Drug & supplement interaction

Costus + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

Aluminum Hydroxide, Aspirin, Magnesium Hydroxide brand name: Ascriptin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Costus and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Costus and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Aluminum Hydroxide, Aspirin, Magnesium Hydroxide and Costus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Costus at all — not against Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Costus safety at a glance

Costus overall Use caution Human safety data are limited, and quality and purity of products vary widely.
Pregnancy Avoid Traditionally believed to stimulate the uterus, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Aluminum Hydroxide, Aspirin, Magnesium Hydroxide and Costus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Costus Itself Has Been Linked To

This is not an interaction — nothing below involves Aluminum Hydroxide, Aspirin, Magnesium Hydroxide. It is the side-effect record for Costus on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Costus, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on Additional detail

    “Orally and topically, costus might cause allergic reactions, including contact dermatitis (11,73140,73155,73281,73284,73288).”

    Costus · Natural Medicines adverse-effect record, reported in dermatitis.

    6 sources cited
    1. 11. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
    2. 73140. Marzulli, F. N. and Maibach, H. I. Effects of vehicles and elicitation concentration in contact dermatitis testing. I. Experimental contact sensitization in humans. Contact Dermatitis 1976;2(6):325-329. PubMed
    3. 73155. Mitchell, J. C. Contact hypersensitivity to some perfume materials. Contact Dermatitis 1975;1(4):196-199. PubMed
    4. 73281. Benezra, C. and Epstein, W. L. Molecular recognition patterns of sesquiterpene lactones in costus-sensitive patients. Contact Dermatitis 1986;15(4):223-230. PubMed
    5. 73284. Mitchell, J. C. and Epstein, W. L. Contact hypersensitivity to a perfume material, Costus Absolute. The role of sesquiterpene lactones. Arch.Dermatol 1974;110(6):871-873. DOI
    6. 73288. Cheminat, A., Stampf, J. L., Benezra, C., Farrall, M. J., and Frechet, J. M. Allergic contact dermatitis to costus: removal of haptens with polymers. Acta Derm.Venereol. 1981;61(6):525-529. DOI
  • A skin rash Additional detail

    Recorded for Costus in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

Everything above comes from the Natural Medicines adverse-effect record for Costus — expand a row for the licensed statement it rests on. We haven’t matched Aluminum Hydroxide, Aspirin, Magnesium Hydroxide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Aluminum Hydroxide, Aspirin, Magnesium Hydroxide.

From our Q&A

Questions About Costus or Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Costus or Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

This page covers Costus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide page lists 255 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Danshen (major) and Piracetam (major).

By severity: 7 major · 211 moderate · 37 minor.

From our pharmacist’s overview on the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide page

“Ascriptin combines aspirin with two antacids, aluminum hydroxide and magnesium hydroxide, and the aspirin part already thins the blood on its own. That is why more than 200 of the 255 ingredients listed here can raise bleeding risk, and why this page deserves a careful read rather than a quick skim.”

Reviewed by 2 · Jul 18, 2026

Open the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction page

One more smart check

Taking Costus as Part of a Dietary Supplement Product? Check It for Interactions

We hold 113 real supplement products containing Costus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Costus. Even though Costus itself has no known interaction with Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Costus and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Costus
Top half

#602 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Aluminum Hydroxide, Aspirin, Magnesium Hydroxide
Top 1%

#14 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Costus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Costus and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Costus

What is Costus?

  • Digestive upset and gas
  • Cough and breathing complaints
  • Skin conditions (topical)
  • Worm and parasite remedies (traditional)
  • General tonic in traditional medicine

Costus (Saussurea costus) is a root used in Ayurvedic, Unani, and traditional Chinese medicine, mostly for digestive and respiratory complaints. High-quality human evidence is very limited, so its benefits are not well proven. Talk with a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Saussurea costus · Asteraceae · Dried roots and root essential oil · Dried root powder, capsules, decoctions (teas), essential oil, and topical pastes

An interaction check asks whether these two react with each other — it does not ask whether Costus is a good idea for someone in your situation. Here is what our Costus record says about it on its own.

Costus: dosing

There is no well-established or standardized dose of costus for any health condition. Traditional preparations vary widely, and the strength of commercial products is not consistent.If you choose to use a costus product, follow the directions on the label and do not exceed them. The essential oil is very concentrated and should not be taken by mouth without professional guidance.

From our Costus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Costus monograph & all interactions
Medication

About Aspirin

What Is Aspirin Used For?

Brand name: Ascriptin

Aspirin is used to temporarily relieve minor aches and pains from headaches, backaches, muscle aches, toothaches, menstrual cramps, the common cold, and minor arthritis pain. It also temporarily reduces fever.

Some coated aspirin tablet products note that, under a doctor's supervision, aspirin can help prevent another heart attack or stroke in adults who have already had one. Because of their delayed-release design, those coated products will not give fast relief for headaches or other symptoms needing quick relief.

See full Aspirin drug information
Keep checking

Other Drugs & Costus

Browse every other medication we’ve checked against Costus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Costus References

The 6 references that drive our Costus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Marzulli, F. N. and Maibach, H. I. Effects of vehicles and elicitation concentration in contact dermatitis testing. I. Experimental contact sensitization in humans. Contact Dermatitis 1976;2(6):325-329. PubMed
  3. Mitchell, J. C. Contact hypersensitivity to some perfume materials. Contact Dermatitis 1975;1(4):196-199. PubMed
  4. Benezra, C. and Epstein, W. L. Molecular recognition patterns of sesquiterpene lactones in costus-sensitive patients. Contact Dermatitis 1986;15(4):223-230. PubMed
  5. Mitchell, J. C. and Epstein, W. L. Contact hypersensitivity to a perfume material, Costus Absolute. The role of sesquiterpene lactones. Arch.Dermatol 1974;110(6):871-873. DOI
  6. Cheminat, A., Stampf, J. L., Benezra, C., Farrall, M. J., and Frechet, J. M. Allergic contact dermatitis to costus: removal of haptens with polymers. Acta Derm.Venereol. 1981;61(6):525-529. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Costus and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide Together: Common Questions

Is it safe to take Costus with Aluminum Hydroxide, Aspirin, Magnesium Hydroxide?
We do not list a known interaction between Costus and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interact with any supplements?
Yes. Aluminum Hydroxide, Aspirin, Magnesium Hydroxide has documented interactions with 255 supplements in our database — Costus is not one of them. The Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Aluminum Hydroxide, Aspirin, Magnesium Hydroxide and Costus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.