Drug & supplement interaction

Cassia Nomame + Misoprostol

Misoprostol brand name: Cytotec.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Cassia Nomame and Misoprostol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Misoprostol states a food rule worth keeping to.

Know someone taking this? Share
Interaction report

Cassia Nomame and Misoprostol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Misoprostol and Cassia Nomame in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Cassia Nomame at all — not against Misoprostol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cassia Nomame safety at a glance

Cassia Nomame overall Use caution Limited human safety data, so use cautiously and under guidance.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid No reliable safety data; best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Misoprostol and Cassia Nomame? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Misoprostol’s Own FDA Label Lists

This is not an interaction — none of it involves Cassia Nomame. These are the most notable effects listed in the ADVERSE REACTIONS section of Misoprostol’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Hearing loss Worth acting on
  • Pain or burning when passing urine Worth acting on
  • Dehydration Worth acting on
  • Trouble swallowing Worth acting on
  • Bleeding in the gut Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Fainting Worth acting on
  • Wheezing Worth acting on
  • An irregular heartbeat Worth acting on

Showing the 10 most notable of 51 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Misoprostol. Read the label on DailyMed › Where a percentage is shown, it is the share of 16,478 voluntary FDA FAERS reports for Misoprostol that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Cassia Nomame’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cassia Nomame side to compare — that is a limit of the record, not a statement that Cassia Nomame has no side effects.

How to take them

Some Misoprostol Products Have a Food Rule — Cassia Nomame Should Not Break It

At least one FDA label for a product containing Misoprostol says to take it with food. If you take Cassia Nomame on an empty stomach out of habit, keep them separate — and take Misoprostol with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Misoprostol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

DOSAGE AND ADMINISTRATION The recommended adult oral dose of Cytotec for reducing the risk of NSAID-induced gastric ulcers is 200 mcg four times daily with food.

From the Dosage and Administration section of the FDA label we read for Misoprostol — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Misoprostol

This page covers Cassia Nomame only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Misoprostol page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Misoprostol page

“Misoprostol (Cytotec) is taken by mouth to protect the stomach lining from ulcers caused by NSAID pain relievers, and all 17 of its recorded supplement interactions come down to the same problem, something in the gut keeping the pill from being absorbed properly. That deserves genuine wariness, because misoprostol that never reaches th…”

Reviewed by 2 · Jul 18, 2026

Open the Misoprostol interaction page

One more smart check

Taking Cassia Nomame as Part of a Dietary Supplement Product? Check It for Interactions

We hold 49 real supplement products containing Cassia Nomame, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cassia Nomame. Even though Cassia Nomame itself has no known interaction with Misoprostol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cassia Nomame and Misoprostol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cassia Nomame
Steady interest

#1,225 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Misoprostol
Steady interest

#1,590 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Cassia Nomame is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cassia Nomame reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cassia Nomame and Misoprostol records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cassia Nomame

What is Cassia Nomame?

  • Weight management
  • Reducing dietary fat absorption
  • Mild fluid retention (diuretic use)
  • Digestive support
  • General 'detox' or slimming blends

Cassia nomame is a legume plant traditionally used in parts of Asia and now marketed mainly in weight-loss supplements for its supposed ability to block fat absorption. Human evidence is very limited and weak, so it should not be relied on for weight loss. If you want to try it, talk with your pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Chamaecrista nomame · Fabaceae · Whole plant (aerial parts), often used as a tea or extract · Capsules, tablets, tea, and standardized extracts (sometimes in weight-loss blends)

An interaction check asks whether these two react with each other — it does not ask whether Cassia Nomame is a good idea for someone in your situation. Here is what our Cassia Nomame record says about it on its own.

Cassia Nomame: dosing

There is no well-established or standardized dose for Cassia nomame. It is most often found in combination products, so the amount varies a lot from one brand to another.If you choose to use it, follow the directions on the product label and do not take more than recommended.

From our Cassia Nomame monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cassia Nomame monograph & all interactions
Medication

About Misoprostol

What Is Misoprostol Used For?

Brand name: Cytotec

Cytotec (misoprostol) tablets and misoprostol tablets are approved to reduce the risk of gastric ulcers (stomach ulcers) in patients who take NSAIDs — nonsteroidal anti-inflammatory drugs such as aspirin, ibuprofen, or diclofenac — and who are at high risk of ulcer complications. High-risk patients include older adults, people with serious ongoing illnesses, and those with a history of stomach ulcers.

It is important to note that misoprostol has not been shown to reduce the risk of duodenal ulcers (ulcers in the first part of the small intestine) in people taking NSAIDs. It also does not relieve the stomach pain or discomfort that NSAIDs can cause.

Most-Reported Side Effects for Misoprostol

From FAERS, the FDA’s public side-effect reporting system (16,478 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hemorrhage 1,322 reports
Abortion incomplete 1,159 reports
Nausea 1,031 reports
Arthralgia 977 reports
Rheumatoid arthritis 805 reports
See full Misoprostol drug information
Keep checking

Other Drugs & Cassia Nomame

Browse every other medication we’ve checked against Cassia Nomame — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Cassia Nomame References

The 3 sources that drive our Cassia Nomame monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Cassia Nomame is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements for Weight Loss — NIH Office of Dietary Supplements Source
  2. Herbs at a Glance — NIH NCCIH Source
  3. Dietary Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cassia Nomame and Misoprostol Together: Common Questions

Is it safe to take Cassia Nomame with Misoprostol?
We do not list a known interaction between Cassia Nomame and Misoprostol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Cassia Nomame and Misoprostol at the same time of day?
At least one FDA label for a product containing Misoprostol says to take it with food. If you take Cassia Nomame on an empty stomach out of habit, keep them separate and take Misoprostol with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Misoprostol products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Misoprostol interact with any supplements?
Yes. Misoprostol has documented interactions with 17 supplements in our database — Cassia Nomame is not one of them. The Misoprostol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Misoprostol and Cassia Nomame?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.