Herb & supplement monograph

Maidenhair Fern Drug Interactions, Uses, Safety & More

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Reviewed by licensed pharmacists Sourced from Natural Medicines
Interaction report

Drugs that interact with Maidenhair Fern

0 medications have a known interaction with Maidenhair Fern, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Maidenhair Fern. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Maidenhair Fern combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Maidenhair Fern: Uses, Safety & Side Effects

The bottom line

Maidenhair fern is a traditional herb used mainly in teas and syrups for coughs and respiratory complaints, but high-quality human studies are lacking. Because its safety has not been well studied, it is best to use it cautiously and to avoid it during pregnancy and breastfeeding.

Scientific name
Adiantum capillus-veneris
Family
Pteridaceae
Part used
Fronds (leaves) and the whole above-ground plant
Common forms
Tea (infusion), syrup, dried herb, liquid extract, and as an ingredient in traditional cough preparations
People commonly use it for
  • Cough and respiratory complaints
  • Hair and scalp health
  • Cold and flu symptoms
  • Mild urinary complaints
  • Menstrual complaints

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Used traditionally in foods and teas, but modern safety data in humans are limited.

PregnancyUnsafe

When used orally. Maidenhair fern is contraindicated in pregnancy.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Maidenhair fern is a delicate fern known for its fine, fan-shaped leaflets and thin black stems. The most common type used in herbal products is Adiantum capillus-veneris, sometimes called Venus's hair fern. It grows in shady, moist places such as rocky cliffs, stream banks, and walls in many parts of the world, including Europe, Asia, Africa, and the Americas.

People have used maidenhair fern in traditional medicine for a very long time, mostly as a tea or syrup. It has been popular for soothing coughs and other breathing complaints. In some traditions it has also been used as a hair rinse and for general wellness.

Uses & effectiveness

Maidenhair fern is most often used as a folk remedy for coughs, colds, and chest congestion. It is also used traditionally for hair and scalp care, urinary complaints, and menstrual problems.

It is important to be honest about the evidence: there is very little high-quality human research on maidenhair fern. Most of what is known comes from traditional use and from laboratory or animal studies, which cannot tell us whether it truly works in people or how much to take. There is not enough reliable evidence to say it is effective for any specific health condition.

If you are considering it for a cough or any ongoing symptom, talk with a pharmacist or doctor first, since a lasting cough can have causes that need proper treatment.

How it works

Maidenhair fern contains plant compounds such as flavonoids, phenolic acids, tannins, and triterpenoids. In laboratory studies, extracts of the plant have shown antioxidant and possible antimicrobial activity, and the herb has traditionally been considered an expectorant that may help loosen mucus.

These proposed effects are mostly based on test-tube and animal research. It is not clear that the same effects happen in the human body at the amounts found in a tea or syrup, so these mechanisms should be seen as theories rather than proven facts.

Safety & precautions

Maidenhair fern has a long history of use in teas and traditional preparations, and is generally considered low-risk when used in small, food-like amounts. However, modern safety studies in humans are limited, so its safety at higher or concentrated doses is not well understood.

People with known allergies to ferns or related plants should be cautious. Anyone with a chronic medical condition, and children, should check with a healthcare provider before use.

Pregnancy and breastfeeding: Maidenhair fern has traditionally been linked to menstrual and uterine effects, and there is not enough safety data. To be safe, avoid it during pregnancy and while breastfeeding.

Side effects

Reported side effects are uncommon, partly because the herb has not been well studied. As with many herbal teas, possible effects include mild stomach upset or allergic reactions in sensitive people.

Stop using it and seek medical care if you notice signs of an allergic reaction such as rash, itching, swelling, or trouble breathing. Because product quality can vary, only use products from reputable sources.

Dosing

There is no standardized or well-established dose for maidenhair fern. Traditional use is mostly as a tea made from the dried fronds or as a syrup, but exact safe and effective amounts have not been confirmed by research.

If you choose to use it, follow the directions on the product label and do not exceed the suggested amount. A pharmacist can help you decide whether it is appropriate for you and review it alongside your other medicines and supplements.

Pregnancy & Breastfeeding

Maidenhair Fern & Pregnancy

Unsafe

When used orally. Maidenhair fern is contraindicated in pregnancy.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Maidenhair Fern & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 2 references that drive our Maidenhair Fern monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Maidenhair Fern

18 products in our database contain Maidenhair Fern. Open any to see its full ingredient list and every drug interaction we check.

Essential Detox by AN American Nutriceuticals Capsule 60 Vegetarian Capsule(s) View ingredients & interactions Essential Detox by AN American Nutriceuticals Capsule 60 Vegetarian Capsule(s) View ingredients & interactions Maidenhair Fern by Bixa Botanical Powder 200 Gram(s) · 7 Ounce(s) View ingredients & interactions Maidenhair Fern by Herbal Terra Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Maidenhair Fern by Herbal Terra Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Maidenhair Fern by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Maidenhair Fern by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Maidenhair Fern by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Maidenhair Fern 450 mg by TerraVita Premium Collection Capsule 100 Capsule(s) View ingredients & interactions Maidenhair Fern Alcohol Free by Herbal Terra Liquid 2 Fluid Ounce(s) · 60 mL View ingredients & interactions Maidenhair Fern Alcohol Free by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Maidenhair Fern Non-Alcohol by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Maidenhair Fern Powder by TerraVita Premium Collection Powder 1 Ounce(s) View ingredients & interactions Maidenhair Fern Powder by TerraVita Premium Collection Powder 4 Ounce(s) View ingredients & interactions Profollica Plus with Millet Extract by Leading Edge Health Capsule 60 Capsule(s) View ingredients & interactions Essential Detox by AN American Nutriceuticals Tablet Or Pill 60 Tablet(s) Off market View ingredients & interactions Essential Detox by AN American Nutriceuticals Tablet Or Pill 60 Tablet(s) Off market View ingredients & interactions Maidenhair Fern Non-Alcohol by Hawaii Pharm Liquid 4 Fluid Ounce(s) · 120 mL Off market View ingredients & interactions
Pharmacist Counseling Corner

Maidenhair Fern: Common Questions

Does Maidenhair Fern interact with prescription medications?
We do not currently list any known drug interactions for Maidenhair Fern. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Maidenhair Fern interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Maidenhair Fern with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Maidenhair Fern interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Maidenhair Fern used for?
It is used traditionally as a tea or syrup, mostly for coughs and respiratory complaints, and also as a hair rinse. There is little strong human evidence that it works for any specific condition.
Is Maidenhair Fern safe to take?
It has a long history of use in small, tea-like amounts and is generally considered low-risk, but modern safety studies are limited. It is best used cautiously and discussed with a pharmacist or doctor.
Can I use Maidenhair Fern during pregnancy or breastfeeding?
No. Because it has traditionally been linked to menstrual and uterine effects and there is not enough safety data, it is best to avoid it during pregnancy and breastfeeding.
How is Maidenhair Fern usually taken?
It is most commonly taken as a tea made from the dried leaves or as part of a cough syrup. There is no standardized dose, so follow the product label and check with a healthcare provider.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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