Drug & supplement interaction

Hartstongue + Digoxin

Digoxin brand names: Lanoxicaps, Lanoxin, Digitek.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Hartstongue and Digoxin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Hartstongue and Digoxin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Digoxin and Hartstongue in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Hartstongue at all — not against Digoxin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Hartstongue safety at a glance

Hartstongue overall Not established Modern safety data are very limited, so caution is advised.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid it to be safe.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Digoxin and Hartstongue? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Digoxin’s Own FDA Label Lists

This is not an interaction — none of it involves Hartstongue. These are the most notable effects listed in the ADVERSE REACTIONS section of Digoxin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • A slow heartbeat Worth acting on
  • Hallucinations Worth acting on
  • Heart failure Worth acting on
  • An irregular heartbeat Worth acting on
  • Confusion Worth acting on
  • Low mood Worth acting on
  • A low platelet count Worth acting on
  • Breast tenderness
  • Blurred vision
  • A fast or pounding heartbeat

Showing the 10 most notable of 20 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Digoxin. Read the label on DailyMed › Hartstongue’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Hartstongue side to compare — that is a limit of the record, not a statement that Hartstongue has no side effects.

From our Q&A

Questions About Hartstongue or Digoxin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Hartstongue or Digoxin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Digoxin

This page covers Hartstongue only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Digoxin page lists 113 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Aloe (major), Blue Flag (major), Danshen (major) and European Buckthorn (major).

By severity: 18 major · 79 moderate · 16 minor.

From our pharmacist’s overview on the Digoxin page

“Digoxin is a heart medicine with a narrow therapeutic index, meaning the gap between a helpful blood level and a harmful one is small, and few drugs give me more pause when supplements enter the picture. The most serious entries here are herbs that themselves contain digoxin-like cardiac glycosides, foxglove and lily-of-the-valley amon…”

Reviewed by 2 · Jul 18, 2026

Open the Digoxin interaction page

One more smart check

Taking Hartstongue as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Hartstongue, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Hartstongue. Even though Hartstongue itself has no known interaction with Digoxin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Hartstongue and Digoxin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Hartstongue
Steady interest

#1,452 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Digoxin
Top 25%

#379 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Hartstongue is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hartstongue reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Hartstongue and Digoxin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Hartstongue

What is Hartstongue?

  • Cough and chest congestion
  • Digestive complaints
  • Liver and spleen support (traditional)
  • Mild diarrhea
  • Wound healing (topical, traditional)

Hartstongue is a fern that has been used in traditional European herbal medicine, mainly for coughs and digestive complaints. There is very little modern scientific research to confirm that it works for any health condition, so its effectiveness is largely unproven. If you are considering it, talk with a pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Asplenium scolopendrium · Aspleniaceae · Leaves (fronds) · Dried herb, tea/infusion, tincture

An interaction check asks whether these two react with each other — it does not ask whether Hartstongue is a good idea for someone in your situation. Here is what our Hartstongue record says about it on its own.

Hartstongue: dosing

There is no established, scientifically supported dose for Hartstongue. Traditional use involved brewing the dried fronds as a tea, but standardized amounts have not been set through modern research.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Hartstongue monograph — the full record covers uses, side effects and every documented interaction.

Read the full Hartstongue monograph & all interactions
Medication

About Digoxin

What Is Digoxin Used For?

Brand names: Lanoxicaps, Lanoxin, Digitek

Digoxin treats mild to moderate heart failure in adults. It improves heart failure symptoms and exercise capacity, and it reduces heart failure-related hospitalizations and emergency care. It does not change survival.

It also helps control the resting heart rate in adults with chronic atrial fibrillation (an irregular heartbeat). In children with heart failure, the tablet, oral solution and most injection products are used to increase the heart’s pumping strength (myocardial contractility). Some older injection labels list only the adult uses. Digoxin Oral Solution should not be used for multifocal atrial tachycardia.

See full Digoxin drug information
Keep checking

Other Drugs & Hartstongue

Browse every other medication we’ve checked against Hartstongue — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Hartstongue References

The 2 sources that drive our Hartstongue monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Hartstongue is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Hartstongue and Digoxin Together: Common Questions

Is it safe to take Hartstongue with Digoxin?
We do not list a known interaction between Hartstongue and Digoxin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Digoxin interact with any supplements?
Yes. Digoxin has documented interactions with 113 supplements in our database — Hartstongue is not one of them. The Digoxin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Digoxin and Hartstongue?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.