Herb & supplement monograph

Cassia Nomame Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Cassia Nomame

0 medications have a known interaction with Cassia Nomame, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Cassia Nomame. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Cassia Nomame combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Cassia Nomame: Uses, Safety & Side Effects

The bottom line

Cassia nomame is a legume plant traditionally used in parts of Asia and now marketed mainly in weight-loss supplements for its supposed ability to block fat absorption. Human evidence is very limited and weak, so it should not be relied on for weight loss. If you want to try it, talk with your pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Scientific name
Chamaecrista nomame
Family
Fabaceae
Part used
Whole plant (aerial parts), often used as a tea or extract
Common forms
Capsules, tablets, tea, and standardized extracts (sometimes in weight-loss blends)
People commonly use it for
  • Weight management
  • Reducing dietary fat absorption
  • Mild fluid retention (diuretic use)
  • Digestive support
  • General 'detox' or slimming blends

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Limited human safety data, so use cautiously and under guidance.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Cassia nomame is a small flowering plant in the legume (bean) family. It is sometimes called by its scientific name, Chamaecrista nomame, and it grows in parts of East Asia, including Japan, Korea, and China. It has a long history of traditional use, where the plant was brewed into teas and used as a folk remedy.

Today, Cassia nomame is best known as an ingredient in dietary supplements marketed for weight loss. It is often combined with other herbs in 'fat-blocker' or 'slimming' products and sold as capsules, tablets, or teas.

Uses & effectiveness

People most often take Cassia nomame hoping it will help with weight loss by reducing how much fat the body absorbs from food. It has also been used traditionally as a mild diuretic (a 'water pill') and for digestive complaints.

The scientific evidence behind these uses is very limited. Most of the research comes from laboratory or test-tube studies that look at how the plant's compounds affect fat-digesting enzymes. There is little good-quality human research to show that Cassia nomame leads to meaningful or lasting weight loss. Because of this, it should be considered unproven for any health condition.

How it works

Cassia nomame contains natural plant compounds, including flavonoids, that have been studied in the lab for their effect on an enzyme called lipase. Lipase helps your body break down and absorb fat from food. The idea is that if this enzyme is partly blocked, some fat passes through the body undigested instead of being absorbed.

It is important to know that most of this evidence comes from laboratory and animal studies, not from strong human trials. So while the proposed mechanism sounds reasonable, we cannot say with confidence that it works this way in people who take the supplement.

Safety & precautions

There is not much reliable safety information about Cassia nomame, especially for long-term use. Because it may act like a mild diuretic, people who are dehydrated, take water pills, or have kidney problems should be especially careful.

People with existing health conditions, those who are older, and anyone taking prescription medicines should check with a pharmacist or doctor before using it. Pregnant and breastfeeding women should avoid Cassia nomame because there is no good safety data for these groups. Always buy supplements from reputable brands, since herbal products are not tightly regulated and quality can vary.

Side effects

Reported side effects are not well documented, but supplements that affect fat absorption or act as diuretics can cause digestive upset, such as loose stools, oily stools, gas, or stomach cramps. Diuretic effects could lead to increased urination and, in some cases, dehydration or electrolyte changes.

Stop using the product and seek medical care if you notice an allergic reaction (such as rash, itching, swelling, or trouble breathing) or any other unexpected, severe symptoms.

Dosing

There is no well-established or standardized dose for Cassia nomame. It is most often found in combination products, so the amount varies a lot from one brand to another.

If you choose to use it, follow the directions on the product label and do not take more than recommended. Because reliable dosing guidance is lacking, it is a good idea to talk with your pharmacist or doctor before starting, especially if you take other medicines or have health conditions.

Pregnancy & Breastfeeding

Cassia Nomame & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Cassia Nomame & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 3 sources that drive our Cassia Nomame monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Dietary Supplements for Weight Loss — NIH Office of Dietary Supplements Source
  2. Herbs at a Glance — NIH NCCIH Source
  3. Dietary Supplements — MedlinePlus Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Product directory

Supplement products with Cassia Nomame

49 products in our database contain Cassia Nomame. Open any to see its full ingredient list and every drug interaction we check.

Carb Shield by Top Trainer Capsule 120 Capsule(s) View ingredients & interactions Cassia Nomame by Genesis Today Capsule 60 Vegetarian Capsule(s) View ingredients & interactions Cheaters Relief by BSN Capsule 120 Capsule(s) View ingredients & interactions GH MALE by NaturesPlus Capsule 60 Capsule(s) View ingredients & interactions GHT Male by NaturesPlus Capsule 90 Vegetarian Capsule(s) View ingredients & interactions Healthy Weight Formula by Vitabase Tablet Or Pill 90 Tablet(s) View ingredients & interactions ISO Lean 1 by ANS Capsule 60 Capsule(s) View ingredients & interactions Iso Lean 1 Stimfree by Advanced Nutrition Systems Capsule 60 Capsule(s) View ingredients & interactions Keto-Max by NDS Capsule 90 Capsule(s) View ingredients & interactions Keto-XT by BPI Capsule 90 Capsule(s) View ingredients & interactions Lean EFX by Formutech Nutrition Capsule 45 Capsule(s) View ingredients & interactions Lipodrene by Hi-Tech Pharmaceuticals Tablet Or Pill 90 ct View ingredients & interactions Lipodrene by HTP Hi-Tech Pharmaceuticals Tablet Or Pill 90 Tablet(s) View ingredients & interactions Lipodrene Hardcore by Hi-Tech Pharmaceuticals Tablet Or Pill 90 ct View ingredients & interactions Lipodrene Hardcore by Hi-Tech Pharmaceuticals Tablet Or Pill 90 ct View ingredients & interactions Lipodrene with 25 mg Ephedra Extract by Hi-Tech Pharmaceuticals Tablet Or Pill 100 Tablet(s) View ingredients & interactions Millennium CFX by Thermo-Lift Other (e.g. Tea Bag) 60 Caplet(s) View ingredients & interactions Racing Fruit Punch by Image Sports Powder 3.17 oz. · 90 Gram(s) View ingredients & interactions Racing Fruit Punch by Image Sports Powder 3.17 oz. · 90 g View ingredients & interactions Racing Raspberry Lemonade by Image Sports Powder 3.17 oz. · 90 g View ingredients & interactions Racing Watermelon by Image Sports Powder 3.17 oz. · 90 g View ingredients & interactions Stacker 2 by Stacker 2 Capsule 100 Capsule(s) View ingredients & interactions Stim 10 by EXT Capsule 56 Capsule(s) View ingredients & interactions Tone Clinical by Complete Nutrition Softgel Capsule 180 Softgel(s) View ingredients & interactions
Pharmacist Counseling Corner

Cassia Nomame: Common Questions

Does Cassia Nomame interact with prescription medications?
We do not currently list any known drug interactions for Cassia Nomame. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Cassia Nomame interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Cassia Nomame with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Cassia Nomame interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Cassia Nomame used for?
It is mainly used in dietary supplements marketed for weight loss, based on the idea that it blocks fat absorption. It has also been used traditionally as a mild diuretic and for digestion, but strong evidence is lacking.
Does Cassia Nomame actually help with weight loss?
There is no strong human evidence that it leads to meaningful weight loss. Most research is from lab studies, so it should not be relied on as a weight-loss treatment.
Is Cassia Nomame safe to take?
Safety data is limited. It may cause digestive upset and could act as a mild diuretic, so it's best to check with a pharmacist or doctor before using it, especially if you have health conditions.
Can I take Cassia Nomame while pregnant or breastfeeding?
No. Because there is no reliable safety information, it should be avoided during pregnancy and breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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