Drug & supplement interaction

Citronella Oil + Duloxetine

Duloxetine brand names: Cymbalta, Drizalma Sprinkle, Irenka.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Citronella Oil and Duloxetine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Citronella Oil and Duloxetine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Duloxetine and Citronella Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Citronella Oil at all — not against Duloxetine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Citronella Oil safety at a glance

Citronella Oil overall Use caution Generally safe for topical and aromatic use, but it can irritate skin and should never be swallowed.
Pregnancy Use caution Limited safety data; use only sparingly on skin or in the air and check with your doctor first.
Breastfeeding Use caution Not well studied; avoid applying near the breast and consult your doctor before use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Duloxetine and Citronella Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Citronella Oil Itself Has Been Linked To

This is not an interaction — nothing below involves Duloxetine. It is the side-effect record for Citronella Oil on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Citronella Oil, this list is the first place to look.

  • A skin rash Additional detail

    “Topically, citronella oil is thought to be a skin sensitizer and can potentially cause contact dermatitis. Applying citronella oil 100% to the skin causes irritation or a burning sensation in about 12% of people.”

    Citronella Oil · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 13084. Public Health Agency of Canada. Safety Tips on Using Personal Insect Repellents Available at: http://www.phac-aspc.gc.ca/wn-no/repellents-insectifuge_e.html. (Accessed 24 May 2005)
    2. 97274. Sajo ME, Song SB, Bajgai J, et al. Applicability of citronella oil (Cymbopogon winteratus) for the prevention of mosquito-borne diseases in the rural area of Tikapur, far-western Nepal. Rural Remote Health 2015;15(4):3532. Epub 2015 Nov 12. DOI

Everything above comes from the Natural Medicines adverse-effect record for Citronella Oil — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Duloxetine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Duloxetine column appears here.

From our Q&A

Questions About Citronella Oil or Duloxetine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Citronella Oil or Duloxetine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Duloxetine

This page covers Citronella Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Duloxetine page lists 132 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Lithium (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 107 moderate · 20 minor.

Open the Duloxetine interaction page

How much people look this up

Where Citronella Oil and Duloxetine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Citronella Oil
Steady interest

#887 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Duloxetine
Top 5%

#87 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Citronella Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Citronella Oil and Duloxetine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Citronella Oil

What is Citronella Oil?

  • Insect and mosquito repellent
  • Aromatherapy and relaxation
  • Topical antimicrobial
  • Fragrance in soaps and household products
  • Skin and hair care products

Citronella oil is an essential oil made from a tropical grass and is best known as a natural insect repellent. Some evidence supports short-term mosquito protection, but it usually does not last as long as conventional repellents like DEET. It is meant for skin or air use, not for swallowing, and can irritate sensitive skin.

Cymbopogon nardus · Poaceae · Leaves and grass (steam-distilled essential oil) · Essential oil, sprays, lotions, candles, diffuser oil

An interaction check asks whether these two react with each other — it does not ask whether Citronella Oil is a good idea for someone in your situation. Here is what our Citronella Oil record says about it on its own.

Citronella Oil: dosing

There is no official standardized dose for citronella oil. For skin use, it is usually diluted with a carrier oil (such as coconut or almond oil) in commercial repellent products. For aromatherapy, a few drops are added to a diffuser or warm water.Because product strengths vary widely, the best approach is to follow the directions on the label and reapply repellent products as instructed.

From our Citronella Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Citronella Oil monograph & all interactions
Medication

About Duloxetine

What Is Duloxetine Used For?

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Duloxetine treats major depressive disorder and generalized anxiety disorder. It also treats pain conditions: diabetic peripheral neuropathic pain (nerve pain from diabetes), fibromyalgia, and chronic musculoskeletal pain (such as chronic low back pain and osteoarthritis pain).

Not every product is labeled for every age group. Cymbalta and some duloxetine products include generalized anxiety disorder in children 7 and older and fibromyalgia in teens 13 and older. Drizalma Sprinkle is labeled for fibromyalgia in adults. Some other duloxetine products do not carry the added pediatric information.

See full Duloxetine drug information
Keep checking

Other Drugs & Citronella Oil

Browse every other medication we’ve checked against Citronella Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Citronella Oil against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Citronella Oil list.

See the full Citronella Oil interactions page
See every supplement checked against Duloxetine, ranked by severity
Evidence & sources

Citronella Oil References

The 5 references that drive our Citronella Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  4. Public Health Agency of Canada. Safety Tips on Using Personal Insect Repellents Available at: http://www.phac-aspc.gc.ca/wn-no/repellents-insectifuge_e.html. (Accessed 24 May 2005)
  5. Sajo ME, Song SB, Bajgai J, et al. Applicability of citronella oil (Cymbopogon winteratus) for the prevention of mosquito-borne diseases in the rural area of Tikapur, far-western Nepal. Rural Remote Health 2015;15(4):3532. Epub 2015 Nov 12. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Citronella Oil and Duloxetine Together: Common Questions

Is it safe to take Citronella Oil with Duloxetine?
We do not list a known interaction between Citronella Oil and Duloxetine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Duloxetine interact with any supplements?
Yes. Duloxetine has documented interactions with 132 supplements in our database — Citronella Oil is not one of them. The Duloxetine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Citronella Oil monograph Uses, safety profile, and every drug interaction in one place Duloxetine drug information The full plain-English guide to this medication Duloxetine supplement interactions Every supplement checked against Duloxetine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Duloxetine and Citronella Oil?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.