Idebenone + Avibactam Sodium, Ceftazidime
Avibactam Sodium, Ceftazidime brand name: Avycaz.
We found no known interaction between Idebenone and Avibactam Sodium, Ceftazidime in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Idebenone and Avibactam Sodium, Ceftazidime
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Avibactam Sodium, Ceftazidime and Idebenone in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Idebenone at all — not against Avibactam Sodium, Ceftazidime, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Idebenone safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Avibactam Sodium, Ceftazidime
This page covers Idebenone only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Avibactam Sodium, Ceftazidime page lists 37 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: African Wild Potato (moderate), Bacillus Coagulans (moderate), Bacillus Subtilis (moderate), Banderol (moderate) and Bifidobacterium Animalis Subsp. Lactis (moderate).
By severity: 36 moderate · 1 minor.
From our pharmacist’s overview on the Avibactam Sodium, Ceftazidime page
“Avycaz, the combination of ceftazidime and avibactam, is an intravenous antibiotic for serious infections, and its supplement list is calmer than that setting might suggest. None of the 37 ingredients on file carries a major rating; 36 are moderate and one is minor.”
Reviewed by 2 · Jul 18, 2026
Taking Idebenone as Part of a Dietary Supplement Product? Check It for Interactions
We hold 17 real supplement products containing Idebenone, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Idebenone. Even though Idebenone itself has no known interaction with Avibactam Sodium, Ceftazidime, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Idebenone and Avibactam Sodium, Ceftazidime Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#635 of 1,452 supplements looked up here in the last 7 days
#1,405 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Idebenone reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Idebenone and Avibactam Sodium, Ceftazidime records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Idebenone
What is Idebenone?
- Antioxidant support
- Brain and memory health
- Mitochondrial disorders
- Anti-aging skin care
- General energy support
Idebenone is a synthetic, lab-made antioxidant related to coenzyme Q10. It has been studied mostly as a prescription drug for certain rare mitochondrial and neurological conditions, and is also used in some skin-care products, but evidence for over-the-counter supplement use is limited. Talk with your pharmacist or doctor before using it.
Synthetic compound (a lab-made analog of coenzyme Q10) · Capsules, tablets, topical creams and serums
An interaction check asks whether these two react with each other — it does not ask whether Idebenone is a good idea for someone in your situation. Here is what our Idebenone record says about it on its own.
Idebenone: dosing
There is no standard supplement dose of idebenone that experts agree on. Doses used in medical studies for specific diseases were set by researchers and differ from what is found in over-the-counter products.If you choose to use an idebenone supplement, follow the directions on the product label and do not exceed the recommended amount.
From our Idebenone monograph — the full record covers uses, side effects and every documented interaction.
About Ceftazidime and Avibactam Injection
What Is Ceftazidime and Avibactam Injection Used For?
Brand name: Avycaz
Avycaz (ceftazidime and avibactam) is used to treat three types of serious bacterial infections in adults and children at least 31 weeks gestational age: complicated intra-abdominal infections (cIAI), complicated urinary tract infections (cUTI) including pyelonephritis (a kidney infection), and hospital-acquired bacterial pneumonia or ventilator-associated bacterial pneumonia (HABP/VABP). All three of these infections must be caused by specific susceptible gram-negative bacteria for Avycaz to be effective.
When treating complicated intra-abdominal infections, Avycaz must be used together with metronidazole, another antibiotic. Avycaz is only meant for infections proven or strongly suspected to be caused by bacteria that it can actually fight — using it otherwise can lead to antibiotic resistance.
Other Drugs & Idebenone
Browse every other medication we’ve checked against Idebenone — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Idebenone against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Losartan Potassium ›
- Aspirin ›
- Abemaciclib ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Idebenone list.
