Fool's Parsley + Sucralfate
Sucralfate brand names: Carafate, Antepsin.
We found no known interaction between Fool's Parsley and Sucralfate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Sucralfate states a food rule worth keeping to.
Fool's Parsley and Sucralfate
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Sucralfate and Fool's Parsley in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Fool's Parsley at all — not against Sucralfate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Fool's Parsley safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Fool's Parsley in Pregnancy & Breastfeeding
When used orally due to potential for poisoning.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Sucralfate Products Have a Food Rule — Fool's Parsley Should Not Break It
At least one FDA label for a product containing Sucralfate says to take it on an empty stomach. Most supplements — Fool's Parsley included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Sucralfate on its own and move Fool's Parsley to a meal later in the day.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Sucralfate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
D O S A G E A N D A D M INI S T R A T I O N A cti v e D u oden a l Ulc e r : The recommended adult oral dosage for duodenal ulcer is 1 g four times per day on an empty stomach.
From the Dosage and Administration section of the FDA label we read for Sucralfate — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
Questions About Fool's Parsley or Sucralfate
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Fool's Parsley or Sucralfate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Sucralfate
This page covers Fool's Parsley only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sucralfate page lists 17 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).
By severity: 1 major · 7 moderate · 9 minor.
From our pharmacist’s overview on the Sucralfate page
“If you take sucralfate (Carafate) to heal an ulcer, keep activated charcoal well away from it. Charcoal carries the sole major rating on this list because it adsorbs drugs in the digestive tract, and sucralfate works entirely there, forming a protective coating over damaged stomach lining rather than circulating through the body.”
Reviewed by 2 · Jul 18, 2026
Where Fool's Parsley and Sucralfate Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,198 of 1,452 supplements looked up here in the last 7 days
#750 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Fool's Parsley reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Fool's Parsley and Sucralfate records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Fool's Parsley
What is Fool's Parsley?
- Digestive complaints (traditional/homeopathic)
- Diarrhea in children (homeopathic tradition)
- Nausea and vomiting (homeopathic tradition)
- Restlessness (homeopathic tradition)
Fool's Parsley is a poisonous weed that closely resembles edible parsley and has no proven medicinal benefit. The raw plant is toxic and should never be eaten; the only modern use is in highly diluted homeopathic products, which lack reliable evidence of effectiveness. If you are looking for a culinary herb, do not gather wild plants that resemble parsley.
Aethusa cynapium · Apiaceae · Whole plant (aerial parts), occasionally used in homeopathic preparations · Homeopathic dilutions; rarely as crude plant material (not recommended)
An interaction check asks whether these two react with each other — it does not ask whether Fool's Parsley is a good idea for someone in your situation. Here is what our Fool's Parsley record says about it on its own.
Fool's Parsley: dosing
There is no established safe medicinal dose of Fool's Parsley. The crude plant is poisonous and should not be taken at any amount.For homeopathic products, dosing follows the directions on the specific product label, but these are not standardized medical doses and are not supported by strong evidence.
From our Fool's Parsley monograph — the full record covers uses, side effects and every documented interaction.
About Sucralfate
What Is Sucralfate Used For?
Brand names: Carafate, Antepsin
Sucralfate — available as tablets and oral suspension under brand names including Carafate — is used for the short-term treatment (up to 8 weeks) of active duodenal ulcers.
Carafate tablets and sucralfate tablets are also approved for maintenance therapy — meaning a lower dose taken after an ulcer heals to help keep it from coming back.
Most-Reported Side Effects for Sucralfate
From FAERS, the FDA’s public side-effect reporting system (23,819 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Fool's Parsley
Browse every other medication we’ve checked against Fool's Parsley — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Fool's Parsley against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Fool's Parsley list.
Fool's Parsley References
The 1 references that drive our Fool's Parsley monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Sucralfate Is Linked to Lower Levels of One Nutrient
Natural Medicines records Sucralfate as a medicine that can lower these. This is not an interaction with Fool's Parsley — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Sucralfate nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Fool's Parsley and Sucralfate Together: Common Questions
Is it safe to take Fool's Parsley with Sucralfate?
Should I take Fool's Parsley and Sucralfate at the same time of day?
Does Sucralfate interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Sucralfate and Fool's Parsley?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.