Hedge-hyssop + Sulfacetamide
Sulfacetamide brand name: AK-Sulf.
We found no known interaction between Hedge-hyssop and Sulfacetamide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Hedge-hyssop and Sulfacetamide
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Sulfacetamide and Hedge-hyssop in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Hedge-hyssop at all — not against Sulfacetamide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Hedge-hyssop safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Hedge-hyssop in Pregnancy & Breastfeeding
When used orally due to toxic potential.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Sulfacetamide
This page covers Hedge-hyssop only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sulfacetamide page lists 20 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Alfalfa (moderate), Angelica Archangelica (moderate), Arrach (moderate), Bergamot (moderate) and Bishop's Weed (moderate).
By severity: 19 moderate · 1 minor.
From our pharmacist’s overview on the Sulfacetamide page
“Every one of the 20 supplement interactions on file for sulfacetamide (AK-Sulf), a sulfa antibiotic used in eye drops and skin preparations, comes down to the same issue, added sun sensitivity. Sulfa drugs can make skin react more strongly to sunlight, and each ingredient below, St.”
Reviewed by 2 · Jul 18, 2026
Where Hedge-hyssop and Sulfacetamide Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,344 of 1,452 supplements looked up here in the last 7 days
#1,876 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hedge-hyssop reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Hedge-hyssop and Sulfacetamide records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Hedge-hyssop
What is Hedge-hyssop?
- Constipation and as a laxative
- Fluid retention (diuretic use)
- Liver and digestive complaints
- Skin conditions (traditional/topical)
- Inducing vomiting (historical purgative)
Hedge-hyssop is a traditional European herb that was historically used as a strong laxative, diuretic, and purgative, but it is considered toxic and is not recommended for self-treatment. There is no reliable modern evidence that it is safe or effective, and serious poisoning has been reported, so it is best avoided.
Gratiola officinalis · Plantaginaceae · Aerial parts (leaves and flowering stems), sometimes the root · Dried herb, tincture, and historically homeopathic preparations
An interaction check asks whether these two react with each other — it does not ask whether Hedge-hyssop is a good idea for someone in your situation. Here is what our Hedge-hyssop record says about it on its own.
Hedge-hyssop: dosing
There is no established safe or standardized dose of hedge-hyssop. Because the plant is toxic and the margin between a traditional dose and a harmful dose is narrow, no specific amount can be recommended.We do not advise self-treating with this herb.
From our Hedge-hyssop monograph — the full record covers uses, side effects and every documented interaction.
About Sulfacetamide Ophthalmic
What Is Sulfacetamide Ophthalmic Used For?
Brand name: AK-Sulf
Sulfacetamide Sodium Ophthalmic Solution USP, 10% is used to treat conjunctivitis (pink eye) and other superficial infections on the surface of the eye caused by susceptible bacteria. These include bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella species, and others.
It is also used alongside systemic (oral or injectable) sulfonamide antibiotic therapy in the treatment of trachoma, a serious bacterial eye infection. It is important to note that this medication does not work against all types of bacteria — it does not provide adequate coverage against Neisseria species, Serratia marcescens, or Pseudomonas aeruginosa, and some staph bacteria are fully resistant to it.
Most-Reported Side Effects for Sulfacetamide
From FAERS, the FDA’s public side-effect reporting system (736 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Hedge-hyssop
Browse every other medication we’ve checked against Hedge-hyssop — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Hedge-hyssop against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Losartan Potassium ›
- Aspirin ›
- Abemaciclib ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Hedge-hyssop list.
Hedge-hyssop References
The 1 references that drive our Hedge-hyssop monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Hedge-hyssop and Sulfacetamide Together: Common Questions
Is it safe to take Hedge-hyssop with Sulfacetamide?
Does Sulfacetamide interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.