Idebenone References
The 25 references that drive our Idebenone monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Mariotti C, Solari A, Torta D, et al. Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial. Neurology 2003;60:1676-9. PubMed
- Filla A, Moss AJ. Idebenone for treatment of Friedreich's ataxia? Neurology 2003;60:1569-70. PubMed
- Hausse AO, Aggoun Y, Bonnet D, et al. Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia. Heart 2002;87:346-9. PubMed
- Schols L, Vorgerd M, Schillings M, et al. Idebenone in patients with Friedreich ataxia. Neurosci Lett 2001;306:169-72. PubMed
- Lerman-Sagie T, Rustin P, Lev D, et al. Dramatic improvement in mitochondrial cardiomyopathy following treatment with idebenone. J Inherit Metab Dis 2001;24:28-34. PubMed
- Rustin P, von Kleist-Retzow JC, Chantrel-Groussard K, et al. Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study. Lancet 1999;354:477-9. PubMed
- Weyer G, Babej-Dolle RM, Hadler D, et al. A controlled study of 2 doses of idebenone in the treatment of Alzheimer's disease. Neuropsychobiology 1997;36:73-82. . PubMed
- Ikejiri Y, Mori E, Ishii K, et al. Idebenone improves cerebral mitochondrial oxidative metabolism in a patient with MELAS. Neurology 1996;47:583-5. PubMed
- Pisano P, Durand A, Autret E, et al. Plasma concentrations and pharmacokinetics of idebenone and its metabolites following single and repeated doses in young patients with mitochondrial encephalomyopathy. Eur J Clin Pharmacol 1996;51:167-9. PubMed
- Ihara Y, Namba R, Kuroda S, et al. Mitochondrial encephalomyopathy (MELAS): pathological study and successful therapy with coenzyme Q10 and idebenone. J Neurol Sci 1989;90:263-71. PubMed
- Gutzmann H, Hadler D. Sustained efficacy and safety of idebenone in the treatment of Alzheimer's disease: update on a 2-year double-blind multicentre study. J Neural Transm 1998;54:301-10. PubMed
- Di Prospero NA, Sumner CJ, Penzak SR, et al. Safety, tolerability, and pharmacokinetics of high-dose idebenone in patients with Friedreich ataxia. Arch Neurol 2007;64:803-8. PubMed
- Buyse GM, Voit T, Schara U, DELOS Study Group. Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial. Lancet. 2015;385(9979) PubMed
- Corben LA, Lynch D, Pandolfo M, Schulz JB, Delatycki MB; Clinical Management Guidelines Writing Group. Consensus clinical management guidelines for Friedreich ataxia. Orphanet J Rare Dis. 2014;9:184. DOI
- Di Prospero NA, Baker A, Jeffries N, Fischbeck KH. Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial. Lancet Neurol. 2007;6(10):878-86. PubMed
- Lagedrost SJ, Sutton MS, Cohen MS, et al. Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month phase III study (IONIA). Am Heart J. 2011;161(3):639-645.e1. PubMed
- Lynch DR, Perlman SL, Meier T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-7. PubMed
- Mc Aleer MA, Collins P. Allergic contact dermatitis to hydroxydecyl ubiquinone (idebenone) following application of anti-ageing cosmetic cream. Contact Dermatitis. 2008;59(3):178-9. PubMed
- McDaniel DH, Neudecker BA, DiNardo JC, Lewis JA 2nd, Maibach HI. Clinical efficacy assessment in photodamaged skin of 0.5% and 1.0% idebenone. J Cosmet Dermatol. 2005;4(3):167-73. PubMed
- Meier T, Perlman SL, Rummey C, Coppard NJ, Lynch DR. Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study. J Neurol. 2012;25 PubMed
- Pineda M, Arpa J, Montero R, et al. Idebenone treatment in paediatric and adult patients with Friedreich ataxia: long-term follow-up. Eur J Paediatr Neurol. 2008;12(6):470-5. PubMed
- Catarino CB, von Livonius B, Priglinger C, et al. Real-world clinical experience with idebenone in the treatment of leber hereditary optic neuropathy. J Neuroophthalmol. 2020 Dec;40(4):558-565.
- Kosa P, Wu T, Phillips J, et al. Idebenone does not inhibit disability progression in primary progressive MS. Mult Scler Relat Disord. 2020 Oct;45:102434. PubMed
- Zhao X, Zhang Y, Lu L, Yang H. Therapeutic effects of idebenone on leber hereditary optic neuropathy. Curr Eye Res. 2020 Oct;45(10):1315-1323. PubMed
- Yuan LL, Chen TY, Huang ZQ. Effects of paroxetine hydrochloride combined with idebenone on inflammatory factors and antioxidant molecules in treatment of depression after ischemic stroke. Pak J Med Sci 2023;39(1):17-22. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Avibactam Sodium, Ceftazidime Is Linked to Lower Levels of 7 Nutrients
Natural Medicines records Avibactam Sodium, Ceftazidime as a medicine that can lower these. This is not an interaction with Idebenone — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Avibactam Sodium, Ceftazidime nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Idebenone and Avibactam Sodium, Ceftazidime Together: Common Questions
Is it safe to take Idebenone with Avibactam Sodium, Ceftazidime?
Do Idebenone and Avibactam Sodium, Ceftazidime have any of the same side effects?
Does Avibactam Sodium, Ceftazidime interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.