Drug & supplement interaction

Gumweed + Oxandrolone

Oxandrolone brand names: Oxandrin, Anavar.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Gumweed and Oxandrolone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Gumweed and Oxandrolone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Oxandrolone and Gumweed in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Gumweed at all — not against Oxandrolone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Gumweed safety at a glance

Gumweed overall Use caution Generally used in small amounts traditionally, but human safety data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Oxandrolone and Gumweed? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Gumweed Itself Has Been Linked To

This is not an interaction — nothing below involves Oxandrolone. It is the side-effect record for Gumweed on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Gumweed, this list is the first place to look.

  • Diarrhea Additional detail

    “Orally, gumweed seems to be well tolerated. It can cause gastric mucosal irritation (2,12), diarrhea (18), and kidney irritation (12).”

    Gumweed · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
    3. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, gumweed can cause gastric mucosal irritation (2,12) and diarrhea (18).”

    Gumweed · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
    3. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Gumweed — expand a row for the licensed statement it rests on. We haven’t matched Oxandrolone to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Oxandrolone.

Everything else you take

See Every Supplement That Interacts With Oxandrolone

This page covers Gumweed only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Oxandrolone page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Oxandrolone page

“Every supplement known to interact with oxandrolone (Oxandrin, Anavar) works the same basic way: it can change how much of the tablet actually reaches your bloodstream. Oxandrolone is an anabolic steroid prescribed to rebuild weight and muscle after surgery, severe illness, or long-term wasting, so a dose that under-absorbs means the r…”

Reviewed by 2 · Jul 18, 2026

Open the Oxandrolone interaction page

One more smart check

Taking Gumweed as Part of a Dietary Supplement Product? Check It for Interactions

We hold 18 real supplement products containing Gumweed, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Gumweed. Even though Gumweed itself has no known interaction with Oxandrolone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Gumweed and Oxandrolone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Gumweed
Steady interest

#976 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Oxandrolone
Steady interest

#2,393 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Gumweed reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Gumweed and Oxandrolone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Gumweed

What is Gumweed?

  • Cough and bronchitis
  • Asthma-related breathing problems
  • Skin irritation from poison ivy or poison oak
  • Minor wounds and rashes
  • Upper respiratory congestion

Gumweed is a traditional North American plant used mostly for coughs, chest congestion, and skin irritation such as poison ivy rashes. Good-quality human studies are lacking, so its benefits are not well proven, and it should be used cautiously and avoided during pregnancy and breastfeeding.

Grindelia robusta · Asteraceae · Dried leaves and flowering tops · Tea, tincture, liquid extract, capsules, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Gumweed is a good idea for someone in your situation. Here is what our Gumweed record says about it on its own.

Gumweed: dosing

There is no well-established, standardized dose for gumweed. Traditional preparations include teas, tinctures, and liquid extracts, but the strength of commercial products varies widely.The safest approach is to follow the directions on the product label and not exceed the suggested amount.

From our Gumweed monograph — the full record covers uses, side effects and every documented interaction.

Read the full Gumweed monograph & all interactions
Medication

About Oxandrolone

What Is Oxandrolone Used For?

Brand names: Oxandrin, Anavar

  • Oxandrolone is used with a diet program to cause weight gain in people who have lost too much weight due to surgery, injury, chronic (long-lasting) infections, trauma, or who are underweight for unknown reasons. Oxandrolone is also used to treat bone pain in people with osteoporosis (a condition in which the bones become thin and weak and break easily) and to prevent certain side effects in people who take corticosteroids (a group of medications used to treat many conditions that involve inflammation or swelling of part of the body) for a long time. Oxandrolone is in a class of medications called androgenic hormones. It works by increasing the amount of protein made by the body. This protein is used to build more muscle and increase body weight.

See full Oxandrolone drug information
Keep checking

Other Drugs & Gumweed

Browse every other medication we’ve checked against Gumweed — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Gumweed References

The 3 references that drive our Gumweed monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Gumweed and Oxandrolone Together: Common Questions

Is it safe to take Gumweed with Oxandrolone?
We do not list a known interaction between Gumweed and Oxandrolone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Oxandrolone interact with any supplements?
Yes. Oxandrolone has documented interactions with 17 supplements in our database — Gumweed is not one of them. The Oxandrolone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Oxandrolone and Gumweed?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.