Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

VigRX Incontinix Ingredients & Drug Interactions

by Leading Edge Health

VigRX Incontinix label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking VigRX Incontinix against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

VigRX Incontinix is a dietary supplement by Leading Edge Health with 3 active ingredients. Its ingredients are commonly taken for fluid retention (mild diuretic), urinary and bladder concerns, hair, skin, and nail support.Based on those ingredients, 188 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horsetail Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against VigRX Incontinix by Leading Edge Health

Ask about any prescription or over-the-counter medication and we check it for interactions with VigRX Incontinix by Leading Edge Health — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of VigRX Incontinix by Leading Edge Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Urox Proprietary Blend” is a proprietary blend — the label gives one combined amount (840 mg) without saying how much of each component you get.

VigRX Incontinix contains 3 active ingredients. Horsetail aerial parts extract is included for urinary incontinence, though the evidence for its effectiveness isn't established in our data.

The product also contains Cratevox Three-leaf Caper stem bark extract and Lindera Root Extract, ingredients we could not evaluate for interactions or effects. The capsules also hold inactive ingredients — hydroxypropylmethylcellulose, rice flour, and silica — which are standard binders and fillers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Horsetail's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: bladder tone and healthy bladder control.
  • We looked for evidence on: Urinary incontinence, Overactive bladder, Urge incontinence, Stress incontinence.
  • The closest evidence on file: Horsetail is rated "Insufficient Reliable Evidence To Rate" for Urinary incontinence (Natural Medicines).

Our data rates horsetail's effectiveness for urinary incontinence as insufficient reliable evidence. The same goes for the other claims sometimes made for this product: obesity, tonsillitis, and hair loss (androgenic alopecia) all lack established evidence in our monographs.

If you're considering this product for any of these uses, the research backing isn't solid enough yet.

The evidence, ingredient by ingredient Horsetail

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horsetail is generally well tolerated in short-term use by healthy adults, but long-term use carries real risks we don't fully understand. The most common side effects in trials were abdominal bloating, increased bowel movements, and nausea.

Crude horsetail contains a compound called thiaminase that can cause thiamine (vitamin B1) deficiency if you take it for a long time — though Canadian horsetail products are required to be tested and certified free from this risk. There's also a case report of a severe skin reaction after topical horsetail application.

The safety data advises against use during pregnancy and while breastfeeding. The other two active ingredients have insufficient safety data on file.

Side effects, ingredient by ingredient Horsetail

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horsetail.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 188 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start VigRX Incontinix, double-check with your pharmacist if you take any HIV antiretroviral drugs (especially NRTIs like zidovudine or lamivudine, or efavirenz), antidiabetes medications, diuretics (water pills), or lithium. Horsetail in this product has documented Moderate-severity interactions with all of these drug types.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're dealing with urinary incontinence, but the evidence backing it isn't strong. If you take blood sugar medications, water pills, lithium, or HIV antiretroviral drugs — especially NRTIs or efavirenz — you'll want to check with your pharmacist first; horsetail can interfere with how these work.

Talk with your doctor or pharmacist about whether it's right for you and how long it's safe to use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about VigRX Incontinix, straight from the product label.

Brand Leading Edge Health
Barcode (UPC) 628043009127
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 306926
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for VigRX Incontinix by Leading Edge Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
628043009127
IngredientAmount% DV
Cratevox Three-leaf Caper (Crateva nurvala) stem bark extract0 NP--
Urox Proprietary Blend840 mg--
Lindera Root Extract0 NP--
Horsetail Aerial Parts Extract0 NP--

Other ingredients: Hydroxypropylmethylcellulose, Rice Flour, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

The benefits of Incontinix Efficient control of the bladder requires healthy bladder tone and function. Incontinix supports and improves bladder tone and promotes healthy bladder control in men and women. Results are seen after 2-4 weeks of use.

Incontinix is a unique patented Australian formula that has been shown in clinical research to support healthy bladder function and rejuvenate tone.

Premium Quality 100% Guaranteed

Bladder control Clinically proven

Formula

Incontinix contains specialized herbal extracts of horsetail, crateva and lindera, which all have a long history of traditional herbal use for healthy bladder function. Results are seen after 2-4 weeks of use.

