Foxglove - Nuzyra (Omadacycline (IV)) Interaction
Herbal: Foxglove
Drug: Omadacycline (IV)
Brand names:
Nuzyra

Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 18, 2025
Interaction Details
Omadacycline (IV) is classified as belonging to the following category: Tetracycline Antibiotics
Theoretically, concomitant use of quinine increases the risk of cardiac glycoside toxicity.
Foxglove contains varied cardiac glycosides, including digoxin. Tetracycline can increase oral absorption of some cardiac glycosides.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
Omadacycline (IV) Overview
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Omadacycline injection is used to treat infections caused by bacteria, including pneumonia and certain infections of the skin. Omadacycline injection is in a class of medications called tetracycline antibiotics. It works by preventing the growth and spread of bacteria.
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Antibiotics such as omadacycline will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Foxglove - More Interactions
Foxglove interacts with 133 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
Unknown | No interactions have been reported or no interaction data is currently available. |
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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Drug descriptions are provided by MedlinePlus.