Drug & supplement interaction

Cassia Nomame + Darunavir, Cobicistat

Darunavir, Cobicistat brand name: Prezcobix.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Cassia Nomame and Darunavir, Cobicistat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Darunavir, Cobicistat states a food rule worth keeping to.

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Interaction report

Cassia Nomame and Darunavir, Cobicistat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Darunavir, Cobicistat and Cassia Nomame in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Cassia Nomame at all — not against Darunavir, Cobicistat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cassia Nomame safety at a glance

Cassia Nomame overall Use caution Limited human safety data, so use cautiously and under guidance.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid No reliable safety data; best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Darunavir, Cobicistat and Cassia Nomame? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Darunavir, Cobicistat’s Own FDA Label Lists

This is not an interaction — none of it involves Cassia Nomame. These are the most notable effects listed in the ADVERSE REACTIONS section of Darunavir, Cobicistat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on
  • Liver problems Worth acting on
  • Stomach pain
  • Diarrhea
  • A skin rash
  • Vomiting
  • Headache
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Darunavir, Cobicistat. Read the label on DailyMed › Cassia Nomame’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cassia Nomame side to compare — that is a limit of the record, not a statement that Cassia Nomame has no side effects.

How to take them

Some Darunavir, Cobicistat Products Have a Food Rule — Cassia Nomame Should Not Break It

At least one FDA label for a product containing Darunavir, Cobicistat says to take it with food. If you take Cassia Nomame on an empty stomach out of habit, keep them separate — and take Darunavir, Cobicistat with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Darunavir, Cobicistat products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION Recommended dosage: Adults and pediatric patients weighing at least 40 kg: One 800 mg/150 mg tablet taken once daily with food.

From the Dosage and Administration section of the FDA label we read for Darunavir, Cobicistat — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Darunavir, Cobicistat

This page covers Cassia Nomame only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Darunavir, Cobicistat page lists 145 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 102 moderate · 40 minor.

From our pharmacist’s overview on the Darunavir, Cobicistat page

“Prezcobix (darunavir with cobicistat) treats HIV, and it only works if it holds a steady blood level, so this list of 145 supplements deserves real care. Three carry a major rating and matter most: St.”

Reviewed by 2 · Jul 18, 2026

Open the Darunavir, Cobicistat interaction page

One more smart check

Taking Cassia Nomame as Part of a Dietary Supplement Product? Check It for Interactions

We hold 49 real supplement products containing Cassia Nomame, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cassia Nomame. Even though Cassia Nomame itself has no known interaction with Darunavir, Cobicistat, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cassia Nomame and Darunavir, Cobicistat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cassia Nomame
Steady interest

#1,097 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Darunavir, Cobicistat
Top half

#825 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Cassia Nomame is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cassia Nomame reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Cassia Nomame and Darunavir, Cobicistat records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cassia Nomame

What is Cassia Nomame?

  • Weight management
  • Reducing dietary fat absorption
  • Mild fluid retention (diuretic use)
  • Digestive support
  • General 'detox' or slimming blends

Cassia nomame is a legume plant traditionally used in parts of Asia and now marketed mainly in weight-loss supplements for its supposed ability to block fat absorption. Human evidence is very limited and weak, so it should not be relied on for weight loss. If you want to try it, talk with your pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Chamaecrista nomame · Fabaceae · Whole plant (aerial parts), often used as a tea or extract · Capsules, tablets, tea, and standardized extracts (sometimes in weight-loss blends)

An interaction check asks whether these two react with each other — it does not ask whether Cassia Nomame is a good idea for someone in your situation. Here is what our Cassia Nomame record says about it on its own.

Cassia Nomame: dosing

There is no well-established or standardized dose for Cassia nomame. It is most often found in combination products, so the amount varies a lot from one brand to another.If you choose to use it, follow the directions on the product label and do not take more than recommended.

From our Cassia Nomame monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cassia Nomame monograph & all interactions
Medication

About Darunavir and Cobicistat

What Is Darunavir and Cobicistat Used For?

Brand name: Prezcobix

Prezcobix and Prezcobix Ped are used to treat HIV-1 (human immunodeficiency virus type 1) infection. They are always used together with other antiretroviral (anti-HIV) medicines — never alone. Both products are approved for people who are new to HIV treatment (treatment-naïve) and for those who have taken HIV medicines before (treatment-experienced), as long as certain darunavir resistance mutations are not present.

Prezcobix tablets are approved for adults and pediatric patients weighing at least 40 kg. Prezcobix Ped tablets for oral suspension extend coverage to pediatric patients 3 years of age and older weighing at least 15 kg.

See full Darunavir and Cobicistat drug information
Keep checking

Other Drugs & Cassia Nomame

Browse every other medication we’ve checked against Cassia Nomame — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Cassia Nomame References

The 3 sources that drive our Cassia Nomame monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Cassia Nomame is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements for Weight Loss — NIH Office of Dietary Supplements Source
  2. Herbs at a Glance — NIH NCCIH Source
  3. Dietary Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cassia Nomame and Darunavir, Cobicistat Together: Common Questions

Is it safe to take Cassia Nomame with Darunavir, Cobicistat?
We do not list a known interaction between Cassia Nomame and Darunavir, Cobicistat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Cassia Nomame and Darunavir, Cobicistat at the same time of day?
At least one FDA label for a product containing Darunavir, Cobicistat says to take it with food. If you take Cassia Nomame on an empty stomach out of habit, keep them separate and take Darunavir, Cobicistat with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Darunavir, Cobicistat products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Darunavir, Cobicistat interact with any supplements?
Yes. Darunavir, Cobicistat has documented interactions with 145 supplements in our database — Cassia Nomame is not one of them. The Darunavir, Cobicistat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Darunavir, Cobicistat and Cassia Nomame?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.