Greek Sage + Naltrexone Hydrochloride, Oxycodone Hydrochloride
Naltrexone Hydrochloride, Oxycodone Hydrochloride brand name: Troxyca ER.
We found no known interaction between Greek Sage and Naltrexone Hydrochloride, Oxycodone Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Greek Sage and Naltrexone Hydrochloride, Oxycodone Hydrochloride
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Naltrexone Hydrochloride, Oxycodone Hydrochloride and Greek Sage in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Greek Sage safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Naltrexone Hydrochloride, Oxycodone Hydrochloride
Interactions in our licensed database are recorded against drug classes, not just single drug names. Naltrexone Hydrochloride, Oxycodone Hydrochloride is filed under 7 classifications — including narcotic drugs, cytochrome p450 2d6 (cyp2d6) substrates, cns depressants. Greek Sage has documented interactions with 1 drug class — the most serious being hexobarbital (moderate) — and none of Naltrexone Hydrochloride, Oxycodone Hydrochloride’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Greek Sage Does Interact With Other Medications
Greek Sage has 1 moderate known drug interaction in our database — Naltrexone Hydrochloride, Oxycodone Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Greek Sage
We haven’t checked that one against Greek Sage yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Greek Sage. Pick one to open its full report.
See Every Supplement That Interacts With Naltrexone Hydrochloride, Oxycodone Hydrochloride
This page covers Greek Sage only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naltrexone Hydrochloride, Oxycodone Hydrochloride page lists 145 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).
By severity: 8 major · 114 moderate · 23 minor.
From our pharmacist’s overview on the Naltrexone Hydrochloride, Oxycodone Hydrochloride page
“Alcohol tops this list. Beer and wine both carry major, well-documented interactions with Troxyca ER (naltrexone and oxycodone hydrochloride), an extended-release opioid, because adding a second sedative to an opioid can slow breathing, not just deepen drowsiness.”
Reviewed by 2 · Jul 18, 2026
Open the Naltrexone Hydrochloride, Oxycodone Hydrochloride interaction page
Where Greek Sage and Naltrexone Hydrochloride, Oxycodone Hydrochloride Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#890 of 1,452 supplements looked up here in the last 7 days
#444 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Greek Sage reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Greek Sage and Naltrexone Hydrochloride, Oxycodone Hydrochloride records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Greek Sage
What is Greek Sage?
- Sore throat and mouth irritation
- Digestive upset
- Memory and cognition support
- Antimicrobial purposes
- Flavoring and aromatherapy
Greek sage (Salvia fruticosa) is a Mediterranean herb traditionally used as a tea and flavoring, and popularly for sore throats and digestion. Solid human research on its health benefits is limited, so most uses are based on tradition or early lab studies. It is generally considered safe in food amounts, but talk to a pharmacist or doctor before using concentrated extracts or essential oils.
Salvia fruticosa · Lamiaceae · Leaves and essential oil · Tea, dried leaf, capsules, essential oil, extracts
An interaction check asks whether these two react with each other — it does not ask whether Greek Sage is a good idea for someone in your situation. Here is what our Greek Sage record says about it on its own.
Greek Sage: dosing
There is no official standardized dose of Greek sage. Traditional use is usually a cup of tea made from a small amount of dried leaf.For capsules, extracts, or essential oil products, follow the directions on the label, since the strength varies a lot between products.
From our Greek Sage monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & Greek Sage
Browse every other medication we’ve checked against Greek Sage — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
No interaction 2,828 drugs checked — show the list
We also checked Greek Sage against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Ivermectin ›
- Aspirin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Tadalafil ›
- Clopidogrel ›
- Atorvastatin ›
- Abemaciclib ›
- Docusate ›
- Hydroxyurea ›
- Valacyclovir ›
- Ibuprofen ›
- Methamphetamine ›
- Semaglutide ›
- Sumatriptan ›
- Warfarin Sodium ›
- Tirzepatide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Acyclovir ›
- Amitriptyline ›
- Methotrexate ›
- Doxycycline ›
- Fluoxetine ›
- Acetaminophen, Codeine ›
- Lamotrigine ›
- Amphetamine ›
- Pregabalin ›
- Gabapentin ›
- Dextroamphetamine ›
- Azithromycin ›
- Isotretinoin ›
- Methylene Blue ›
- Clonazepam ›
- Omeprazole ›
- Amlodipine Besylate ›
- Quetiapine ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Naproxen ›
- Citalopram ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Greek Sage list.
Greek Sage References
The 1 references that drive our Greek Sage monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Todorov S, Philianos S, Petkov V, et al. Experimental pharmacological study of three species from genus Salvia. Acta Physiol Pharmacol (Bulg) 1984;10:13-20.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Greek Sage and Naltrexone Hydrochloride, Oxycodone Hydrochloride Together: Common Questions
Is it safe to take Greek Sage with Naltrexone Hydrochloride, Oxycodone Hydrochloride?
How was the Greek Sage and Naltrexone Hydrochloride, Oxycodone Hydrochloride combination checked?
Does Greek Sage interact with any other medications?
Does Naltrexone Hydrochloride, Oxycodone Hydrochloride interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Naltrexone Hydrochloride, Oxycodone Hydrochloride and Greek Sage?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.