Citronella Oil + Alpelisib
Alpelisib brand name: Piqray.
We found no known interaction between Citronella Oil and Alpelisib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Alpelisib states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Citronella Oil and Alpelisib
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Alpelisib and Citronella Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Citronella Oil at all — not against Alpelisib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Citronella Oil safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Alpelisib Products Have a Food Rule — Citronella Oil Should Not Break It
At least one FDA label for a product containing Alpelisib says to take it with food. If you take Citronella Oil on an empty stomach out of habit, keep them separate — and take Alpelisib with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Alpelisib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
2 DOSAGE AND ADMINISTRATION Recommended Dose: Pediatric patients (2 to less than 18 years of age): 50 mg taken orally once daily with food.
From the Dosage and Administration section of the FDA label we read for Alpelisib — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Alpelisib
This page covers Citronella Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Alpelisib page lists 139 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 96 moderate · 40 minor.
From our pharmacist’s overview on the Alpelisib page
“Alpelisib (Piqray) treats PIK3CA-mutated breast cancer, and a drug doing that job leaves little room for supplements that shift its blood level. Yet that is what most of this list does: 121 of the 139 ingredients on file can raise or lower alpelisib through CYP3A4, the liver enzyme that clears it.”
Reviewed by 2 · Jul 18, 2026
Where Citronella Oil and Alpelisib Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#837 of 1,452 supplements looked up here in the last 7 days
#1,207 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Citronella Oil reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Citronella Oil and Alpelisib records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Citronella Oil
What is Citronella Oil?
- Insect and mosquito repellent
- Aromatherapy and relaxation
- Topical antimicrobial
- Fragrance in soaps and household products
- Skin and hair care products
Citronella oil is an essential oil made from a tropical grass and is best known as a natural insect repellent. Some evidence supports short-term mosquito protection, but it usually does not last as long as conventional repellents like DEET. It is meant for skin or air use, not for swallowing, and can irritate sensitive skin.
Cymbopogon nardus · Poaceae · Leaves and grass (steam-distilled essential oil) · Essential oil, sprays, lotions, candles, diffuser oil
An interaction check asks whether these two react with each other — it does not ask whether Citronella Oil is a good idea for someone in your situation. Here is what our Citronella Oil record says about it on its own.
Citronella Oil: dosing
There is no official standardized dose for citronella oil. For skin use, it is usually diluted with a carrier oil (such as coconut or almond oil) in commercial repellent products. For aromatherapy, a few drops are added to a diffuser or warm water.Because product strengths vary widely, the best approach is to follow the directions on the label and reapply repellent products as instructed.
From our Citronella Oil monograph — the full record covers uses, side effects and every documented interaction.
About Alpelisib
What Is Alpelisib Used For?
Brand name: Piqray
Piqray is used with fulvestrant to treat adults with advanced or metastatic breast cancer that is hormone receptor (HR)-positive, HER2-negative and PIK3CA-mutated. It is for use after the cancer has progressed on or after an endocrine-based (hormone-blocking) treatment. An FDA-approved test must detect the mutation.
Vijoice is used for adults and children 2 years and older with severe PROS who need systemic (whole-body) therapy. This use has accelerated approval, which is based on response rate and duration of response. Continued approval may depend on confirmatory trials.
Most-Reported Side Effects for Alpelisib
From FAERS, the FDA’s public side-effect reporting system (8,666 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Citronella Oil
Browse every other medication we’ve checked against Citronella Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Citronella Oil against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Ivermectin ›
- Abemaciclib ›
- Testosterone ›
- Losartan Potassium ›
- Sertraline ›
- Acetaminophen ›
- Rosuvastatin ›
- Aspirin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Rivaroxaban ›
- Isotretinoin ›
- Tirzepatide ›
- Ibuprofen ›
- Warfarin Sodium ›
- Amlodipine Besylate ›
- Levothyroxine, Liothyronine ›
- Docusate ›
- Methamphetamine ›
- Prednisone ›
- Metformin ›
- Amitriptyline ›
- Tadalafil ›
- Semaglutide ›
- Lisdexamfetamine ›
- Hydroxyurea ›
- Valacyclovir ›
- Amphetamine ›
- Sumatriptan ›
- Propranolol ›
- Methotrexate ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Fluoxetine ›
- Azithromycin ›
- Pregabalin ›
- Doxycycline ›
- Gabapentin ›
- Acetaminophen, Aspirin, Caffeine ›
- Dextroamphetamine ›
- Naproxen ›
- Lamotrigine ›
- Bendamustine ›
- Quetiapine ›
- Clonazepam ›
- Acyclovir ›
- Buspirone ›
- Duloxetine ›
- Omeprazole ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Citronella Oil list.
Citronella Oil References
The 5 references that drive our Citronella Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
- Public Health Agency of Canada. Safety Tips on Using Personal Insect Repellents Available at: http://www.phac-aspc.gc.ca/wn-no/repellents-insectifuge_e.html. (Accessed 24 May 2005)
- Sajo ME, Song SB, Bajgai J, et al. Applicability of citronella oil (Cymbopogon winteratus) for the prevention of mosquito-borne diseases in the rural area of Tikapur, far-western Nepal. Rural Remote Health 2015;15(4):3532. Epub 2015 Nov 12. DOI
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Citronella Oil and Alpelisib Together: Common Questions
Is it safe to take Citronella Oil with Alpelisib?
Do Citronella Oil and Alpelisib have any of the same side effects?
Should I take Citronella Oil and Alpelisib at the same time of day?
Does Alpelisib interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.