Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

VigRX Incontinix Ingredients & Drug Interactions

by Leading Edge Health

VigRX Incontinix label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking VigRX Incontinix against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

VigRX Incontinix is a dietary supplement by Leading Edge Health with 3 active ingredients. Its ingredients are commonly taken for fluid retention (mild diuretic), urinary and bladder concerns, hair, skin, and nail support.Based on those ingredients, 188 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horsetail Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against VigRX Incontinix by Leading Edge Health

Ask about any prescription or over-the-counter medication and we check it for interactions with VigRX Incontinix by Leading Edge Health — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of VigRX Incontinix by Leading Edge Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Urox Proprietary Blend” is a proprietary blend — the label gives one combined amount (840 mg) without saying how much of each component you get.

VigRX Incontinix contains three active ingredients: Cratevox Three-leaf Caper stem bark extract, a proprietary blend called Urox (made up of several component ingredients), and Lindera Root Extract, plus Horsetail Aerial Parts Extract. The product also includes inactive ingredients—hydroxypropylmethylcellulose, rice flour, and silica—which act as capsule material and fillers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Horsetail's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: bladder tone and healthy bladder control.
  • We looked for evidence on: Urinary incontinence, overactive bladder, stress incontinence, urgency incontinence.
  • The closest evidence on file: Horsetail is rated "Insufficient Reliable Evidence To Rate" for Urinary incontinence (Natural Medicines).

The evidence on horsetail for urinary incontinence—this product's stated purpose—is insufficient to rate reliably. We also hold insufficient evidence for its use in obesity, tonsillitis, and male-pattern hair loss.

If you're considering this product for incontinence, talk with your doctor or pharmacist about what the current research actually supports for your situation.

The evidence, ingredient by ingredient Horsetail

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horsetail is generally well tolerated short-term in healthy adults, but long-term use carries real risks. The most common side effects reported in limited clinical research are abdominal bloating, increased bowel movements, and nausea.

Crude horsetail contains thiaminase, an enzyme that can deplete thiamine (vitamin B1) with prolonged use—though Canadian horsetail products are required to be free from thiaminase-like activity. There is also one case report of seborrheic dermatitis from topical horsetail application.

During pregnancy, there isn't enough safety data—the product should be avoided. The same goes for breastfeeding.

Two of the three active ingredients (Cratevox and Lindera) have no safety data on file for us to review.

Side effects, ingredient by ingredient Horsetail

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horsetail.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 188 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking VigRX Incontinix, double-check with your doctor or pharmacist if you take HIV drugs (NRTIs or efavirenz), antidiabetes medications, diuretics (water pills), or lithium. Horsetail can reduce how well some HIV drugs work and may affect blood sugar control, potassium levels, and lithium levels.

These are all Moderate-severity interactions that may need dosing adjustments or closer monitoring.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to someone looking for natural support for urinary symptoms, but the evidence for its effectiveness isn't established in our data. The main concern is if you take HIV medications, antidiabetes drugs, diuretics, or lithium—horsetail can meaningfully interact with those.

If you're pregnant or breastfeeding, the safety data advises against it. Talk with your doctor or pharmacist before adding this to your routine, especially if you're on any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about VigRX Incontinix, straight from the product label.

Brand Leading Edge Health
Barcode (UPC) 628043009127
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 306926
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for VigRX Incontinix by Leading Edge Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
628043009127
IngredientAmount% DV
Cratevox Three-leaf Caper (Crateva nurvala) stem bark extract0 NP--
Urox Proprietary Blend840 mg--
Lindera Root Extract0 NP--
Horsetail Aerial Parts Extract0 NP--

Other ingredients: Hydroxypropylmethylcellulose, Rice Flour, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

The benefits of Incontinix Efficient control of the bladder requires healthy bladder tone and function. Incontinix supports and improves bladder tone and promotes healthy bladder control in men and women. Results are seen after 2-4 weeks of use.

Incontinix is a unique patented Australian formula that has been shown in clinical research to support healthy bladder function and rejuvenate tone.

Premium Quality 100% Guaranteed

Bladder control Clinically proven

Formula

Incontinix contains specialized herbal extracts of horsetail, crateva and lindera, which all have a long history of traditional herbal use for healthy bladder function. Results are seen after 2-4 weeks of use.

