Gras + Methylene Blue
Methylene Blue brand names: Urolene Blue, Provayblue.
We found no known interaction between Gras and Methylene Blue in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Gras and Methylene Blue
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Methylene Blue and Gras in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Gras at all — not against Methylene Blue, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Gras safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Methylene Blue
This page covers Gras only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Methylene Blue page lists 38 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Lithium (major), 5-htp (moderate), Acetyl-l-carnitine (moderate) and Ayahuasca (moderate).
By severity: 2 major · 25 moderate · 11 minor.
From our pharmacist’s overview on the Methylene Blue page
“The pairing I would worry about first with methylene blue (Urolene Blue, Provayblue) is anything that raises serotonin, and lithium heads that group with a major rating. Methylene blue inhibits monoamine oxidase A, the enzyme that breaks serotonin down, so combining it with serotonin-boosting supplements can tip someone into serotonin…”
Reviewed by 2 · Jul 18, 2026
Where Gras and Methylene Blue Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#946 of 1,452 supplements looked up here in the last 7 days
#53 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Gras is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Gras reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Gras and Methylene Blue records this page draws on were last updated June 20, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Gras
What is Gras?
We could not find reliable information about a dietary supplement or herb called "Gras." The name may be a misspelling, a brand name, or a local/regional term, so we cannot confirm what it is, what it does, or whether it is safe. Please double-check the name with your pharmacist or the product label before using it.
An interaction check asks whether these two react with each other — it does not ask whether Gras is a good idea for someone in your situation. Here is what our Gras record says about it on its own.
Gras: dosing
There is no established or recommended dose for "Gras" because the product cannot be reliably identified. We will not guess an amount. If you have a labeled product, follow the manufacturer's instructions only after confirming the actual ingredient with a pharmacist or doctor.
From our Gras monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & Gras
Browse every other medication we’ve checked against Gras — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Gras against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Gras list.
Gras References
The 3 sources that drive our Gras monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Gras is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Dietary and Herbal Supplements — NIH NCCIH Source
- Herbs and Supplements — MedlinePlus Source
- Generally Recognized as Safe (GRAS) — U.S. Food and Drug Administration Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Gras and Methylene Blue Together: Common Questions
Is it safe to take Gras with Methylene Blue?
Does Methylene Blue interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.