Profollica Plus with Millet Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Profollica Plus with Millet Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Profollica Plus with Millet Extract is a dietary supplement by Leading Edge Health with 5 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Cysteine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Profollica Plus with Millet Extract by Leading Edge Health
Ask about any prescription or over-the-counter medication and we check it for interactions with Profollica Plus with Millet Extract by Leading Edge Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Profollica Plus with Millet Extract by Leading Edge Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Profollica Plus contains 5 active ingredients. Biotin is a B vitamin that supports hair and nail health; it's well established for treating biotin deficiency, though evidence for hair loss conditions is limited or inconclusive.
L-cysteine is an amino acid thought to play a role in hair structure. Pantothenic acid (vitamin B5) rounds out the B-vitamin group.
Millet extract and maidenhair fern are herbal components included for their traditional use in hair health, though modern research on their effectiveness is sparse. The product also contains inactive ingredients such as maltodextrin, vegetable cellulose, and silica for texture and stability.
Does it work?
Strong evidence
The evidence behind this product's ingredients is mixed. Biotin is effective for biotin deficiency itself, but the data show it's possibly ineffective for hair loss conditions like alopecia areata and seborrheic dermatitis.
Pantothenic acid is effective for pantothenic acid deficiency but has insufficient evidence for most other uses. L-cysteine, millet extract, and maidenhair fern all lack reliable evidence in our data — we don't have enough information to rate whether they work for their intended purpose.
How safe is it?
Well-documented data
Biotin is generally well tolerated, even at higher doses, because your body excretes excess in urine; rarely, high-dose biotin has caused mild diarrhea. Pantothenic acid is also generally well tolerated at typical supplement doses.
L-cysteine is well tolerated in food amounts, but its long-term safety at supplement doses isn't well studied — discuss high-dose use with your doctor. Maidenhair fern was traditionally linked to effects on the menstrual cycle and uterus, so avoid it during pregnancy; there's also insufficient safety data for breastfeeding.
Biotin and pantothenic acid are rated likely safe in pregnancy and lactation.
Meds to double-check
Moderate interaction found
If you take antidiabetes drugs (insulin, metformin, sulfonylureas, or others), check your specific medications before starting this product — L-cysteine may increase the risk of low blood sugar. For the other ingredients we could check, no interactions are documented in our data.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is aimed at hair health with a mix of B vitamins and plant extracts. If you take antidiabetes medications, check with your pharmacist first because L-cysteine may affect blood sugar.
If you're pregnant or breastfeeding, talk with your doctor — maidenhair fern is not recommended in pregnancy, and most ingredients lack robust safety data.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Profollica Plus with Millet Extract, straight from the product label.
| Brand | Leading Edge Health |
|---|---|
| Barcode (UPC) | 628043006256 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2022 |
| DSLD ID | 272171 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Profollica Plus with Millet Extract by Leading Edge Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Biotin | 200 mcg | 67% |
| L-Cysteine | 6 mcg | -- |
| Pantothenic Acid | 30 mg | 300% |
| Millet Extract | 420 mcg | -- |
| Maidenhair Fern | 100 mcg | -- |
Other ingredients: Maltodextrin, Vegetable Cellulose, Vanillin, Medium Chain Triglycerides, Silicon Dioxide, Vegetable Stearate, Titanium Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: 2 capsules daily preferably with meals or as directed by a healthcare professional.
Precautions
Caution: Do not exceed recommended dose.
This product is not intended for pregnant or nursing mothers, children under the age of 18, or persons with a known medical condition including any cardiovascular disorder, hypertension (low blood pressure) and Parkinson's disease.
This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish, and crustacean shellfish.
This product is not intended for pregnant or nursing mothers, children under the age of 18, or persons with a known medical condition including any cardiovascular disorder, hypertension (low blood pressure) and Parkinson's disease. Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
Storage
Store at room temperature.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Please recycle.
Seals/Symbols
Made in USA GMP Sourced From A GMP Certified Facility
Formulation
By GenF2O All-natural treatment to reduce hair loss and increase growth Guaranteed 100% Premium Quality
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Profollica Plus with Millet Extract by Leading Edge Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Profollica Plus with Millet Extract by Leading Edge Health
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Biotin
No knowninteractions
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...