Scientifically formulated with Urox

Precautions

Customers are cautioned to read all labels and follow all directions. You should always consult with your healthcare practitioner before using this or any such product. Do not use if tamper-evident seal is missing or broken.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Please recycle

Seals/Symbols

Made in USA Sourced from a GMP Certified Facility

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 2 capsules daily. For faster effects, take 2 capsules twice daily for the first month of use.

Brand IP Statement(s)

US Patent No. 9,452,191 Urox and Cratevox are trademarks of Seipei Group Pty Ltd.

Storage

Store at room temperature.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

VigRX Incontinix by Leading Edge Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

VigRX Incontinix label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in VigRX Incontinix by Leading Edge Health

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Urox Proprietary Blend

840 mg per serving

Other (inactive) ingredients: Hydroxypropylmethylcellulose, Rice Flour, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

VigRX Incontinix by Leading Edge Health Drug Interactions

Want to check YOUR meds against VigRX Incontinix?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
188Drugs
188 Moderate

Ingredients driving the most interactions

Horsetail Aerial Parts Extract 188

Individual Drug Interactions

The ingredients in VigRX Incontinix interact with 188 drugs. Click any drug to see the details.

1 of the 3 ingredients in VigRX Incontinix interact with drugs. Each result below shows which ingredient is responsible. Horsetail Aerial Parts Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in VigRX Incontinix with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horsetail Aerial Parts Extract5 drug types · 188 drugs

Antidiabetes Drugs

Theoretically, taking horsetail with antidiabetes drugs might increase the risk of hypoglycemia.
Equisetum myriochaetum has demonstrated hypoglycemic activity in clinical research. In an animal diabetic model, Equisetum giganteum had hypoglycemic effects. It is unclear whether other horsetail species have hypoglycemic effects.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Laboratory research shows that various species of horsetail have diuretic properties. Due to its diuretic effects, there has been concern that taking horsetail along with potassium-depleting diuretics might increase the risk for hypokalemia. However, pharmacokinetic research in humans shows that taking horsetail 900 mg daily for 4 days does not affect urinary excretion of electrolytes, including potassium and sodium, despite having a diuretic effect similar to taking hydrochlorothiazide 25 mg daily. It is unclear if taking horsetail for a longer duration would affect electrolyte levels. Until more is known, use with caution.

Likelihood Possible Evidence D
Efavirenz (Sustiva)

Theoretically, horsetail might decrease the levels and clinical effects of efavirenz.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral regimen that included efavirenz. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing horsetail, the viral loads became undetectable in both cases. The exact mechanism of this interaction is unknown. It is also unclear if this interaction is specific to efavirenz or if it is related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, horsetail might increase the levels and adverse effects of lithium.
Animal research suggests that horsetail has diuretic properties. Theoretically, due to these potential diuretic effects, horsetail might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Nucleoside Reverse Transcriptase Inhibitors (Nrtis)

Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral therapy. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing the supplement, the viral loads became undetectable in both cases. The exact mechanism of these interactions is unknown. It is also unclear if these interactions are specific to NRTIs or if they are related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Horsetail Aerial Parts Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for VigRX Incontinix, from the product label.

Leading Edge Health

See all Leading Edge Health products
Name
Leading Edge Health
Street Address
100 Fidelitone Way
City
Elizabethton
State
TN
ZipCode
37643
Web Address
www.vigfx.com
Pharmacist Counseling Corner

VigRX Incontinix by Leading Edge Health: Common Questions

Does VigRX Incontinix by Leading Edge Health interact with any medications?
Yes. Based on its ingredients, VigRX Incontinix has a known interaction with 188 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
VigRX Incontinix contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is horsetail, and what does it do in this product?
Horsetail is a plant extract used in traditional medicine for various purposes, including urinary and bone health. It's one of the active ingredients in VigRX Incontinix, but the reliable evidence for what it actually does for incontinence is insufficient.
Can I take this if I'm pregnant or breastfeeding?
No. There isn't enough safety data for horsetail during pregnancy or while breastfeeding, and the safety data advises against both. Talk with your doctor or pharmacist about safer alternatives if you need support during this time.
What are the most common side effects?
The most common side effects reported from horsetail are abdominal bloating, increased bowel movements, and nausea. Long-term use can also deplete thiamine (vitamin B1), especially with crude horsetail products.
Does this product work for urinary incontinence?
The evidence on horsetail for urinary incontinence is insufficient to rate reliably, so we can't say whether it works based on the data we hold. Your doctor or pharmacist can discuss what research actually exists and whether this is the right choice for you.
What inactive ingredients are in this capsule?
The capsule contains hydroxypropylmethylcellulose (a plant-based capsule material), rice flour, and silica—all standard inactive fillers and binders.
Why can't you check the other two ingredients for drug interactions?
We don't hold monograph data for Cratevox Three-leaf Caper or Lindera Root Extract, so we weren't able to check them against medication databases. That doesn't mean they're safe to use with your drugs—it just means we don't have the information. Mention all three ingredients to your pharmacist or doctor when you ask about this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

