Drug & supplement interaction

Emu Oil + Mesalamine

Mesalamine brand names: Pentasa, Asacol, Canasa, Rowasa, Lialda, and others.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Emu Oil and Mesalamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Mesalamine states a food rule worth keeping to.

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Interaction report

Emu Oil and Mesalamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mesalamine and Emu Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Emu Oil at all — not against Mesalamine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Emu Oil safety at a glance

Emu Oil overall Use caution Generally well tolerated on the skin, but human evidence is limited and quality varies between products.
Pregnancy Use caution Not enough reliable safety data; topical use is likely lower risk, but check with your doctor first.
Breastfeeding Use caution Safety is not well studied, so use cautiously and avoid applying near the nipple area.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mesalamine and Emu Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Mesalamine’s Own FDA Label Lists

This is not an interaction — none of it involves Emu Oil. These are the most notable effects listed in the ADVERSE REACTIONS section of Mesalamine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • Kidney stones Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Sun sensitivity
  • Bloating or gas
  • Stomach pain
  • Diarrhea

Showing the 10 most notable of 12 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Mesalamine. Read the label on DailyMed › Emu Oil’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Emu Oil side to compare — that is a limit of the record, not a statement that Emu Oil has no side effects.

How to take them

Some Mesalamine Products Have a Food Rule — Emu Oil Should Not Break It

At least one FDA label for a product containing Mesalamine says to take it with food. If you take Emu Oil on an empty stomach out of habit, keep them separate — and take Mesalamine with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Mesalamine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2 ) Administer mesalamine delayed-release tablets with food.

From the Dosage and Administration section of the FDA label we read for Mesalamine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Overlapping uses

What Mesalamine Is Prescribed For, and What Emu Oil Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Mesalamine is a prescription medicine with approved uses on its FDA label. Emu Oil is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Mesalamine is prescribed for: Mesalamine is used to treat mildly to moderately active ulcerative colitis — a condition where the lining of the large intestine becomes inflamed and ulcerated. Depending on the product and formulation, it can be used to bring the disease under control (induction of remission) and/or to keep it from coming back (maintenance of remission). Different products target different parts of the lower digestive tract. Oral forms (tablets and capsules) treat the colon more broadly.

Read the rest of what Mesalamine is prescribed for

Rectal forms — including enemas (ROWASA, sfROWASA, mesalamine rectal suspension) — are used for distal ulcerative colitis, proctosigmoiditis, or proctitis (inflammation limited to the lower end of the colon or rectum). Rectal suppositories (CANASA, mesalamine rectal suppositories) are specifically for ulcerative proctitis (inflammation of the rectum only).

Emu Oil has been studied for:

  • Ulcerative colitis studied, not established Emu Oil has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Emu Oil for ulcerative colitis

    Although there has been interest in using oral emu oil for ulcerative colitis, there is insufficient reliable information about the clinical effects of emu oil for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Mesalamine on your own; if you are taking Emu Oil for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Emu Oil or Mesalamine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Emu Oil or Mesalamine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Mesalamine

This page covers Emu Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mesalamine page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Mesalamine page

“Activated charcoal is the one entry here I would treat as a genuine problem for anyone taking mesalamine (Asacol, Lialda, Pentasa, and others). It is the lone major-rated interaction among the 17 on file, because charcoal soaks up drugs in the gut and can pull mesalamine out of the picture before it does its job.”

Reviewed by 2 · Jul 18, 2026

Open the Mesalamine interaction page

One more smart check

Taking Emu Oil as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Emu Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Emu Oil. Even though Emu Oil itself has no known interaction with Mesalamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Emu Oil and Mesalamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Emu Oil
Steady interest

#1,353 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mesalamine
Top 25%

#687 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Emu Oil is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Emu Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Emu Oil and Mesalamine records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Emu Oil

What is Emu Oil?

  • Dry or irritated skin
  • Joint and muscle pain
  • Minor wounds and burns
  • Hair and scalp care
  • Anti-inflammatory skin support

Emu oil is a fat from the emu bird that is mostly used on the skin to moisturize and soothe irritation, and sometimes taken by mouth for inflammation. Human research is limited, so most claims are not well proven. It is generally well tolerated on the skin, but talk to your pharmacist or doctor before relying on it for any medical condition.

Fat (oil) rendered from the emu bird (Dromaius novaehollandiae) · Topical oil, creams, lotions, balms, soaps, and softgel capsules

An interaction check asks whether these two react with each other — it does not ask whether Emu Oil is a good idea for someone in your situation. Here is what our Emu Oil record says about it on its own.

Emu Oil: dosing

There is no standardized or officially established dose for emu oil. For topical products, follow the directions on the label and apply a thin layer to the affected area.For capsules taken by mouth, follow the manufacturer's instructions.

From our Emu Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Emu Oil monograph & all interactions
Medication

About Mesalamine

What Is Mesalamine Used For?

Brand names: Pentasa, Asacol, Canasa, Rowasa, Lialda, Delzicol

Mesalamine is used to treat mildly to moderately active ulcerative colitis — a condition where the lining of the large intestine becomes inflamed and ulcerated. Depending on the product and formulation, it can be used to bring the disease under control (induction of remission) and/or to keep it from coming back (maintenance of remission).

Different products target different parts of the lower digestive tract. Oral forms (tablets and capsules) treat the colon more broadly. Rectal forms — including enemas (ROWASA, sfROWASA, mesalamine rectal suspension) — are used for distal ulcerative colitis, proctosigmoiditis, or proctitis (inflammation limited to the lower end of the colon or rectum). Rectal suppositories (CANASA, mesalamine rectal suppositories) are specifically for ulcerative proctitis (inflammation of the rectum only).

See full Mesalamine drug information
Keep checking

Other Drugs & Emu Oil

Browse every other medication we’ve checked against Emu Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Emu Oil against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Emu Oil list.

See the full Emu Oil interactions page
See every supplement checked against Mesalamine, ranked by severity
Evidence & sources

Emu Oil References

The 2 sources that drive our Emu Oil monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Emu Oil is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Emu Oil and Mesalamine Together: Common Questions

Is it safe to take Emu Oil with Mesalamine?
We do not list a known interaction between Emu Oil and Mesalamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Emu Oil and Mesalamine at the same time of day?
At least one FDA label for a product containing Mesalamine says to take it with food. If you take Emu Oil on an empty stomach out of habit, keep them separate and take Mesalamine with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Mesalamine products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Are Emu Oil and Mesalamine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Emu Oil in each. That is a conversation for your prescriber, especially if Mesalamine is being adjusted to a target.
Does Mesalamine interact with any supplements?
Yes. Mesalamine has documented interactions with 17 supplements in our database — Emu Oil is not one of them. The Mesalamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Emu Oil monograph Uses, safety profile, and every drug interaction in one place Mesalamine drug information The full plain-English guide to this medication Mesalamine supplement interactions Every supplement checked against Mesalamine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mesalamine and Emu Oil?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.