Drug & supplement interaction

Desert Parsley + Opicapone

Opicapone brand name: Ongentys.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Desert Parsley and Opicapone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Desert Parsley and Opicapone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Opicapone and Desert Parsley in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Desert Parsley at all — not against Opicapone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Desert Parsley safety at a glance

Desert Parsley overall Use caution Limited human safety data and a known risk of a measles-like skin rash in some users.
Pregnancy Avoid Not enough safety data; avoid use during pregnancy.
Breastfeeding Avoid Not enough safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Opicapone and Desert Parsley? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Opicapone’s Own FDA Label Lists

This is not an interaction — none of it involves Desert Parsley. These are the most notable effects listed in the ADVERSE REACTIONS section of Opicapone’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Hallucinations Worth acting on mentioned in 13.9% of FDA reports for Opicapone
  • Fainting Worth acting on
  • Confusion Worth acting on
  • Raised blood pressure Worth acting on
  • Weight gain
  • Weight loss
  • Dry mouth
  • Low blood pressure
  • Drowsiness
  • Trouble sleeping

Showing the 10 most notable of 12 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Opicapone. Read the label on DailyMed › Where a percentage is shown, it is the share of 2,261 voluntary FDA FAERS reports for Opicapone that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Desert Parsley’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Desert Parsley side to compare — that is a limit of the record, not a statement that Desert Parsley has no side effects.

Everything else you take

See Every Supplement That Interacts With Opicapone

This page covers Desert Parsley only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Opicapone page lists 58 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), St. John's Wort (major), Ayahuasca (moderate), Bitter Melon (moderate) and Black Horehound (moderate).

By severity: 2 major · 39 moderate · 17 minor.

From our pharmacist’s overview on the Opicapone page

“If you take opicapone (Ongentys) alongside levodopa for Parkinson's disease, don't skim this page. Two entries can genuinely undercut your treatment: St.”

Reviewed by 2 · Jul 18, 2026

Open the Opicapone interaction page

How much people look this up

Where Desert Parsley and Opicapone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Desert Parsley
Top half

#650 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Opicapone
Top half

#943 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Desert Parsley is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Desert Parsley reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Desert Parsley and Opicapone records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Desert Parsley

What is Desert Parsley?

  • Respiratory infections and colds
  • Cough and congestion
  • Flu-like illness
  • Immune support
  • Sore throat

Desert Parsley (Lomatium dissectum) is a root used in Native American and Western herbal traditions, mainly for colds, coughs, and respiratory infections. Modern scientific evidence in humans is very limited, and it can cause a widespread skin rash in some people, so use it cautiously and talk with your pharmacist or doctor first.

Lomatium dissectum · Apiaceae · Root · Tincture, capsules, dried root, tea, glycerite extract

An interaction check asks whether these two react with each other — it does not ask whether Desert Parsley is a good idea for someone in your situation. Here is what our Desert Parsley record says about it on its own.

Desert Parsley: dosing

There is no established standard dose for Desert Parsley. Traditional use varies widely depending on the form, whether it is a tincture, capsule, or tea.Because a safe and effective dose has not been defined in research, follow the directions on the product label and do not exceed them.

From our Desert Parsley monograph — the full record covers uses, side effects and every documented interaction.

Read the full Desert Parsley monograph & all interactions
Medication

About Opicapone

What Is Opicapone Used For?

Brand name: Ongentys

Ongentys (opicapone) is used alongside levodopa/carbidopa to treat Parkinson's disease in adults who experience 'off' episodes — periods when medication wears off and Parkinson's symptoms return before the next dose is due.

It is not used alone. Ongentys works as an add-on to help levodopa stay active longer, reducing the time patients spend in these 'off' states.

Most-Reported Side Effects for Opicapone

From FAERS, the FDA’s public side-effect reporting system (2,261 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hallucination 314 reports
Dyskinesia 306 reports
Fall 258 reports
On and off phenomenon 158 reports
Tremor 143 reports
See full Opicapone drug information
Keep checking

Other Drugs & Desert Parsley

Browse every other medication we’ve checked against Desert Parsley — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Desert Parsley against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Desert Parsley list.

See the full Desert Parsley interactions page
See every supplement checked against Opicapone, ranked by severity
Evidence & sources

Desert Parsley References

The 1 sources that drive our Desert Parsley monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Desert Parsley is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Desert Parsley and Opicapone Together: Common Questions

Is it safe to take Desert Parsley with Opicapone?
We do not list a known interaction between Desert Parsley and Opicapone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Opicapone interact with any supplements?
Yes. Opicapone has documented interactions with 58 supplements in our database — Desert Parsley is not one of them. The Opicapone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Desert Parsley monograph Uses, safety profile, and every drug interaction in one place Opicapone drug information The full plain-English guide to this medication Opicapone supplement interactions Every supplement checked against Opicapone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Opicapone and Desert Parsley?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.