Drug & supplement interaction

Guided Imagery + Tofacitinib

Tofacitinib brand names: Xeljanz, Xeljanz XR.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Guided Imagery and Tofacitinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Guided Imagery and Tofacitinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tofacitinib and Guided Imagery in our sources. This does not guarantee that the combination is completely free of risk — research on Guided Imagery alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Guided Imagery at all — not against Tofacitinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Guided Imagery is a practice rather than something you take. Ask your care team whether the type and intensity you plan to practice are appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Guided Imagery safety at a glance

Guided Imagery overall Generally safe It is a non-drug relaxation practice and is very low risk for most people.
Pregnancy Generally safe Generally considered safe and is sometimes used for relaxation and childbirth preparation.
Breastfeeding Generally safe No physical exposure to the baby; considered safe while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tofacitinib and Guided Imagery? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Tofacitinib’s Own FDA Label Lists

This is not an interaction — none of it involves Guided Imagery. These are the most notable effects listed in the ADVERSE REACTIONS section of Tofacitinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you practice Guided Imagery and take the medicine. 6 of them are worth acting on rather than waiting out — marked below.

  • Low blood sugar Worth acting on
  • Blood clots Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Joint pain mentioned in 29.0% of FDA reports for Tofacitinib
  • Headache mentioned in 7.3% of FDA reports for Tofacitinib
  • Diarrhea
  • A skin rash

From the ADVERSE REACTIONS section of the FDA label for Tofacitinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 185,980 voluntary FDA FAERS reports for Tofacitinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Guided Imagery’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Guided Imagery side to compare — that is a limit of the record, not a statement that Guided Imagery has no side effects.

Overlapping uses

What Tofacitinib Is Prescribed For, and What Guided Imagery Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Tofacitinib is a prescription medicine with approved uses on its FDA label. Guided Imagery is a practice: what follows is what researchers have looked at it for, and how strong that evidence is.

Guided Imagery has been studied for:

  • Juvenile idiopathic arthritis studied, not established Guided Imagery has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Guided Imagery for juvenile idiopathic arthritis

    Although there has been interest in using guided imagery for JIA, there is insufficient reliable information about the clinical effects of guided imagery for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Tofacitinib on your own; if you are taking Guided Imagery for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Tofacitinib

This page covers Guided Imagery only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tofacitinib page lists 184 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Active Hexose Correlated Compound (ahcc) (moderate).

By severity: 3 major · 143 moderate · 38 minor.

From our pharmacist’s overview on the Tofacitinib page

“Supplements deserve genuine care alongside tofacitinib (Xeljanz, Xeljanz XR), a medicine that deliberately dials down the immune system to control conditions like rheumatoid arthritis and ulcerative colitis. Most of the interactions on this page run through the liver enzymes that clear the drug, meaning an herb can push its blood level…”

Reviewed by 2 · Jul 18, 2026

Open the Tofacitinib interaction page

How much people look this up

Where Guided Imagery and Tofacitinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Guided Imagery
Steady interest

#1,116 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tofacitinib
Steady interest

#1,579 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Guided Imagery is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Guided Imagery reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Guided Imagery and Tofacitinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Mind-body practice

About Guided Imagery

What is Guided Imagery?

  • Stress and anxiety
  • Pain management
  • Sleep problems
  • Coping with cancer treatment
  • Preparing for or recovering from surgery
  • Relaxation

Guided imagery is a mind-body relaxation technique in which you use your imagination and the senses to picture calming images, often led by a recording or a trained practitioner. It is generally very safe and may help with stress, anxiety, pain, and sleep, though it works best as a complement to—not a replacement for—standard medical care. It is not a pill or herb, so there is little risk of physical harm for most people.

Not applicable (mind-body technique) · Audio recordings, scripts read by a therapist, apps, in-person sessions, group classes

An interaction check asks whether these two react with each other — it does not ask whether Guided Imagery is a good idea for someone in your situation. Here is what our Guided Imagery record says about it on its own.

Guided Imagery: dosing

There is no standard "dose" for guided imagery because it is a mind-body practice, not a supplement. Sessions commonly last anywhere from a few minutes to about 20–30 minutes, and people may practice once a day or as needed.If you are using a recording, app, or program, follow the instructions provided. Practicing regularly tends to help people get more comfortable and may improve the benefits over time. A pharmacist, doctor, or mental health professional can help you choose a reputable program and fit it into your care plan.

From our Guided Imagery monograph — the full record covers uses, side effects and every documented interaction.

Read the full Guided Imagery monograph & all interactions
Medication

About Tofacitinib

What Is Tofacitinib Used For?

Brand names: Xeljanz, Xeljanz XR

  • Tofacitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who are unable to take or did not respond to one or more tumor necrosis factor (TNF) inhibitor medication(s). It is also used to treat psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin) in adults who are unable to take or did not respond to or tolerate one or more TNF inhibitor medication(s). Tofacitinib is used to treat ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) in adults who are unable to take or who did not respond to one or more TNF inhibitor medication(s). It is also used to treat polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children 2 years and older who are unable to take or who did not respond to one or more TNF inhibitor medication(s). Tofacitinib is in a class of medications called Janus kinase (JAK) inhibitors. It works by decreasing the activity of the immune system.

See full Tofacitinib drug information
Keep checking

Other Drugs & Guided Imagery

Browse every other medication we’ve checked against Guided Imagery — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Guided Imagery References

The 1 sources that drive our Guided Imagery monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Guided Imagery is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Relaxation Techniques: What You Need To Know — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Practicing Guided Imagery While Taking Tofacitinib: Common Questions

Is it safe to practice Guided Imagery while taking Tofacitinib?
We do not list a known interaction between Guided Imagery and Tofacitinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Guided Imagery and Tofacitinib used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Guided Imagery in each. That is a conversation for your prescriber, especially if Tofacitinib is being adjusted to a target.
Does Tofacitinib interact with any supplements?
Yes. Tofacitinib has documented interactions with 184 supplements in our database — Guided Imagery is not one of them. The Tofacitinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tofacitinib and Guided Imagery?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.