Catechu - Cyclosporine Interaction
Herbal: Catechu
Also Known As: Black catechu, Acacia catechu: Acacia à Cachou, Acacia Catechu Heartwood Extract, Black Catechu, Black Cutch, Cachou, Cachou de Pegu, Cachou Noir, Acacia Cashoo, Cashou, Catechu Nigrum, Catecu, Cutch, Cutchtree, Dark Catechu, Er Cha, Khadira, Khair, Kher, Khoyer
Drug: Cyclosporine
Brand names:
Neoral, Gengraf, Sandimmune, Ciclosporine, Cequa, Verkazia
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 22, 2025
Interaction Details
Cyclosporine is classified as belonging to the following category: Immunosuppressants
Theoretically, catechu might interfere with immunosuppressant therapy.
Animal and in vitro studies suggest that catechu has immunomodulating effects.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Sunil MA, Sunitha VS, Ashitha A, et al. Catechin rich butanol fraction extracted from Acacia catechu L. (a thirst quencher) exhibits immunostimulatory potential. J Food Drug Anal. 2019;27(1):195-207.
Catechu Overview
Catechu, also known as catechu gum or catechu extract, is a natural substance that is extracted from the Acacia catechu tree, which is native to parts of Asia. It is a brown, sticky substance that is used in traditional medicine and as a natural dye.
Catechu has a number of potential health benefits and has been used in traditional medicine for centuries. It is believed to have astringent, anti-inflammatory, and antioxidant properties, and it is often used to treat a range of health conditions, including gastrointestinal disorders, mouth sores, and skin wounds.
Cyclosporine Overview
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Cyclosporine and cyclosporine (modified) are used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants. Cyclosporine (modified) is also used alone or with methotrexate (Rheumatrex) to treat the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints) in patients whose symptoms were not relieved by methotrexate alone. Cyclosporine (modified) is also used to treat psoriasis (a skin disease in which red, scaly patches form on some areas of the body) in certain patients who have not been helped by other treatments. Cyclosporine and cyclosporine (modified) are in a class of medications called immunosuppressants. They work by decreasing the activity of the immune system.
Catechu - More Interactions
Catechu interacts with 462 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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