Drug & supplement interaction

Hypnotherapy + Duloxetine

Duloxetine brand names: Cymbalta, Drizalma Sprinkle, Irenka.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Hypnotherapy and Duloxetine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Hypnotherapy and Duloxetine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Duloxetine and Hypnotherapy in our sources. This does not guarantee that the combination is completely free of risk — research on Hypnotherapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Hypnotherapy at all — not against Duloxetine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Hypnotherapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Hypnotherapy safety at a glance

Hypnotherapy overall Generally safe Generally safe when guided by a trained, licensed practitioner.
Pregnancy Possibly Safe When hypnotherapy is used appropriately. Use of self-hypnosis during labor following teaching sessions during pregnancy has not been shown to affect birthweight... Read the full pregnancy detail
Breastfeeding Generally safe No physical product is ingested, so it poses little direct risk while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Duloxetine and Hypnotherapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Hypnotherapy and Duloxetine May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so having Hypnotherapy while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Drowsiness / Anxiety or restlessness / Trouble sleeping / Dizziness / Headache Additional detail

    Hypnotherapy

    “Anxiety, dizziness, drowsiness, headaches, insomnia, and nervousness have been reported in clinical research.”

    Hypnotherapy · Natural Medicines adverse-effect record, reported in anxiety.

    1 source cited
    1. 106960. Lam TH, Chung KF, Lee CT, Yeung WF, Yu BY. Hypnotherapy for insomnia: A randomized controlled trial comparing generic and disease-specific suggestions. Complement Ther Med. 2018;41:231-239. PubMed

    Duloxetine

    Listed in the ADVERSE REACTIONS section of the FDA label for Duloxetine. Read the label on DailyMed ›

  • Nausea Additional detail

    Hypnotherapy

    “Nausea has been reported in clinical research.”

    Hypnotherapy · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 106960. Lam TH, Chung KF, Lee CT, Yeung WF, Yu BY. Hypnotherapy for insomnia: A randomized controlled trial comparing generic and disease-specific suggestions. Complement Ther Med. 2018;41:231-239. PubMed

    Duloxetine

    Listed in the ADVERSE REACTIONS section of the FDA label for Duloxetine. Read the label on DailyMed ›

Effects for Duloxetine come from the ADVERSE REACTIONS section of its FDA label; effects for Hypnotherapy come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Hypnotherapy in Pregnancy & Breastfeeding

Pregnancy Possibly Safe

When hypnotherapy is used appropriately. Use of self-hypnosis during labor following teaching sessions during pregnancy has not been shown to affect birthweight, well-being of the newborn, admission or re-admission for neonatal care, maternal stay in the hospital, readmission to hospital, lactation establishment, or ability to care for the infant. However, the use of hypnotherapy should not delay the time to diagnosis or treatment with more proven therapies.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Hypnotherapy or Duloxetine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Hypnotherapy or Duloxetine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Duloxetine

This page covers Hypnotherapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Duloxetine page lists 132 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Lithium (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 107 moderate · 20 minor.

Open the Duloxetine interaction page

How much people look this up

Where Hypnotherapy and Duloxetine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Hypnotherapy
Steady interest

#897 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Duloxetine
Top 5%

#47 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hypnotherapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Hypnotherapy and Duloxetine records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Hypnotherapy

What is Hypnotherapy?

  • Irritable bowel syndrome (IBS)
  • Anxiety and stress
  • Pain management
  • Smoking cessation
  • Sleep problems
  • Habit and weight management

Hypnotherapy is a mind-body technique where a trained therapist guides you into a focused, relaxed state to help you change thoughts, feelings, or behaviors. It is not a supplement or herb, and when done by a qualified professional it is generally considered safe. Evidence is strongest for conditions like irritable bowel syndrome and certain types of pain, but results vary from person to person.

Not applicable (mind-body therapy) · Sessions with a trained therapist, self-hypnosis, audio recordings, guided apps

An interaction check asks whether these two react with each other — it does not ask whether Hypnotherapy is a good idea for someone in your situation. Here is what our Hypnotherapy record says about it on its own.

Hypnotherapy: dosing

There is no standard "dose" for hypnotherapy because it is a therapy, not a substance. Treatment is usually given as a series of sessions with a trained therapist, and the number of sessions varies based on your goals and the condition being treated.Many programs involve several weekly sessions, and you may also practice self-hypnosis or use guided recordings between visits. Follow the plan recommended by your qualified provider.

From our Hypnotherapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Hypnotherapy monograph & all interactions
Medication

About Duloxetine

What Is Duloxetine Used For?

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Duloxetine delayed-release capsules treat major depressive disorder (MDD) and generalized anxiety disorder (GAD) in adults. They also manage diabetic peripheral neuropathic pain (nerve pain from diabetes), fibromyalgia, and chronic musculoskeletal pain (such as chronic low back pain and pain from osteoarthritis) in adults.

GAD is also approved in pediatric patients 7 years and older for Cymbalta, Drizalma Sprinkle, and certain duloxetine delayed-release capsule products. Fibromyalgia is approved in patients 13 years and older for Cymbalta and some duloxetine delayed-release capsule products. Age-specific approvals vary by product — follow your prescriber's guidance on which product is right for your age group.

See full Duloxetine drug information
Keep checking

Other Drugs & Hypnotherapy

Browse every other medication we’ve checked against Hypnotherapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Hypnotherapy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Hypnotherapy list.

See the full Hypnotherapy interactions page
See every supplement checked against Duloxetine, ranked by severity
Evidence & sources

Hypnotherapy References

The 3 references that drive our Hypnotherapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Werner A, Uldbjerg N, Zachariae R, Nohr EA. Effect of self-hypnosis on duration of labor and maternal and neonatal outcomes: a randomized controlled trial. Acta Obstet Gynecol Scand. 2013;92(7):816-23. PubMed
  2. Madden K, Middleton P, Cyna AM, Matthewson M, Jones L. Hypnosis for pain management during labour and childbirth. Cochrane Database Syst Rev. 2016;2016(5):CD009356. PubMed
  3. Lam TH, Chung KF, Lee CT, Yeung WF, Yu BY. Hypnotherapy for insomnia: A randomized controlled trial comparing generic and disease-specific suggestions. Complement Ther Med. 2018;41:231-239. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Hypnotherapy While Taking Duloxetine: Common Questions

Is it safe to have Hypnotherapy while taking Duloxetine?
We do not list a known interaction between Hypnotherapy and Duloxetine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Hypnotherapy and Duloxetine have any of the same side effects?
Yes — our sources link each of them separately to 6 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Duloxetine interact with any supplements?
Yes. Duloxetine has documented interactions with 132 supplements in our database — Hypnotherapy is not one of them. The Duloxetine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Hypnotherapy monograph Uses, safety profile, and every drug interaction in one place Duloxetine drug information The full plain-English guide to this medication Duloxetine supplement interactions Every supplement checked against Duloxetine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Duloxetine and Hypnotherapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.