Drug & supplement interaction

Clematis Recta + Cetirizine

Cetirizine brand names: Cetirizine, Zyrtec, Quzyttir.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Clematis Recta and Cetirizine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Clematis Recta and Cetirizine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cetirizine and Clematis Recta in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Clematis Recta at all — not against Cetirizine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Clematis Recta safety at a glance

Clematis Recta overall Use caution The raw plant is toxic and irritating; only highly diluted homeopathic forms are generally considered low-risk.
Pregnancy Likely Unsafe When the fresh plant is used orally. There is insufficient reliable information available for the safety of the dried plant; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe When the fresh plant is used orally. There is insufficient reliable information available for the safety of the dried plant; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cetirizine and Clematis Recta? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Clematis Recta and Cetirizine May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Diarrhea Additional detail

    Clematis Recta

    “Orally, fresh Clematis recta can cause colic, diarrhea, and severe irritation to the gastrointestinal tract (18).”

    Clematis Recta · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Cetirizine

    Listed in the ADVERSE REACTIONS section of the FDA label for Cetirizine. Read the label on DailyMed ›

Effects for Cetirizine come from the ADVERSE REACTIONS section of its FDA label; effects for Clematis Recta come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Clematis Recta in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When the fresh plant is used orally. There is insufficient reliable information available for the safety of the dried plant; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Clematis Recta or Cetirizine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Clematis Recta or Cetirizine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Cetirizine

This page covers Clematis Recta only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cetirizine page lists 100 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 78 moderate · 15 minor.

From our pharmacist’s overview on the Cetirizine page

“Cetirizine (Zyrtec) treats allergies, but even this newer antihistamine can make some people drowsy, and that weak spot is where most of its 100 documented supplement interactions land. Seventy-eight of the ingredients on this page add their own sedative pull on top of the drug's, and 7 of the 100 rate major, so treat this list with re…”

Reviewed by 2 · Jul 18, 2026

Open the Cetirizine interaction page

How much people look this up

Where Clematis Recta and Cetirizine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Clematis Recta
Steady interest

#877 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cetirizine
Top 25%

#579 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Clematis Recta reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Clematis Recta and Cetirizine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Clematis Recta

What is Clematis Recta?

  • Skin complaints and eruptions
  • Swollen or tender lymph glands
  • Urinary discomfort
  • Nerve pain
  • Men's groin and testicular discomfort (traditional homeopathic use)

Clematis recta is a flowering plant in the buttercup family that is mostly sold today as a homeopathic remedy. The fresh plant is toxic and irritating, and there is no reliable human evidence that it treats any condition, so it should be used cautiously and only under professional guidance.

Clematis recta · Ranunculaceae · Fresh leaves and stems (aerial parts), usually gathered before flowering · Homeopathic pellets, dilutions, and mother tinctures; rarely as topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Clematis Recta is a good idea for someone in your situation. Here is what our Clematis Recta record says about it on its own.

Clematis Recta: dosing

There is no established standard dose for Clematis recta. The raw plant is not recommended at all because it is toxic and irritating.When sold as a homeopathic remedy, it comes in standardized dilutions and potencies set by the manufacturer.

From our Clematis Recta monograph — the full record covers uses, side effects and every documented interaction.

Read the full Clematis Recta monograph & all interactions
Medication

About Cetirizine Injection

What Is Cetirizine Injection Used For?

Brand names: Cetirizine, Zyrtec, Quzyttir

Quzyttir (cetirizine injection) is approved to treat acute urticaria — a sudden outbreak of hives — in adults and in children 6 months of age and older. It is given by intravenous (IV) injection in a medically supervised setting.

Quzyttir is not recommended for children under 6 years of age who have impaired kidney or liver function.

See full Cetirizine Injection drug information
Keep checking

Other Drugs & Clematis Recta

Browse every other medication we’ve checked against Clematis Recta — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Clematis Recta References

The 1 references that drive our Clematis Recta monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Clematis Recta and Cetirizine Together: Common Questions

Is it safe to take Clematis Recta with Cetirizine?
We do not list a known interaction between Clematis Recta and Cetirizine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Clematis Recta and Cetirizine have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Cetirizine interact with any supplements?
Yes. Cetirizine has documented interactions with 100 supplements in our database — Clematis Recta is not one of them. The Cetirizine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Cetirizine and Clematis Recta?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.