Hartstongue + Lesinurad
Lesinurad brand name: Zurampic.
We found no known interaction between Hartstongue and Lesinurad in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Hartstongue and Lesinurad
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Lesinurad and Hartstongue in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Hartstongue at all — not against Lesinurad, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Hartstongue safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Lesinurad
This page covers Hartstongue only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lesinurad page lists 97 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Adrafinil (moderate), African Wild Potato (moderate), Alkanna (moderate) and Alpine Ragwort (moderate).
By severity: 1 major · 74 moderate · 22 minor.
From our pharmacist’s overview on the Lesinurad page
“Activated charcoal is the one major-rated entry among the 97 supplements and herbs on file for lesinurad (Zurampic), and it undermines the drug directly. Charcoal binds medicines in the gut and can cut how much lesinurad you absorb, letting uric acid climb and gout flare.”
Reviewed by 2 · Jul 18, 2026
Taking Hartstongue as Part of a Dietary Supplement Product? Check It for Interactions
We hold 2 real supplement products containing Hartstongue, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Hartstongue. Even though Hartstongue itself has no known interaction with Lesinurad, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Hartstongue and Lesinurad Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,315 of 1,452 supplements looked up here in the last 7 days
#1,723 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Hartstongue is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hartstongue reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Hartstongue and Lesinurad records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Hartstongue
What is Hartstongue?
- Cough and chest congestion
- Digestive complaints
- Liver and spleen support (traditional)
- Mild diarrhea
- Wound healing (topical, traditional)
Hartstongue is a fern that has been used in traditional European herbal medicine, mainly for coughs and digestive complaints. There is very little modern scientific research to confirm that it works for any health condition, so its effectiveness is largely unproven. If you are considering it, talk with a pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.
Asplenium scolopendrium · Aspleniaceae · Leaves (fronds) · Dried herb, tea/infusion, tincture
An interaction check asks whether these two react with each other — it does not ask whether Hartstongue is a good idea for someone in your situation. Here is what our Hartstongue record says about it on its own.
Hartstongue: dosing
There is no established, scientifically supported dose for Hartstongue. Traditional use involved brewing the dried fronds as a tea, but standardized amounts have not been set through modern research.If you choose to use a commercial product, follow the directions on the label and do not exceed them.
From our Hartstongue monograph — the full record covers uses, side effects and every documented interaction.
About Lesinurad
What Is Lesinurad Used For?
Brand name: Zurampic
-
Lesinurad is used in combination with a xanthine oxidase inhibitor to treat hyperuricemia (high levels of uric acid) in people with gout (sudden attacks of redness, swelling, pain, and heat in one or more joints) whose disease is not controlled with their current medication. Lesinurad is in a class of medications called selective uric acid reabsorption inhibitors. It works by helping the kidneys to remove uric acid from the body.
Other Drugs & Hartstongue
Browse every other medication we’ve checked against Hartstongue — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Hartstongue against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Clopidogrel ›
- Escitalopram ›
- Rivaroxaban ›
- Atorvastatin ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Warfarin Sodium ›
- Tadalafil ›
- Sumatriptan ›
- Valacyclovir ›
- Hydroxyurea ›
- Semaglutide ›
- Prednisone ›
- Amitriptyline ›
- Propranolol ›
- Metformin ›
- Lisdexamfetamine ›
- Isotretinoin ›
- Amoxicillin ›
- Methotrexate ›
- Lisinopril ›
- Amlodipine Besylate ›
- Amphetamine ›
- Bendamustine ›
- Bupropion ›
- Fluoxetine ›
- Doxycycline ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Codeine ›
- Naproxen ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Duloxetine ›
- Methylene Blue ›
- Letrozole ›
- Citalopram ›
- Buspirone ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Hartstongue list.
Hartstongue References
The 2 sources that drive our Hartstongue monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Hartstongue is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Hartstongue and Lesinurad Together: Common Questions
Is it safe to take Hartstongue with Lesinurad?
Does Lesinurad interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Lesinurad and Hartstongue?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.