions

We hold 844 real supplement products containing Cardamom, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cardamom. Even though Cardamom itself has no known interaction with Gabapentin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cardamom and Gabapentin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cardamom
Top 25%

#221 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Gabapentin
Top 5%

#41 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cardamom reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Cardamom and Gabapentin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cardamom

What is Cardamom?

  • Digestive upset and bloating
  • Bad breath
  • Nausea
  • Flavoring in food and drinks
  • General antioxidant support

Cardamom is a popular cooking spice that has long been used in traditional medicine for digestion and fresh breath. As a food, it is generally safe for most people, but high-dose supplements have not been well studied, so the health benefits remain mostly unproven. If you want to use concentrated cardamom products, check with your pharmacist or doctor first.

Elettaria cardamomum · Zingiberaceae · Seeds (from the dried fruit pods) and essential oil · Whole pods, ground spice, tea, capsules, extracts, and essential oil

An interaction check asks whether these two react with each other — it does not ask whether Cardamom is a good idea for someone in your situation. Here is what our Cardamom record says about it on its own.

Cardamom: dosing

There is no official or standardized medicinal dose for cardamom. As a spice, people use it freely in cooking, which is considered safe.For supplements, capsules, or extracts, the right amount varies by product, and a proven effective dose has not been established. The safest approach is to follow the directions on the product label and not exceed them.

From our Cardamom monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cardamom monograph & all interactions
Medication

About Gabapentin

What Is Gabapentin Used For?

Brand names: Neurontin, Gralise

Gabapentin (brands include Neurontin, Relgaabi, Gabarone, Gralise, and Horizant) is primarily used to manage postherpetic neuralgia (PHN) — the nerve pain that lingers after a shingles outbreak — in adults. Neurontin, Relgaabi, Gabarone, and gabapentin capsules, tablets, and oral solution are also used as add-on therapy for partial onset seizures (a type of epilepsy) in adults and children aged 3 and older.

Horizant (gabapentin enacarbil extended-release tablet) has two specific approvals: treatment of moderate-to-severe primary restless legs syndrome (RLS) in adults, and management of postherpetic neuralgia in adults. Horizant is not recommended for people who need to sleep during the day and stay awake at night. Gralise is approved only for postherpetic neuralgia and cannot be substituted for other gabapentin products due to its different release profile.

Most-Reported Side Effects for Gabapentin

From FAERS, the FDA’s public side-effect reporting system (361,481 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 24,972 reports
Nausea 22,728 reports
Diarrhea 18,114 reports
Headache 17,897 reports
Dizziness 16,238 reports
See full Gabapentin drug information
Keep checking

Other Drugs & Cardamom

Browse every other medication we’ve checked against Cardamom — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Cardamom against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Cardamom list.

See the full Cardamom interactions page
See every supplement checked against Gabapentin, ranked by severity
Evidence & sources

Cardamom References

The 2 references that drive our Cardamom monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Mobacken, H. and Fregert, S. Allergic contact dermatitis from cardamom. Contact Dermatitis 1975;1(3):175-176. PubMed
  2. Aghasi M, Koohdani F, Qorbani M, et al. Beneficial effects of green cardamom on serum SIRT1, glycemic indices and triglyceride levels in patients with type 2 diabetes mellitus: a randomized double-blind placebo controlled clinical trial. J Sci Food Agri PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cardamom and Gabapentin Together: Common Questions

Is it safe to take Cardamom with Gabapentin?
We do not list a known interaction between Cardamom and Gabapentin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Cardamom and Gabapentin used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Cardamom in each. That is a conversation for your prescriber, especially if Gabapentin is being adjusted to a target.
Does Gabapentin interact with any supplements?
Yes. Gabapentin has documented interactions with 106 supplements in our database — Cardamom is not one of them. The Gabapentin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Cardamom monograph Uses, safety profile, and every drug interaction in one place Gabapentin drug information The full plain-English guide to this medication Gabapentin supplement interactions Every supplement checked against Gabapentin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Gabapentin and Cardamom?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.