VigRX Incontinix label
Go deeper

The Full Monographs Behind VigRX Incontinix’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horsetail

Interacts with 188 drugs

Horsetail is a traditional herb most often used as a mild diuretic and for hair, nail, and bone support, but high-quality human evidence is limited. It can cause thiamine (vitamin B1) loss w...

Read the full Horsetail monograph →
Sources

Sources & How We Checked

VigRX Incontinix's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horsetail 14 references
  1. Sudan BJ. Seborrhoeic dermatitis induced by nicotine of horsetails (Equisetum arvense L.). Contact Dermatitis 1985;13:201-2.
  2. Perez Gutierrez RM, Laguna GY, Walkowski A. Diuretic activity of Mexican equisetum. J Ethnopharmacol 1985;14:269-72. PubMed
  3. Lemus I, Garcia R, Erazo S, et al. Diuretic activity of an Equisetum bogotense tea (Platero herb): evaluation in healthy volunteers. J Ethnopharmacol 1996;54:55-8. PubMed
  4. Revilla MC, Andrade-Cetto A, Islas S, Wiedenfeld H. Hypoglycemic effect of Equisetum myriochaetum aerial parts on type 2 diabetic patients. J Ethnopharmacol 2002;81:117-20. PubMed
  5. Tiktinskii, O. L. and Bablumian, I. A. [Therapeutic action of Java tea and field horsetail in uric acid diathesis]. Urol.Nefrol.(Mosk) 1983;3(1):47-50.
  6. Henderson JA, Evans EV, and McIntosh RA. The antithiamine action of Equisetum. J Amer Vet Med Assoc 1952;120:375-378.
  7. Carneiro DM, Freire RC, Honório TC, Zoghaib I, Cardoso FF, Tresvenzol LM, de Paula JR, Sousa AL, Jardim PC, da Cunha LC. Randomized, Double-Blind Clinical Trial to Assess the Acute Diuretic Effect of Equisetum arvense (Field Horsetail) in Healthy Voluntee
  8. Klnçalp S, Ekiz F, Basar Ö, Coban S, Yüksel O. Equisetum arvense (Field Horsetail)-induced liver injury. Eur J Gastroenterol Hepatol. 2012 Feb;24(2):213-4. PubMed
  9. Ortega García JA, Angulo MG, Sobrino-Najul EJ, Soldin OP, Mira AP, Martínez-Salcedo E, Claudio L. Prenatal exposure of a girl with autism spectrum disorder to 'horsetail' (Equisetum arvense) herbal remedy and alcohol: a case report. J Med Case Rep. 2011 M PubMed
  10. Cordova E, Morganti L, Rodriguez C. Possible Drug-Herb Interaction between Herbal Supplement Containing Horsetail (Equisetum arvense) and Antiretroviral Drugs. J Int Assoc Provid AIDS Care. 2017;16(1):11-13.
  11. García Gavilán MD, Moreno García AM, Rosales Zabal JM, Navarro Jarabo JM, Sánchez Cantos A. Case of drug-induced acute pancreatitis produced by horsetail infusions. Rev Esp Enferm Dig. 2017 Apr;109(4):301-304. PubMed
  12. Vieira GT, de Oliveira TT, Carneiro MAA, et al. Antidiabetic effect of Equisetum giganteum L. extract on alloxan-diabetic rabbit. J Ethnopharmacol. 2020;260:112898. PubMed
  13. Health Canada. Organism-Equisetum arvense. Available at: http://webprod.hc-sc.gc.ca/nhpid-bdipsn/ingredReq.do?id=6117&lang=eng. Accessed 21-July 2021.
  14. Bates D, Duong TB, Kheyson S, Moore K. Hyponatremia Secondary to Decreased Oral Intake and SIADH and Possibly Exacerbated by Horsetail (Equisetum arvense). Can J Hosp Pharm 2021;74(4):386-389. PubMed

See these in context on the Horsetail monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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