Scientifically formulated with Urox

Precautions

Customers are cautioned to read all labels and follow all directions. You should always consult with your healthcare practitioner before using this or any such product. Do not use if tamper-evident seal is missing or broken.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Please recycle

Seals/Symbols

Made in USA Sourced from a GMP Certified Facility

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 2 capsules daily. For faster effects, take 2 capsules twice daily for the first month of use.

Brand IP Statement(s)

US Patent No. 9,452,191 Urox and Cratevox are trademarks of Seipei Group Pty Ltd.

Storage

Store at room temperature.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

VigRX Incontinix by Leading Edge Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

VigRX Incontinix label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in VigRX Incontinix by Leading Edge Health

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Urox Proprietary Blend

840 mg per serving

Other (inactive) ingredients: Hydroxypropylmethylcellulose, Rice Flour, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

VigRX Incontinix by Leading Edge Health Drug Interactions

Want to check YOUR meds against VigRX Incontinix?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
188Drugs
188 Moderate

Ingredients driving the most interactions

Horsetail Aerial Parts Extract 188

Individual Drug Interactions

The ingredients in VigRX Incontinix interact with 188 drugs. Click any drug to see the details.

1 of the 3 ingredients in VigRX Incontinix interact with drugs. Each result below shows which ingredient is responsible. Horsetail Aerial Parts Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in VigRX Incontinix with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horsetail Aerial Parts Extract5 drug types · 188 drugs

Antidiabetes Drugs

Theoretically, taking horsetail with antidiabetes drugs might increase the risk of hypoglycemia.
Equisetum myriochaetum has demonstrated hypoglycemic activity in clinical research. In an animal diabetic model, Equisetum giganteum had hypoglycemic effects. It is unclear whether other horsetail species have hypoglycemic effects.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Laboratory research shows that various species of horsetail have diuretic properties. Due to its diuretic effects, there has been concern that taking horsetail along with potassium-depleting diuretics might increase the risk for hypokalemia. However, pharmacokinetic research in humans shows that taking horsetail 900 mg daily for 4 days does not affect urinary excretion of electrolytes, including potassium and sodium, despite having a diuretic effect similar to taking hydrochlorothiazide 25 mg daily. It is unclear if taking horsetail for a longer duration would affect electrolyte levels. Until more is known, use with caution.

Likelihood Possible Evidence D
Efavirenz (Sustiva)

Theoretically, horsetail might decrease the levels and clinical effects of efavirenz.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral regimen that included efavirenz. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing horsetail, the viral loads became undetectable in both cases. The exact mechanism of this interaction is unknown. It is also unclear if this interaction is specific to efavirenz or if it is related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, horsetail might increase the levels and adverse effects of lithium.
Animal research suggests that horsetail has diuretic properties. Theoretically, due to these potential diuretic effects, horsetail might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Nucleoside Reverse Transcriptase Inhibitors (Nrtis)

Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral therapy. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing the supplement, the viral loads became undetectable in both cases. The exact mechanism of these interactions is unknown. It is also unclear if these interactions are specific to NRTIs or if they are related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Horsetail Aerial Parts Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for VigRX Incontinix, from the product label.

Leading Edge Health

See all Leading Edge Health products
Name
Leading Edge Health
Street Address
100 Fidelitone Way
City
Elizabethton
State
TN
ZipCode
37643
Web Address
www.vigfx.com
Pharmacist Counseling Corner

VigRX Incontinix by Leading Edge Health: Common Questions

Does VigRX Incontinix by Leading Edge Health interact with any medications?
Yes. Based on its ingredients, VigRX Incontinix has a known interaction with 188 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
VigRX Incontinix contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against use during pregnancy and while breastfeeding. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor before considering this product.
What are the side effects?
The most common ones from clinical research are bloating, more frequent bowel movements, and nausea. Horsetail also contains a compound that can cause vitamin B1 deficiency with long-term use, though Canadian products are tested to be free of this risk.
Does this actually work for incontinence?
Our data rates horsetail's effectiveness for urinary incontinence as insufficient reliable evidence — meaning the research backing isn't solid enough yet to say whether it works.
Why can't you check all three ingredients for interactions?
We hold no interaction data for Cratevox Three-leaf Caper stem bark extract or Lindera Root Extract. That doesn't mean they're safe — it means we haven't found published monographs to check them against.
Is this safe to take long-term?
The safety data suggests it's okay for short-term use by healthy adults, but long-term use carries risks we don't fully understand yet. Talk with your pharmacist about how long you should take it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if VigRX Incontinix is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

VigRX Incontinix label
Go deeper

The Full Monographs Behind VigRX Incontinix’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horsetail

Interacts with 188 drugs

Horsetail is a traditional herb most often used as a mild diuretic and for hair, nail, and bone support, but high-quality human evidence is limited. It can cause thiamine (vitamin B1) loss w...

