Drug & supplement interaction

Dimethylglycine (dmg) + Octreotide

Octreotide brand names: Sandostatin, Mycapssa.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Dimethylglycine (dmg) and Octreotide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Octreotide states a food rule worth keeping to.

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Interaction report

Dimethylglycine (dmg) and Octreotide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Octreotide and Dimethylglycine (dmg) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Dimethylglycine (dmg) at all — not against Octreotide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dimethylglycine (dmg) safety at a glance

Dimethylglycine (d... overall Use caution Appears generally well tolerated short-term, but high-quality long-term safety data are limited.
Pregnancy Avoid Not enough safety information; best to avoid during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Octreotide and Dimethylglycine (dmg)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Octreotide’s Own FDA Label Lists

This is not an interaction — none of it involves Dimethylglycine (dmg). These are the most notable effects listed in the ADVERSE REACTIONS section of Octreotide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Loss of vision Worth acting on
  • A change in thyroid levels Worth acting on
  • Thoughts of self-harm Worth acting on
  • Hearing loss Worth acting on
  • A bowel blockage Worth acting on
  • Bleeding in the gut Worth acting on
  • Low blood sugar Worth acting on
  • A slow heartbeat Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on

Showing the 10 most notable of 44 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Octreotide. Read the label on DailyMed › Dimethylglycine (dmg)’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Dimethylglycine (dmg) side to compare — that is a limit of the record, not a statement that Dimethylglycine (dmg) has no side effects.

How to take them

Some Octreotide Products Have a Food Rule — Dimethylglycine (dmg) Should Not Break It

At least one FDA label for a product containing Octreotide says to take it on an empty stomach. Most supplements — Dimethylglycine (dmg) included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Octreotide on its own and move Dimethylglycine (dmg) to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Octreotide products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION Take MYCAPSSA orally with a glass of water on an empty stomach, at least 1 hour before a meal or at least 2 hours after a meal (‎ 2.1 ).

From the Dosage and Administration section of the FDA label we read for Octreotide — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Octreotide

This page covers Dimethylglycine (dmg) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Octreotide page lists 30 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Adrafinil (moderate), Cannabidiol (cbd) (moderate), Cannabinol (cbn) (moderate) and Cannabis (moderate).

By severity: 1 major · 19 moderate · 10 minor.

From our pharmacist’s overview on the Octreotide page

“Take this page with genuine care if you use octreotide (Sandostatin injections or Mycapssa capsules) for acromegaly or hormone-secreting tumors, since steady drug levels are what keep symptoms suppressed. Of the 30 ingredients on file, one rates major, activated charcoal, which can pull octreotide out of circulation and blunt its effec…”

Reviewed by 2 · Jul 18, 2026

Open the Octreotide interaction page

How much people look this up

Where Dimethylglycine (dmg) and Octreotide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dimethylglycine (dmg)
Steady interest

#1,299 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Octreotide
Steady interest

#2,390 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Dimethylglycine (dmg) is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dimethylglycine (dmg) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Dimethylglycine (dmg) and Octreotide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Dimethylglycine (dmg)

What is Dimethylglycine (dmg)?

  • Athletic performance and energy
  • Autism spectrum support
  • Immune support
  • Seizure disorders
  • General wellness and detox support

Dimethylglycine (DMG) is a substance made naturally in the body and found in small amounts in foods. It is marketed for energy, athletic performance, autism, and immune support, but solid human evidence for most of these uses is limited. It appears generally well tolerated in short-term use, but talk with your pharmacist or doctor before trying it.

Not applicable (a naturally occurring amino acid derivative) · Tablets, capsules, chewable tablets, sublingual tablets, powder

An interaction check asks whether these two react with each other — it does not ask whether Dimethylglycine (dmg) is a good idea for someone in your situation. Here is what our Dimethylglycine (dmg) record says about it on its own.

Dimethylglycine (dmg): dosing

There is no officially established or standardized dose of DMG. Products vary widely in strength and in the directions they give.The safest approach is to follow the dosing instructions on the product label and not exceed them. If you do not notice a clear benefit, there is no reason to keep taking it.

From our Dimethylglycine (dmg) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dimethylglycine (dmg) monograph & all interactions
Medication

About Octreotide

What Is Octreotide Used For?

Brand names: Sandostatin, Mycapssa

Octreotide injection (available as Sandostatin, BYNFEZIA Pen, and other octreotide acetate injection products) is used to lower abnormally high growth hormone and IGF-1 levels in acromegaly, and to reduce the severe diarrhea and flushing associated with metastatic carcinoid tumors and the profuse watery diarrhea caused by VIPomas (vasoactive intestinal peptide-secreting tumors).

Mycapssa, the oral delayed-release capsule, is approved specifically for long-term maintenance treatment of acromegaly in patients who have already responded to and tolerated treatment with octreotide or lanreotide injections. It is not indicated for carcinoid tumors or VIPomas.

See full Octreotide drug information
Keep checking

Other Drugs & Dimethylglycine (dmg)

Browse every other medication we’ve checked against Dimethylglycine (dmg) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Dimethylglycine (dmg) References

The 2 sources that drive our Dimethylglycine (dmg) monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Dimethylglycine (dmg) is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Dimethylglycine (dmg) and Octreotide Together: Common Questions

Is it safe to take Dimethylglycine (dmg) with Octreotide?
We do not list a known interaction between Dimethylglycine (dmg) and Octreotide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Dimethylglycine (dmg) and Octreotide at the same time of day?
At least one FDA label for a product containing Octreotide says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Octreotide on its own and move Dimethylglycine (dmg) to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Octreotide interact with any supplements?
Yes. Octreotide has documented interactions with 30 supplements in our database — Dimethylglycine (dmg) is not one of them. The Octreotide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Octreotide and Dimethylglycine (dmg)?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.