Biotin monograph & interactionsL-Cysteine
Interacts with86 drugs
L-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and su...
L-Cysteine monograph & interactionsPantothenic Acid
No knowninteractions
Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...
Pantothenic Acid monograph & interactionsMillet Extract
Maidenhair Fern
No knowninteractions
Maidenhair fern is a traditional herb used mainly in teas and syrups for coughs and respiratory complaints, but high-quality human studies are lacking...
Maidenhair Fern monograph & interactionsOther (inactive) ingredients: Maltodextrin, Vegetable Cellulose, Vanillin, Medium Chain Triglycerides, Silicon Dioxide, Vegetable Stearate, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.
Profollica Plus with Millet Extract by Leading Edge Health Drug Interactions
HelloPharmacist Interaction Report
Profollica Plus with Millet Extract from Leading Edge Health does interact with medications — specifically, one ingredient affects blood sugar control.
L-cysteine may increase the risk of low blood sugar (hypoglycemia) if you're taking antidiabetes drugs. The effect is theorized based on animal research showing L-cysteine can lower blood sugar, so talk with your doctor or pharmacist if you use insulin or other diabetes medications.
Read the full breakdown — every affected drug type, severity by severity
Biotin and pantothenic acid, the other checked ingredients in this product, have no interactions documented in our data. Millet extract could not be checked — we hold no data for it.
Maidenhair fern also shows no documented interactions.
Altogether, these interactions span 85 individual medications. Use the medication checker on this page to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Profollica Plus with Millet Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Profollica Plus with Millet Extract interact with 86 drugs. Click any drug to see the details.
1 of the 5 ingredients in Profollica Plus with Millet Extract interact with drugs. Each result below shows which ingredient is responsible. L-Cysteine
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Glipizide, Metformin interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with Profollica Plus with Millet Extract — through 1 ingredient. Tap an ingredient for the detail:
L-cysteineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine + Glucagon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Profollica Plus with Millet Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Cysteine
Antidiabetes Drugs
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that L-cysteine can have hypoglycemic effects.
Brand information
Manufacturer and brand details for Profollica Plus with Millet Extract, from the product label.
Leading Edge Health
See all Leading Edge Health products- Name
- Leading Edge Health
- Street Address
- 100 Fidelitone Way
- City
- Elizabethton
- State
- TN
- ZipCode
- 37643
- Web Address
- www.leadingedgehealth.com
Profollica Plus with Millet Extract by Leading Edge Health: Common Questions
Does Profollica Plus with Millet Extract by Leading Edge Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe during pregnancy?
Is this safe while breastfeeding?
Can biotin cause side effects?
Does L-cysteine actually help with hair loss?
What is maidenhair fern and why is it in here?
Why can't you check millet extract for interactions?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Profollica Plus with Millet Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Profollica Plus with Millet Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Biotin
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...
Read the full Biotin monograph → Herb & supplement monographL-cysteine
Interacts with 86 drugsL-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and supplements are usually well tolerated, bu...
Read the full L-cysteine monograph → Herb & supplement monographPantothenic Acid
Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...
Read the full Pantothenic Acid monograph → Herb & supplement monographMaidenhair Fern
Maidenhair fern is a traditional herb used mainly in teas and syrups for coughs and respiratory complaints, but high-quality human studies are lacking. Because its safety has not been well s...
Read the full Maidenhair Fern monograph →Sources & How We Checked
Profollica Plus with Millet Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 19 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Biotin 4 references
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
- Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed
L-cysteine 2 references
- Dowlati Y, Maheux M, Meyer JH. The effect of oral L-cysteine on breast milk and plasma cysteine concentrations. Neuropsychiatr Dis Treat 2020;16:3163-3172.
- Lee S, Han KH, Nakamura Y, et al. Dietary L-cysteine improves the antioxidative potential and lipid metabolism in rats fed a normal diet. Biosci Biotechnol Biochem 2013;77(7):1430-4.
Pantothenic Acid 11 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
- Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
- Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
- Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
- Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
- Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
- Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
- Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed
Maidenhair Fern 2 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
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