Read the full Horsetail monograph →
Sources

Sources & How We Checked

VigRX Incontinix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horsetail 14 references
  1. Sudan BJ. Seborrhoeic dermatitis induced by nicotine of horsetails (Equisetum arvense L.). Contact Dermatitis 1985;13:201-2.
  2. Perez Gutierrez RM, Laguna GY, Walkowski A. Diuretic activity of Mexican equisetum. J Ethnopharmacol 1985;14:269-72. PubMed
  3. Lemus I, Garcia R, Erazo S, et al. Diuretic activity of an Equisetum bogotense tea (Platero herb): evaluation in healthy volunteers. J Ethnopharmacol 1996;54:55-8. PubMed
  4. Revilla MC, Andrade-Cetto A, Islas S, Wiedenfeld H. Hypoglycemic effect of Equisetum myriochaetum aerial parts on type 2 diabetic patients. J Ethnopharmacol 2002;81:117-20. PubMed
  5. Tiktinskii, O. L. and Bablumian, I. A. [Therapeutic action of Java tea and field horsetail in uric acid diathesis]. Urol.Nefrol.(Mosk) 1983;3(1):47-50.
  6. Henderson JA, Evans EV, and McIntosh RA. The antithiamine action of Equisetum. J Amer Vet Med Assoc 1952;120:375-378.
  7. Carneiro DM, Freire RC, Honório TC, Zoghaib I, Cardoso FF, Tresvenzol LM, de Paula JR, Sousa AL, Jardim PC, da Cunha LC. Randomized, Double-Blind Clinical Trial to Assess the Acute Diuretic Effect of Equisetum arvense (Field Horsetail) in Healthy Voluntee
  8. Klnçalp S, Ekiz F, Basar Ö, Coban S, Yüksel O. Equisetum arvense (Field Horsetail)-induced liver injury. Eur J Gastroenterol Hepatol. 2012 Feb;24(2):213-4. PubMed
  9. Ortega García JA, Angulo MG, Sobrino-Najul EJ, Soldin OP, Mira AP, Martínez-Salcedo E, Claudio L. Prenatal exposure of a girl with autism spectrum disorder to 'horsetail' (Equisetum arvense) herbal remedy and alcohol: a case report. J Med Case Rep. 2011 M PubMed
  10. Cordova E, Morganti L, Rodriguez C. Possible Drug-Herb Interaction between Herbal Supplement Containing Horsetail (Equisetum arvense) and Antiretroviral Drugs. J Int Assoc Provid AIDS Care. 2017;16(1):11-13.
  11. García Gavilán MD, Moreno García AM, Rosales Zabal JM, Navarro Jarabo JM, Sánchez Cantos A. Case of drug-induced acute pancreatitis produced by horsetail infusions. Rev Esp Enferm Dig. 2017 Apr;109(4):301-304. PubMed
  12. Vieira GT, de Oliveira TT, Carneiro MAA, et al. Antidiabetic effect of Equisetum giganteum L. extract on alloxan-diabetic rabbit. J Ethnopharmacol. 2020;260:112898. PubMed
  13. Health Canada. Organism-Equisetum arvense. Available at: http://webprod.hc-sc.gc.ca/nhpid-bdipsn/ingredReq.do?id=6117&lang=eng. Accessed 21-July 2021.
  14. Bates D, Duong TB, Kheyson S, Moore K. Hyponatremia Secondary to Decreased Oral Intake and SIADH and Possibly Exacerbated by Horsetail (Equisetum arvense). Can J Hosp Pharm 2021;74(4):386-389. PubMed

See these in context on the Horsetail monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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