Medication interaction hub

What Supplements Interact with Acepromazine?

Acepromazine brand name: Atravet. Every interaction below applies to the brands too.

158 Interactions 11 Major 118 Moderate 29 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Acepromazine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Acepromazine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Alcohol tops my concerns with acepromazine, a phenothiazine tranquilizer. Beer and wine both carry major ratings backed by human data, because they deepen its sedation and can add other side effects. That is the dominant pattern here: 78 of the 158 flagged ingredients, kava among them, are sedating in their own right, and layering them onto a drug built to quiet the nervous system can go further than intended. With 11 entries rated major, I would treat this list as a genuine safety check, not background reading.

Beyond sedation, about 30 ingredients add anticholinergic effects such as dry mouth, blurred vision, and confusion, and another 20 can make skin burn faster in the sun, a sensitivity acepromazine already carries as a phenothiazine. Activated charcoal is different; it can block absorption of oral doses, so space the two well apart. Most of the remaining entries are moderate, with 29 rated minor, and they largely repeat these same themes.

— , Clinical Pharmacist · July 18, 2026

Major 11 Moderate 118 Minor 29 No known interaction 1,294

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Acepromazine: Top Interactions at a Glance

The Acepromazine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 158 interacting ingredients — plus 1,294 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Acepromazine Combinations Today

The Acepromazine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Toothed Clubmoss + Acepromazinei

In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.

Read the full interaction Moderate Likelihood Possible Black Currant + Acepromazinei

Theoretically, black currant seed oil might increase the risk of seizure in patients receiving phenothiazines.

Read the full interaction Moderate Likelihood Possible Phosphatidylserine + Acepromazinei

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Read the full interaction Minor Likelihood Possible Coffee + Acepromazinei

Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Read the full interaction Minor Likelihood Possible Caffeine + Acepromazinei

Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Read the full interaction Moderate Likelihood Possible Ashwagandha + Acepromazinei

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.

Read the full interaction
The complete list

Every Supplement Checked Against Acepromazine

All 1,452 ingredients in our database, ranked by severity — 158 with a Acepromazine interaction on file and 1,294 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Acepromazine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Toothed Clubmoss with Acepromazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopol...

Full Toothed Clubmoss + Acepromazine answer

Can you take Black Currant with Acepromazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black currant seed oil might increase the risk of seizure in patients receiving phenothiazines.

Full Black Currant + Acepromazine answer

Can you take Phosphatidylserine with Acepromazine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Full Phosphatidylserine + Acepromazine answer

Can you take Coffee with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Coffee + Acepromazine answer

Can you take Caffeine with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Caffeine + Acepromazine answer

Can you take Cocoa with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Cocoa + Acepromazine answer

Can you take Cola Nut with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of the caffeine in cola nut.

Full Cola Nut + Acepromazine answer

Can you take Green Coffee with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Green Coffee + Acepromazine answer

Can you take Green Tea with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Green Tea + Acepromazine answer

Can you take Guarana with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Guarana + Acepromazine answer

Can you take Ilex Guayusa with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Ilex Guayusa + Acepromazine answer

Can you take Karaya Gum with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption o...

Full Karaya Gum + Acepromazine answer

Can you take Marshmallow with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.

Full Marshmallow + Acepromazine answer

Can you take Oolong Tea with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine in oolong tea.

Full Oolong Tea + Acepromazine answer

Can you take Pu-erh Tea with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.

Full Pu-erh Tea + Acepromazine answer

Can you take Rhodiola with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.

Full Rhodiola + Acepromazine answer

Can you take Xanthan Gum with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.

Full Xanthan Gum + Acepromazine answer

Can you take Baikal Skullcap with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative propert...

Full Baikal Skullcap + Acepromazine answer

Can you take Calabar Bean with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking calabar bean might reduce the effects of anticholinergic drugs.

Full Calabar Bean + Acepromazine answer

Can you take Calendula with Acepromazine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.

Full Calendula + Acepromazine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Acepromazine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Acepromazine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Acepromazine sits in 6 interaction categories. Open any one to see what the group means:

Cns Depressants 78 ingredients

Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.

78 of the supplement ingredients on this page reach Acepromazine through this category.

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Acepromazine through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Acepromazine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Acepromazine through this category.

Phenothiazines 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Acepromazine through this category.

Antipsychotic Drugs 8 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

8 of the supplement ingredients on this page reach Acepromazine through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Acepromazine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Acepromazine.

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Pharmacist Counseling Corner

Acepromazine & Supplements: Common Questions

What supplements interact with Acepromazine?
In our interaction database, 158 supplement and herbal ingredients have an interaction with Acepromazine on file — 11 rated major, 118 moderate, and 29 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Beer, Wine, 1,4-butanediol.
Which Acepromazine supplement interactions are the most serious?
The 11 major-rated combinations — led by Beer, Wine, 1,4-butanediol, Activated Charcoal and Gamma-hydroxybutyrate (ghb) — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Acepromazine?
That depends entirely on which supplement. The honest answer for Acepromazine is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Atravet have the same supplement interactions as Acepromazine?
Yes — Atravet all contain Acepromazine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Acepromazine and my other medications?
This page covers Acepromazine against supplements and herbal ingredients. Checking Acepromazine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.