Medication interaction hub

What Supplements Interact with Sulfacetamide?

Sulfacetamide brand name: AK-Sulf. Every interaction below applies to the brands too.

20 Interactions 19 Moderate 1 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Sulfacetamide? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Sulfacetamide against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Every one of the 20 supplement interactions on file for sulfacetamide (AK-Sulf), a sulfa antibiotic used in eye drops and skin preparations, comes down to the same issue, added sun sensitivity. Sulfa drugs can make skin react more strongly to sunlight, and each ingredient below, St. John's wort and chlorophyll among the more familiar, carries its own photosensitizing potential, so combining them can stack the effect. None rates major; 19 are moderate and one minor, so this sits in watchful-but-workable territory rather than alarming.

Watching means literally that. While using any of these products with sulfacetamide, notice whether your skin burns faster than usual or a rash appears on sun-exposed areas, and cover up outdoors. One entry is not a supplement at all; light therapy stacks the same risk and should be avoided during treatment. For everything else, sensible sun habits do most of the protective work.

— , Clinical Pharmacist · July 18, 2026

Moderate 19 Minor 1 No known interaction 1,432

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Sulfacetamide: Top Interactions at a Glance

The most significant Sulfacetamide supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 20 interacting ingredients — plus 1,432 more checked with no known interaction. See the complete ranked list.

Start here

The Moderate Interactions to Know About

The most clinically significant Sulfacetamide + supplement combinations in our database, best-documented first. Open any card for the full report.

Moderate Likelihood Probable Bergamot + Sulfacetamidei

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.

Read the full interaction Moderate Likelihood Probable Chenopodium Oil + Sulfacetamidei

Theoretically, concomitant use of chenopodium oil with other photosensitizing drugs can increase the risk of adverse effects.

Read the full interaction Moderate Likelihood Probable Chlorophyll + Sulfacetamidei

Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.

Read the full interaction Moderate Likelihood Probable Chlorophyllin + Sulfacetamidei

Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.

Read the full interaction Moderate Likelihood Probable Masterwort + Sulfacetamidei

The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effects.

Read the full interaction Moderate Likelihood Probable Wild Carrot + Sulfacetamidei

Theoretically, concomitant use might result in increased photosensitivity.

Read the full interaction
The complete list

Every Supplement Checked Against Sulfacetamide

All 1,452 ingredients in our database, ranked by severity — 20 with a Sulfacetamide interaction on file and 1,432 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Sulfacetamide?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Chlorophyll with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.

Full Chlorophyll + Sulfacetamide answer

Can you take Alfalfa with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Full Alfalfa + Sulfacetamide answer

Can you take Bergamot with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.

Full Bergamot + Sulfacetamide answer

Can you take Chenopodium Oil with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chenopodium oil with other photosensitizing drugs can increase the risk of adverse effects.

Full Chenopodium Oil + Sulfacetamide answer

Can you take Chlorophyllin with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.

Full Chlorophyllin + Sulfacetamide answer

Can you take Masterwort with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effec...

Full Masterwort + Sulfacetamide answer

Can you take Wild Carrot with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Wild Carrot + Sulfacetamide answer

Can you take Angelica Archangelica with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Angelica archangelica, whether ingested or applied to the skin, has the potential to induce photosensitivity reactions.

Full Angelica Archangelica + Sulfacetamide answer

Can you take Arrach with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of arrach can increase risk of adverse effects, as unspecified Chenopodium species are associated with photos...

Full Arrach + Sulfacetamide answer

Can you take Bishop's Weed with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bishop's weed constituents seem to cause photosensitivity.

Full Bishop's Weed + Sulfacetamide answer

Can you take Chlorella with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chlorella might have additive effects with photosensitizing drugs.

Full Chlorella + Sulfacetamide answer

Can you take Cilantro with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that coriandrin, a constituent of cilantro, has photosensitizing effects.

Full Cilantro + Sulfacetamide answer

Can you take Coriander with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.

Full Coriander + Sulfacetamide answer

Can you take Fig with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fig might increase the risk of photosensitivity when used in combination with photosensitizing drugs.

Full Fig + Sulfacetamide answer

Can you take Khella with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Khella + Sulfacetamide answer

Can you take Light Therapy with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Light therapy may increase the risk for photosensitization.

Full Light Therapy + Sulfacetamide answer

Can you take Lime with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.

Full Lime + Sulfacetamide answer

Can you take Rue with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rue might increase the risk for phototoxicity when used with photosensitizing drugs.

Full Rue + Sulfacetamide answer

Can you take St. John's Wort with Sulfacetamide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, St.

Full St. John's Wort + Sulfacetamide answer

Can you take Celery with Sulfacetamide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.

Full Celery + Sulfacetamide answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Sulfacetamide is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Sulfacetamide, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Sulfacetamide sits in 1 interaction category. Open any one to see what the group means:

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Sulfacetamide through this category.

About Sulfacetamide

Sulfacetamide ophthalmic is an antibiotic eye treatment used to treat conjunctivitis and other superficial eye infections, and as a support therapy for trachoma.

Generic name: Sulfacetamide  ·  Brand name: AK-Sulf.

See the full Sulfacetamide Ophthalmic drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Sulfacetamide

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Sulfacetamide.

Search a supplement product

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Products that contain Sulfacetamide-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Sulfacetamide.

Citrus Bergamot Extract 2000 mg by tnvitamins contains Bergamot Bergamot 500 mg by Solaray contains Bergamot Bergamot 375 by ProCaps contains Bergamot Resveratrol Berberine Quercetin Apple Cider Vinegar Acai & Noni by Nutra Harmony contains Bergamot BCT Herbal Oil by Professional Botanicals contains Chenopodium Oil
Pharmacist Counseling Corner

Sulfacetamide & Supplements: Common Questions

What supplements interact with Sulfacetamide?
In our interaction database, 20 supplement and herbal ingredients have an interaction with Sulfacetamide on file — 0 rated major, 19 moderate, and 1 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Bergamot, Chenopodium Oil, Chlorophyll.
Which Sulfacetamide supplement interactions are the most serious?
None of the Sulfacetamide supplement interactions on file are currently rated major. The most significant are the 19 moderate-rated ones — combinations that may need monitoring, a dose adjustment, or separated timing. Still worth a quick look through the ranked list for anything you take daily. Jump to the ranked list.
Can I take vitamins or supplements while on Sulfacetamide?
That depends entirely on which supplement. The honest answer for Sulfacetamide is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like AK-Sulf have the same supplement interactions as Sulfacetamide?
Yes — AK-Sulf all contain Sulfacetamide, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Sulfacetamide and my other medications?
This page covers Sulfacetamide against supplements and herbal ingredients. Checking Sulfacetamide against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Sulfacetamide Ophthalmic drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.